麻豆传媒

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Findings from the first international randomized controlled trial to compare patient outcomes following treatment with large-bore mechanical thrombectomy (LBMT) versus catheter-directed thrombolysis (CDT) for intermediate-risk pulmonary embolism (PE) found that LBMT is superior with respect to the hierarchically-tested aggregated outcome of all-cause mortality, intracranial hemorrhage, major bleeding, clinical deterioration and/or escalation to bailout therapy, and postprocedural ICU admission and length of stay. Findings were reported today at TCT 2024, the annual scientific symposium of the Cardiovascular Research Foundation (CRF). TCT is the world鈥檚 premier educational meeting specializing in interventional cardiovascular medicine. Results were also published simultaneously in Circulation.

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A new analysis led by researchers at Washington University School of Medicine in St. Louis has revealed detailed 3D maps of the internal structures of multiple tumor types. These cancer atlases reveal how different tumor cells 鈥� and the cells of a tumor鈥檚 surrounding environment 鈥� are organized, in 3D, and how that organization changes when a tumor spreads to other organs. The detailed findings offer scientists valuable blueprints of tumors that could lead to new approaches to therapy and spark a new era in the field of cancer biology, according to the researchers.

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Mount Sinai study shows how the heart and brain interact to influence sleep patterns and help with recovery

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Complex images in a social media post tend to capture greater user attention, leading to increased engagement with social media posts, according to new research from聽Vamsi Kanuri, the Viola D. Hank Associate Professor of Marketing at the University of Notre Dame鈥檚 Mendoza College of Business.

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The largest trial to examine the impact of colchicine in acute myocardial infarction (MI) found that both acute and long-term colchicine use did not reduce cardiovascular death, myocardial infarction, stroke, or ischemia-driven revascularization.

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Dr. Sedrak, who directs the Cancer and Aging Program at the UCLA Health Jonsson Comprehensive Cancer Center(Link opens in new window), discusses what inspired his work, the challenges cancer survivors face as they age, and the exciting advancements in cancer and aging research that could reshape patient care in the years to come.

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Results from the large-scale randomized ECLIPSE trial found that a lesion preparation strategy of routine orbital atherectomy had similar outcomes compared with conventional balloon angioplasty prior to implantation of a drug-eluting stent (DES) in severely calcified coronary arteries.

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New research led by Cedars-Sinai investigators has reversed liver fibrosis, a gradual buildup of scar tissue in the liver, in laboratory mice. Their achievement marks a crucial step toward potentially creating new treatments for patients with this condition, which can lead to life-threatening diseases including cirrhosis, liver failure and liver cancer.

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Retrofitting a portion of the US shipping fleet from internal combustion engines to battery-electric systems could significantly reduce greenhouse gas emissions and be largely cost effective by 2035, according to a new study from Berkeley Lab researchers.

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A new, large study led by American Cancer Society (ACS) researchers found that lack of health insurance coverage accounts for a significant proportion of racial and ethnic disparities in advanced-stage diagnosis of multiple cancers.

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Researchers at the Icahn School of Medicine at Mount Sinai have discovered a way that ovarian cancer tumors manipulate their environment to resist immunotherapy and identified a drug target that could overcome that resistance. The study, published in the October 30 online issue of Cell used a cutting-edge spatial genomics technology and preclinical animal models, with tumor specimens from ovarian cancer patients further validating the findings. They found that ovarian cancer cells produce a molecule called Interleukin-4 (IL-4), which is typically associated with asthma and the skin condition eczema, also known as atopic dermatitis. The study went on to find that the cancer cells used IL-4 to create a protective environment that kept away killer immune cells, making the tumors resistant to immunotherapy. A drug, dupilumab, which blocks IL-4鈥檚 activity, has been approved by the Food and Drug Administration (FDA) and is already used to treat asthma and eczema. This new study suggests dupi

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A new initiative by the American Academy of Dermatology aims to shed light on an often misunderstood and debilitating condition, hidradenitis suppurativa (HS). HS is a chronic progressive condition that can cause painful and boil-like bumps, particularly in a patient鈥檚 armpits, thighs, and groin.

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Most small kidney stones can pass on their own. However, kidney stones that are too large to pass on their own or cause bleeding, kidney damage or ongoing urinary tract infections may require surgical treatment. Dr. Aaron Potretzke, a Mayo Clinic urologist in Rochester, Minnesota, explains some of the different surgical options for removing kidney stones.

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A maioria dos c谩lculos renais podem ser expelidos por conta pr贸pria. "No entanto, os c谩lculos renais que s茫o grandes demais para serem expelidos sozinhos ou que causam sangramento, danos nos rins ou infec莽玫es urin谩rias recorrentes podem exigir tratamento cir煤rgico." O Dr. Aaron Potretzke, urologista da Mayo Clinic em Rochester, Minnesota, explica algumas das op莽玫es cir煤rgicas para remover os c谩lculos renais.

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Alternating between sitting and standing at work decreases sedentary behavior, but it has no effect on lowering blood pressure, according to a study led by a West Virginia University epidemiologist. Researchers also found that too much standing during work may have negative effects on cardiovascular health.

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La mayor铆a de los c谩lculos renales pueden ser expulsados por su cuenta. "Sin embargo, los c谩lculos renales que son demasiado grandes para ser expulsados por s铆 solos o que causan sangrado, da帽o renal o infecciones urinarias recurrentes pueden requerir tratamiento quir煤rgico." El Dr. Aaron Potretzke, ur贸logo en Mayo Clinic en Rochester, Minnesota, explica algunas de las opciones quir煤rgicas para extirpar los c谩lculos renales.

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A research team has established a Virus-Induced Gene Silencing (VIGS) system in taro, enabling researchers to rapidly verify gene functions in this underutilized crop.