News Feature Channel: Kidney Disease

Denosumab Increases Risk of Emergently Treated Hypocalcemia in Advanced Chronic Kidney Disease

American College of Physicians (ACP) — Mon, 18 Nov 2024 17:00:00 EST

A target trial emulation evaluated the incidence of emergently treated hypoalcemia associated with denosumab by stage of chronic kidney disease (CKD) progression and presence of CKD-mineral and bone disorder (CKD-MBD).

Hackensack Meridian Mountainside Medical Center Nurse Wins Research Award at ACC Quality Summit

Hackensack Meridian Health (Mountainside Medical Center) — Fri, 15 Nov 2024 00:00:12 EST

Alyssa Stolarik, RN, BSN, clinical coordinator of Cardiology at Hackensack Meridian Health Mountainside Medical Center, received the Second Best Research Poster Award at the American College of Cardiology (ACC) Quality Summit held in San Antonio, Texas. Her work, titled "Improving Compliance with Post-PCI Creatinine," highlights significant advancements in the management of post-procedural care and patient outcomes. The research addresses the critical issue of acute kidney injury (AKI) post-percutaneous coronary intervention (PCI), demonstrating a marked reduction in risk-standardized AKI rates, which significantly surpasses national benchmarks.

UTSW Epidemiologist to Receive AHA Distinguished Scientist Award

UT Southwestern Medical Center — Wed, 13 Nov 2024 14:05:05 EST

Jiang He, M.D., Ph.D., Professor and Chair Designate of Epidemiology in the Peter O'Donnell Jr. School of Public Health at UT Southwestern Medical Center, is a 2024 recipient of the American Heart Association's (AHA) highest commendation, the Distinguished Scientist award. The honor recognizes Dr. He's prolific research on reducing the risks of cardiometabolic diseases, including heart disease, stroke, obesity, Type 2 diabetes, hypertension, dyslipidemia, and chronic kidney disease.

Johns Hopkins Researchers Use Electronic Diagnostic Model to Predict Acute Interstitial Nephritis (AIN) in Patients

Johns Hopkins Medicine — Tue, 12 Nov 2024 11:00:05 EST

Researchers from both Johns Hopkins Medicine and Yale University collaborated on the development and application of a diagnostic model to detect acute interstitial nephritis (AIN) in patients, which could have a lasting impact on getting patients diagnosed earlier

Ochsner Transplant Institute Among Site Collaborators in New England Journal of Medicine HIV-to-HIV Kidney Transplant Study

Ochsner Health — Mon, 11 Nov 2024 12:35:58 EST

The article, Safety of Kidney Transplantation from Donors with HIV, details findings supporting HIV-to-HIV kidney transplants as safe and just as effective as those using organs from donors without HIV.

Study: Women, Girls at Lower Risk of Acute Kidney Injury

Yale School of Medicine — Thu, 31 Oct 2024 09:45:38 EST

Fasting-Mimicking Diet Restores Kidney Function in Study

Children's Hospital Los Angeles — Wed, 30 Oct 2024 14:25:03 EST

In patients with chronic kidney disease, the loss of podocytes--part of the kidney's glomerular filtration barrier--causes irreversible disease progression. So far, physicians and researchers have found no way to effectively prevent podocyte damage, loss, and deterioration leading to end-stage kidney disease.

Advances in Minimally Invasive Kidney Stone Surgery

Mayo Clinic — Wed, 30 Oct 2024 10:50:50 EST

Most small kidney stones can pass on their own. However, kidney stones that are too large to pass on their own or cause bleeding, kidney damage or ongoing urinary tract infections may require surgical treatment. Dr. Aaron Potretzke, a Mayo Clinic urologist in Rochester, Minnesota, explains some of the different surgical options for removing kidney stones.

Avancos na cirurgia minimamente invasiva de calculo renal

Mayo Clinic — Wed, 30 Oct 2024 10:50:37 EST

A maioria dos calculos renais podem ser expelidos por conta propria. "No entanto, os calculos renais que sao grandes demais para serem expelidos sozinhos ou que causam sangramento, danos nos rins ou infeccoes urinarias recorrentes podem exigir tratamento cirurgico." O Dr. Aaron Potretzke, urologista da Mayo Clinic em Rochester, Minnesota, explica algumas das opcoes cirurgicas para remover os calculos renais.

Avances en la cirugia minimamente invasiva de calculos renales

Mayo Clinic — Wed, 30 Oct 2024 10:40:54 EST

La mayoria de los calculos renales pueden ser expulsados por su cuenta. "Sin embargo, los calculos renales que son demasiado grandes para ser expulsados por si solos o que causan sangrado, dano renal o infecciones urinarias recurrentes pueden requerir tratamiento quirurgico." El Dr. Aaron Potretzke, urologo en Mayo Clinic en Rochester, Minnesota, explica algunas de las opciones quirurgicas para extirpar los calculos renales.

التطورات في جراحة حصوات الكلى بالتدخل الجراحي المحدود

Mayo Clinic — Wed, 30 Oct 2024 10:35:10 EST

يُمكن لمعظم حصوات الكلى الصغيرة أن تمُر بشكل طبيعي. ومع ذلك، فإن حصوات الكلى الكبيرة جدًا التي لا يمكنها الخروج من تلقاء نفسها أو تسبب النزيف أو تلف الكلى أو التهابات الجهاز البولي المستمرة قد تتطلب تدخلاً جراحيًا. يشرح الدكتور آرون بوترتزكي، أخصائي المسالك البولية في مايو كلينيك بروتشستر، مينيسوتا، بعض الخيارات الجراحية لإزالة حصوات الكلى.

New Study Refines Understanding of Kidney Transplant Rejection

Rutgers University-New Brunswick — Mon, 28 Oct 2024 14:15:27 EST

Findings from Rutgers Health and other researchers may lead to more precise treatment.

Kidney Week 2024: Virtual Press Briefings

News — Mon, 28 Oct 2024 10:05:21 EST

Kidney Week 2024: Live Event

Case Western Reserve University Awarded $2.6M to Study Impact of High Blood-Pressure Medications on Chronic Kidney Disease Patients

Case Western Reserve University — Mon, 28 Oct 2024 09:00:05 EST

The National Institutes of Health awarded a four-year, $2.6 million grant to researchers at Case Western Reserve University to study how high blood-pressure drugs affect patients with chronic kidney disease (CKD).

Prabir Roy-Chaudhury, MD, PhD, FASN, to Become Next President of the American Society of Nephrology

American Society of Nephrology (ASN) — Sun, 27 Oct 2024 12:00:00 EST

Dr. Roy-Chaudhury will head up an organization--with nearly 21,000 health professionals representing 140 countries--dedicated to leading the fight against kidney diseases.

Researchers Test Imlifidase Enzyme Versus Plasma Exchange in Removing Donor-Specific Antibodies in Kidney Transplant Rejection Trial

American Society of Nephrology (ASN) — Sat, 26 Oct 2024 19:30:00 EST

For kidney transplant recipients experiencing antibody-mediated rejection, the current standard of care involves removing donor-specific antibodies (DSAs) through plasmapheresis (PLEX)--a procedure that removes antibodies from the plasma portion of the blood. Results from a recent clinical trial reveal that an investigational drug called imlifidase, which cleaves and inactivates the type of antibodies that include DSAs, is more effective than PLEX. The research will be presented at ASN Kidney Week 2024 October 23-27.

Preclinical Studies Test Novel Gene Therapy for Treating IgA Nephropathy

American Society of Nephrology (ASN) — Sat, 26 Oct 2024 19:30:00 EST

IgA nephropathy is an autoimmune kidney disease, and complement, a component of the innate immune system, plays a role in the condition's pathogenesis. Investigators have developed and tested a novel gene therapy that enters kidney cells and enables them to block complement activation. The research will be presented at ASN Kidney Week 2024 October 23- 27.

Trial Assesses Antibody Therapy for Chronic Active Antibody-Mediated Kidney Transplant Rejection

American Society of Nephrology (ASN) — Sat, 26 Oct 2024 19:30:00 EST

Chronic active antibody-mediated rejection (caAMR) is a common cause of allograft loss after transplantation, with no approved therapies. Clazakizumab, a monoclonal antibody that targets the inflammatory cytokine interleukin-6 (IL-6), stabilized kidney transplant recipients' kidney function in a phase 2 trial. Investigators now have data from a phase 3 trial with clazakizumab. The findings from the Phase 3 IMAGINE trial, the largest placebo-controlled study in kidney transplant recipients with caAMR, will be presented at ASN Kidney Week 2024 October 23- 27.

High-Impact Clinical Trials Generate Promising Results for Improving Kidney Health: Part 2

American Society of Nephrology (ASN) — Sat, 26 Oct 2024 13:30:00 EST

The results of numerous high-impact phase 3 clinical trials that could affect kidney-related medical care will be presented in-person at ASN Kidney Week 2024 October 23-27.

Researchers Integrate Multiple Protein Markers to Predict Health Outcomes in Individuals with Chronic Kidney Disease

American Society of Nephrology (ASN) — Fri, 25 Oct 2024 19:30:00 EST

Prior efforts to identify novel kidney biomarkers as risk factors for chronic kidney disease (CKD) progression have typically evaluated proteins individually, which limits their prognostic power. The National Institute of Diabetes and Digestive and Kidney Diseases' (NIDDK's) CKD Biomarkers Consortium of investigators recently developed and tested novel dimensions of kidney health by combining a set of 17 urine and plasma biomarkers that had been individually associated with CKD progression. The research will be presented at ASN Kidney Week 2024 October 23- 27.