News Feature Channel: Alzheimer's and Dementia

Researchers Create 'Mini Brains' to Model Lewy Body Dementia and Pinpoint Treatments

Mayo Clinic — Tue, 15 Oct 2024 11:25:30 EST

Lewy body dementia (LBD) is a progressive neurodegenerative disease that shares traits with both Parkinson's disease and Alzheimer's disease but can be more difficult to diagnose. Symptoms can include hallucinations, movement disorders, cognitive issues, sleep problems and depression.

الباحثون يبتكرون "أدمغة مصغرة" لنمذجة خرف أجسام ليوي وتحديد العلاجات المناسبة

Mayo Clinic — Mon, 14 Oct 2024 14:15:13 EST

خرف أجسام ليوي هو مرض تنكسي عصبي متفاقم يشترك في بعض سماته مع داء باركينسون و داء الزهايمر، ولكنه قد يكون أكثر صعوبة في التشخيص. يمكن أن تشمل الأعراض الهلوسات واضطرابات الحركة ومشاكل في الإدراك واضطرابات النوم والاكتئاب.

Pesquisadores criam "minicerebros" para modelar a demencia por corpos de Lewy e identificar tratamentos

Mayo Clinic — Mon, 14 Oct 2024 13:55:00 EST

A demencia por corpos de Lewy (DCL) e uma doenca neurodegenerativa progressiva que compartilha caracteristicas tanto da doenca de Parkinson quanto da doenca de Alzheimer, mas que pode ser mais dificil de ser diagnosticada. Os sintomas podem incluir alucinacoes, disturbios do movimento, problemas cognitivos, problemas de sono e depressao.

Investigadores Crean "Minicerebros" Para Modelar La Demencia Con Cuerpos De Lewy E Identificar Tratamientos

Mayo Clinic — Mon, 14 Oct 2024 13:50:00 EST

La demencia con cuerpos de Lewy (DCL) es una enfermedad neurodegenerativa progresiva que comparte caracteristicas tanto de la enfermedad de Parkinson cuanto de la enfermedad de Alzheimer, pero que puede ser mas dificil de diagnosticar. Los sintomas pueden incluir alucinaciones, trastornos del movimiento, problemas cognitivos, problemas para dormir y depresion.

Smaller Vial Size for Alzheimer's Drug Could Save Medicare Hundreds of Millions Per Year

University of California, Los Angeles (UCLA), Health Sciences — Mon, 14 Oct 2024 11:00:00 EST

Medicare could save up to 74% of the money lost from discarded Alzheimer's drug lecanemab by the simple introduction of a new vial size that would reduce the amount of unused medication that is thrown away.

Non-Invasive Eye Test for Multiple Diseases to Advance Under $4.8m NIH Award

Indiana University — Fri, 11 Oct 2024 15:05:19 EST

Researchers at the IU School of Optometry and IU Luddy School of Informatics, Computing and Engineering will advance next-generation technology that uses a simple eye scan to assist in the early detection of conditions such as Alzheimer's disease, diabetes and heart disease.

Newly Discovered Genetic Marker Could Pave the Way for Future Alzheimer's Disease Therapeutics

Indiana University — Tue, 08 Oct 2024 16:05:43 EST

Researchers have identified a new genetic marker that could play a role in the development of Alzheimer's disease and lead to novel therapeutic targets and diagnostic tools for the disease.

Extra Virgin Olive Oil May Preserve Cognitive Function in Down Syndrome

Alzheimer's Center at Temple University Lewis Katz School of Medicine — Mon, 07 Oct 2024 17:05:34 EST

Researchers working with the Alzheimer's Center at Temple (ACT) recently investigated the effect of extra virgin olive oil (EVOO) on brain health and memory to determine if consumption of extra virgin olive oil, the main component of the Mediterranean diet, can delay cognitive decline in people with Down Syndrome (DS).

First Infusion in Houston for New Alzheimer's Drug Administered at UTHealth Houston

University of Texas Health Science Center at Houston — Mon, 07 Oct 2024 10:05:36 EST

UTHealth Houston is the first institution in Houston to administer an FDA-approved drug, Kisunla (donanemab-azbt), for the treatment of early symptomatic Alzheimer's disease.

Brain Network Study Reveals Clues About Dementia's Behavior Changes

Michigan Medicine - University of Michigan — Mon, 07 Oct 2024 10:05:15 EST

Dementia doesn't just erode memory - it also changes behavior and mental health. A new study shows the brain's salience network and tau protein may be involved.

Key Mechanisms in Asymptomatic Alzheimer's Disease Brains May Protect Against Cognitive Decline

Indiana University — Wed, 02 Oct 2024 13:05:22 EST

Researchers are studying the brains of a subset of people with asymptomatic Alzheimer's disease who, despite having amyloid plaque and tau buildup postmortem, experienced no diagnosable dementia symptoms while they were living.

Community-Based Programs in Senior Centers May Lower Health Care Use and Costs for People with Dementia

Rutgers University-New Brunswick — Wed, 02 Oct 2024 12:05:07 EST

Living with dementia in communities with senior centers providing access to adult day health and social services was associated with fewer hospitalizations and lower health care use and Medicare costs, according to researchers from Rutgers University-New Brunswick and the University of Massachusetts Boston.

Clinical Trial Shows Synthetic Cannabis Reduces Agitation in Alzheimer's Disease

Johns Hopkins Medicine — Wed, 02 Oct 2024 10:00:30 EST

In a study led by the Johns Hopkins University School of Medicine and Tufts University School of Medicine, researchers show that a pill form of the drug dronabinol, an FDA-approved synthetic version of marijuana's main ingredient, THC, reduces agitation in patients with Alzheimer's by an average of 30%.

New Study: Neuroscientists Spark Shelter-Seeking Response by Reactivating Memory Circuit

Johns Hopkins Medicine — Tue, 01 Oct 2024 12:05:52 EST

Using a sophisticated brain-imaging system, neuroscientists at Johns Hopkins Medicine say they have successfully reactivated a specific memory circuit in mice, causing them to seek out shelter when no shelter is actually present.

September Research Tip Sheet

Cedars-Sinai — Mon, 30 Sep 2024 12:05:13 EST

Cedars-Sinai has published a summary of key research highlights for September 2024.

Researchers Close in on Understanding Possible Cause of Alzheimer's Disease

Case Western Reserve University — Mon, 30 Sep 2024 09:00:25 EST

The National Institutes of Health (NIH) has awarded a four-year, $3.3 million grant to Case Western Reserve University researchers to investigate the potential involvement of specific brain proteins in the pathogenesis of Alzheimer's disease.

New Brain Cell Cleaner: Astrocytes Raise Possibility of Alzheimer's Disease Treatment

National Research Council of Science and Technology — Mon, 30 Sep 2024 00:00:00 EST

A research team led by Dr. Hoon Ryu from the Korea Institute of Science and Technology (KIST) has uncovered a new mechanism involving astrocytes for treating Alzheimer's disease (AD) and proposed a novel therapeutic target.

Study Finds Certain MS Therapies May Not Slow Disability Progression

American Academy of Neurology (AAN) — Wed, 25 Sep 2024 16:00:00 EST

In people with primary progressive multiple sclerosis (MS), a new study has found no difference in the amount of time before disability worsened between people taking certain medications and those not receiving treatment. The study is published in the September 25, 2024, online issue of Neurology(r), the medical journal of the American Academy of Neurology.

Are Gender and Sexual Identity Linked to Brain Health?

American Academy of Neurology (AAN) — Wed, 25 Sep 2024 16:00:00 EST

LGBTQ+ people may be more likely to have negative brain health outcomes, including a higher risk of dementia and late-life depression, than people who are cisgender and straight, according to a study published in the September 25, 2024, online issue of Neurology(r), the medical journal of the American Academy of Neurology. These results do not prove that sexual or gender diversity causes neurological diseases, they only show an association.

Grants for $3.5m From TARCC Fund New Alzheimer's Disease Research at UTHealth Houston

University of Texas Health Science Center at Houston — Thu, 19 Sep 2024 13:05:46 EST

Studies by researchers at UTHealth Houston seeking to understand the underlying pathology of Alzheimer's disease in order to discover new pathways to treatment have earned multiple awards totaling $3.5 million from the Texas Alzheimer's Research and Care Consortium (TARCC).