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Anyone watching Kelly Rowe set records as a sprinter at Mansfield Lake Ridge High School and then compete on a track scholarship at the University of Mississippi, would assume she was in peak health. They鈥檇 have no reason to suspect she had been on a battery of medications and gone to countless doctor appointments ever since she was 8. That鈥檚 when she was diagnosed with autoimmune hepatitis, a condition that attacks the liver and leads to long-term damage.

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Scientists have long been trying to tease apart hepatitis A virus, to understand its inner workings and how it functions in the human body. Infectious disease researchers at the UNC School of Medicine have discovered that a little-known protein, PDGFA-associated protein 1 (PDAP1), is used as a pawn by hepatitis A virus to replicate and infect cells in the liver.

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UChicago Medicine's current clinic on Salt Creek Lane in Hinsdale will close Nov. 21, and open across the street in a new, larger facility Dec. 2.

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People with chronic liver disease can be categorized into four distinct risk groups based on the different barriers they face in obtaining outpatient care, barriers that increase their odds of requiring hospitalization.

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Alcohol-related deaths in the U.S. nearly doubled from 1999 to 2020. The sharpest spike occurred among 25鈥�34-year-olds (nearly fourfold), while individuals aged 55鈥�64 had the highest rates. Men consistently had higher rates but women saw the largest proportional rise, with deaths increasing 2.5 times. Asian and Pacific Islander communities experienced the steepest ethnic increase, while the Midwest saw the greatest regional rise (2.5 times), followed by the Northeast, West, and South.

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Fecal Microbiota Transplantation for Childhood Constipation and More in the November Issue of AJG

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The article, Safety of Kidney Transplantation from Donors with HIV, details findings supporting HIV-to-HIV kidney transplants as safe and just as effective as those using organs from donors without HIV.

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Stents to treat various blockages in the human body can themselves become blocked, but a new sensor developed at the University of Michigan for stents that are used in the bile duct may one day help doctors detect and treat stent blockages early, helping keep patients healthier.

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New research led by Cedars-Sinai investigators has reversed liver fibrosis, a gradual buildup of scar tissue in the liver, in laboratory mice. Their achievement marks a crucial step toward potentially creating new treatments for patients with this condition, which can lead to life-threatening diseases including cirrhosis, liver failure and liver cancer.

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Latest research in the FASEB Journal reveals an antibody called bFKB1 improves liver disease and atherosclerosis in a mouse model of metabolic dysfunction-associated steatohepatitis (MASH), which is associated with obesity.

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Surgeons recently performed Mayo Clinic's first paired living liver donation, a significant first step in helping more people with liver failure get a lifesaving transplant.

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An 鈥渙ut-of-this-world鈥� project has the potential to transform the future of tissue engineering and liver transplantation through innovative research conducted aboard the International Space Station (ISS).

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NIBIB-funded researchers are working to bring in vivo gene editing to the fore. Through rational engineering of lipid nanoparticles, this collaborative team developed a way to effectively target specific organs in the body to precisely deliver therapeutic cargo, including gene-editing molecules.

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The liver transplant program at Corewell Health in Southeast Michigan consistently ranks among the highest quality liver transplant programs in Michigan and the nation, according to federal quality data.

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The Organ Procurement and Transplantation Network (OPTN) has periodically revamped its organ allocation policies over the years to prioritize sicker children over adults and expand the geographic area of donors. A recent study led by Children鈥檚 Hospital Los Angeles showed that this has helped improve the odds for children with PALF.