News Feature Channel: Vaccines

Argonne to Explore Novel Ways to Fight Cancer and Transform Vaccine Discovery with Over $21 Million From ARPA-H

Argonne National Laboratory — Thu, 14 Nov 2024 14:35:19 EST

Argonne has received up to $21 million from ARPA-H to use AI and supercomputing in two projects: one targeting hard-to-treat tumors, and another aiming to create vaccines for multiple viral threats, including cancer and pandemics.

Community Partners Key to Success of Vaccine Clinic Focused on Neurodevelopmental Conditions

UC Davis MIND Institute — Wed, 13 Nov 2024 22:25:31 EST

Community partnerships led to a specialized clinic delivering COVID and flu shots to individuals with neurodevelopmental conditions like autism at the MIND Institute.

Vaccine Shows Promise Against Aggressive Breast Cancer

Washington University in St. Louis — Wed, 13 Nov 2024 20:00:00 EST

A small clinical trial shows promising results for patients with triple-negative breast cancer who received an investigational vaccine designed to prevent recurrence of tumors. Conducted at Washington University School of Medicine in St. Louis with a therapy designed by WashU Medicine researchers, the trial is the first to report results for this type of vaccine -- known as a neoantigen DNA vaccine -- for breast cancer patients.

Un avance hacia medicamentos y vacunas inhalables de ARNm

American Chemical Society (ACS) — Wed, 13 Nov 2024 13:15:37 EST

A la mayoria de la gente no le gusta aplicarse vacunas o inyecciones para recibir tratamientos. Por eso, los investigadores trabajan para crear mas medicamentos, como los que se fabrican a partir de ARN mensajero (ARNm), que puedan pulverizarse e inhalarse. Un estudio publicado en la revista Journal of the American Chemical Society informa sobre los avances para hacer posible los medicamentos de ARNm inhalables. Los investigadores indican que la nanoparticula de polimero lipidico, que es estable cuando se nebuliza y libera aerosoles (gotitas liquidas) en los pulmones de ratones de forma satisfactoria, se optimizo para contener el ARNm.

An Advance Toward Inhalable mRNA Medications, Vaccines

American Chemical Society (ACS) — Wed, 13 Nov 2024 08:00:00 EST

A study in the Journal of the American Chemical Society reports steps toward making inhalable mRNA medicines a possibility. Researchers outline their improved lipid-polymer nanoparticle for holding mRNA that is stable when nebulized and successfully delivers aerosols (liquid droplets) in mice's lungs.

Lab-Grown Human Immune System Uncovers Weakened Response in Cancer Patients

Georgia Institute of Technology — Tue, 12 Nov 2024 14:55:51 EST

These miniature immune system models -- known as human immune organoids -- mimic the real-life environment where immune cells learn to recognize and attack harmful invaders and respond to vaccines. Not only are these organoids powerful new tools for studying and observing immune function in cancer, their use is likely to accelerate vaccine development, better predict disease treatment response for patients, and even speed up clinical trials.

USU Researchers Develop Highly Effective Chlamydia Vaccine

Uniformed Services University of the Health Sciences (USU) — Tue, 12 Nov 2024 10:10:24 EST

Researchers from Uniformed Services University of the Health Sciences and Duke University have developed a promising vaccine offering strong protection against chlamydia. The study, published in npj Vaccines, shows that a whole-cell vaccine protected mice from infections, helping them clear the bacteria faster and with fewer infections, potentially reviving debates on chlamydia prevention.

World Pneumonia Day, Nov. 12: 2.2 Million Lives Lost to Pneumonia in 2021

American Thoracic Society (ATS) — Tue, 12 Nov 2024 09:25:13 EST

Urgent action is needed, to prevent pneumonia deaths among high-risk groups, particularly children younger than five years and older people, noted the American Thoracic Society and its Forum of International Respiratory Societies (FIRS) partners. New effective preventive interventions are available, but these are still inaccessible in many low- and middle-income countries (LMICs).

Cleveland Clinic Announces Updated Findings in Preventive Breast Cancer Vaccine Study

Cleveland Clinic — Fri, 08 Nov 2024 10:25:35 EST

Cleveland Clinic researchers are presenting updated findings from their novel study of a vaccine aimed at preventing triple-negative breast cancer, the most aggressive and lethal form of the disease. The study team found that the investigational vaccine was generally well tolerated and produced an immune response in most patients. The team described the side effects of the vaccine, showed the highest tolerated dose to date, and presented the immunologic effects of the vaccine. Findings are being presented at the Society for Immunotherapy of Cancer Annual Meeting.

Number of Whooping Cough Cases on Rise Nationally

Vanderbilt University Medical Center — Fri, 08 Nov 2024 09:15:07 EST

Whooping cough is making a comeback, and medical providers say the highly contagious bacterial infection that causes severe coughing fits is preventable. During the COVID-19 pandemic, whooping cough, also known as pertussis, declined dramatically.

Rutgers Study Reveals Vaccination Patterns Among LGBTQ+ Adults in New Jersey and New York

Rutgers University-New Brunswick — Tue, 05 Nov 2024 23:20:55 EST

A new study led by Rutgers Health researchers has uncovered important insights into vaccination patterns among LGBTQ+ adults in New Jersey and New York. The findings, published in the journal Vaccine, shed light on disparities in vaccine uptake within this diverse population.

Houston Methodist Researchers Shed Light on Increased Rates of Severe Human Infections Caused by Streptococcus Subspecies

Houston Methodist — Fri, 01 Nov 2024 16:00:11 EST

A concerning increase in global rates of severe invasive infections becoming resistant to key antibiotics has a team of infectious disease researchers at the Houston Methodist Research Institute studying a recently emerged strain of bacteria called Streptococcus dysgalactiae subspecies equisimilis (SDSE). SDSE infects humans via the skin, throat, gastrointestinal tract and female genital tract to cause infections ranging in severity from strep throat (pharyngitis) to necrotizing fasciitis (flesh-eating disease).

Steps You Can Take to Reduce Your Risk for Liver Cancer

University of Kentucky — Fri, 01 Nov 2024 10:25:09 EST

Liver cancer is the sixth leading cause of cancer death in the U.S. The most common type of liver cancer in adults is hepatocellular carcinoma, and men are more likely to develop HCC than women. It typically develops in people with long-lasting liver disease caused by hepatitis virus infection or cirrhosis. In many cases, liver cancer is a preventable cancer, so raising awareness about prevention is important.

MD Anderson Research Highlights for October 30, 2024

University of Texas MD Anderson Cancer Center — Wed, 30 Oct 2024 12:00:04 EST

The University of Texas MD Anderson Cancer Center's Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson's world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.

Update: San Diego scientist available to comment on dengue vaccine research -- following report of second locally transmitted dengue case

La Jolla Institute for Immunology — Tue, 29 Oct 2024 12:25:35 EST

Vaccine Refusal Lower in Minorities in New Study

American College of Allergy, Asthma and Immunology (ACAAI) — Thu, 24 Oct 2024 08:00:00 EST

Throughout the Covid pandemic, media widely reported that Black patients were more likely than White patients to refuse vaccines, including the influenza and Covid vaccines. A new study being presented at this year's American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting in Boston showed that self-identified non-White patients were less likely to demonstrate vaccine-hesitancy than the self-identified White patient group.

Segun un nuevo estudio, el rechazo a las vacunas es menor entre las minorias

American College of Allergy, Asthma and Immunology (ACAAI) — Thu, 24 Oct 2024 08:00:00 EST

Durante la pandemia de COVID, los medios informaron ampliamente que los pacientes negros tenian mas probabilidades que los pacientes blancos de rechazar las vacunas, incluidas las vacunas contra la influenza y el COVID. Un nuevo estudio que se presentara en la Reunion Cientifica Anual del Colegio Americano de Alergia, Asma e Inmunologia (ACAAI) de este ano en Boston mostro que los pacientes que se identifican como no blancos tenian menos probabilidades de mostrar desconfianza en cuando a las vacunas que los pacientes que se identifican como blancos.

KU Cancer Center Leads National Trial Testing Vaccine for Colon Cancer in People with Lynch Syndrome

University of Kansas Cancer Center — Wed, 23 Oct 2024 14:35:46 EST

A researcher at The University of Kansas Cancer Center is leading a national clinical trial to test a combination vaccine to prevent colon cancer in people with Lynch syndrome.

Surprising Reason That B Cells Benefit From Booster Shots

Rockefeller University — Wed, 23 Oct 2024 12:55:03 EST

Certain infectious diseases, such as COVID or the flu, evolve constantly, shapeshifting just enough to outmaneuver our immune systems and reinfect us repeatedly. But subsequent reinfections often don't lead to the most severe outcomes--for very good reason. Upon first exposure to a pathogen, our immune systems churn out specially trained B cells, which have learned to identify and eliminate the virus.

West Nile Infections Are Spiking. Here's Why the Percentage of Severe Cases Is So Small

Rockefeller University — Wed, 23 Oct 2024 12:45:09 EST

The U.S. is currently in the midst of yet another West Nile virus (WNV) outbreak, with the CDC documenting 880 cases across 46 states so far this year.