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Synchronisation between the central circadian clock and the circadian clocks of tissues preserves their functioning and prevents ageing

鈥� Two complementary research articles, published simultaneously in the journals Science and Cell Stem Cell by a team of scientists from the UPF and IRB Barcelona, reveal that central and peripheral circadian clocks coordinate to regulate the daily...
1-May-2024 3:05 PM EDT Add to Favorites

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Researchers observe at the atomic level the neuronal 'gate' for essential molecules in learning and memory

The protein Asc-1 serves as the gateway (either for entry or exit) for fundamental amino acids involved in cognitive processes. A new study now unveils its structure and mechanism of action.
17-Apr-2024 4:05 AM EDT Add to Favorites

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Characterization of mutational 鈥渃oldspots鈥� in the cancer genome

Researchers at IRB Barcelona report mutation rate variation across the human genome. Regions with low mutation rates correlate with hypomethylation (low methylation levels), a way cells control which genes are turned on or off.
10-Apr-2024 9:05 AM EDT Add to Favorites

Researchers from IRB Barcelona and Sant Joan de D茅u unveil the origin of second pediatric cancers and chemotherapy-induced mutations in healthy tissues

A team from IRB Barcelona and Sant Joan de D茅u Hospital 路 IRSJD has studied the cases of four children who have experienced two cancers during childhood and has addressed the origin of the second tumour.
18-Mar-2024 7:05 PM EDT Add to Favorites

Launch of a pioneering translational research programme in Europe

- The TRIP initiative establishes three new joint laboratories that bring together fundamental biomedical research and clinical research with the aim of accelerating the delivery of results to patients. - TRIP will focus on emerging fields such as...
6-Mar-2024 8:05 AM EST Add to Favorites

New drug reveals a key mechanism to overcome resistance to protein degraders

Protein degraders offer a novel approach to targeting undruggable diseases by hijacking the cell's degradation machinery.
30-Jan-2024 6:05 AM EST Add to Favorites

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Chemotherapy becomes more efficient when senescent cells are eliminated by immunotherapy

Researchers from IRB Barcelona describe a mechanism by which senescent cells generated by chemotherapy survive inside tumours.
23-Jan-2024 9:30 AM EST Add to Favorites

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Bladder tumours reduced by 90% using nanorobots

The research, which was conducted on mice, demonstrates how these tiny nanomachines are propelled by urea present in urine and precisely target the tumour, attacking it with a radioisotope carried on their surface.
15-Jan-2024 7:05 AM EST Add to Favorites


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About

We are a biomedical research center that works to achieve a society free of diseases. Our mission is to carry out research of excellence to cure cancer and other diseases linked to ageing.

Our research results reach patients through technology transfer, which is accomplished by establishing collaborations with the pharmaceutical industry and the main hospitals.
We are also committed to knowledge. To this end, we offer the best training in biomedical sciences to young researchers, students and visitors, and maintain an open dialogue with citizens through a range of scientific communication and outreach activities.
IRB Barcelona was founded in 2005 by the 鈥淕eneralitat de Catalunya鈥� and the University of Barcelona (UB) and is located in the Barcelona Science Park (PCB). We are a CERCA centre that forms part of the Barcelona Institute of Science and Technology (BIST). The State Research Agency has awarded IRB Barcelona four consecutive Severo Ochoa" Centre of Excellence Accreditations (2011, 2015, 2019 and 2023).

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