News Feature Channel: Digestive Disorders

UTEP Researchers Develop Portable, Blood-Based Device that Detects Colon Cancer

University of Texas at El Paso — Thu, 13 Mar 2025 20:50:01 EST

Scientists at The University of Texas at El Paso are developing a less invasive portable device that would use blood samples to detect colorectal cancers. Their device is described in a new study published in the journal ACS Measurement Science Au.

Mayo Clinic Researchers Identify Proteins Linked to Immunotherapy Resistance in Metastatic Colorectal Cancer

Mayo Clinic — Thu, 13 Mar 2025 20:45:38 EST

A discovery by Mayo Clinic researchers may help explain why immunotherapy hasn't been helpful for many patients with metastatic colorectal cancer. In findings published in Clinical Cancer Research, the team identified specific proteins -- fibronectin and smooth muscle actin -- within colorectal cancer tissues that are associated with resistance to immunotherapy treatment.

New Guideline on Gastric Premalignant Cancer Published by the American College of Gastroenterology

American College of Gastroenterology (ACG) — Wed, 12 Mar 2025 19:50:37 EST

The American College of Gastroenterology has published its first clinical guideline on the diagnosis and management of gastric premalignant conditions (GPMC), including endoscopic surveillance, risk stratification, resection, the role of H. pylori infection, risk reduction, and management of autoimmune gastritis and gastric epithelial polyps.

GLP-1 Use Before Endoscopy, Resuming Blood Thinners after ESD, and More in the March Issue of AJG

American College of Gastroenterology (ACG) — Mon, 10 Mar 2025 19:35:02 EST

In the March issue of The American Journal of Gastroenterology: The effect of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) on gastric retention before endoscopy, resumption of blood thinners after colorectal submucosal dissection, and the utility of inpatient GI consults to clear patients for transesophageal echocardiogram.

What Women Need to Know About Colorectal Cancer

Rutgers Cancer Institute — Mon, 10 Mar 2025 17:25:34 EST

Colorectal cancer is the third leading cause of cancer-related deaths in women, and approximately 1 in 26 women will be diagnosed with colorectal cancer in her lifetime. Awareness about risk factors and early detection are crucial in preventing and effectively treating colorectal cancer.

Wireless Ingestible Capsule Detects 'Leaky Gut' in Real-Time

Chinese Academy of Sciences — Mon, 10 Mar 2025 08:45:30 EST

A team of researchers has unveiled a revolutionary ingestible bioimpedance sensing device capable of continuously and non-invasively monitoring the integrity of gastrointestinal (GI) mucosal barriers. This pioneering technology overcomes a major limitation in current diagnostic tools, which cannot assess the condition of mucosal tight junctions beyond the esophagus.

A Glass of Milk, A Roasted Sweet Potato, an Apple a Day - Could These Everyday Foods Protect Against Colorectal Cancer?

Hackensack Meridian Health — Mon, 10 Mar 2025 08:40:10 EST

Can a Little-Known Cell Type Lead to New Treatments for IBD?

Children's Hospital Los Angeles — Fri, 07 Mar 2025 19:10:05 EST

For decades, the goal of treating inflammatory bowel disease (IBD) has been to control the aggressive inflammation that attacks the colon. Although anti-tumor necrosis factor (TNF) therapies have helped to better manage this inflammation in recent years, up to 70% of patients don't respond to these drugs long-term. But what if there was a different way to attack IBD--one that did not involve targeting inflammation? This is the work that Michael Schumacher, PhD, is leading in his lab at Children's Hospital Los Angeles.

ARUP Laboratories Expands AI-Augmented Parasitology Screening Tool, Improves Detection and Diagnosis

ARUP Laboratories — Thu, 06 Mar 2025 10:55:36 EST

Adiso Therapeutics Announces Data Publication of Two Phase 1 Studies of First-in-Class Neutrophil Modulator ADS051 in the American Journal of Gastroenterology

Adiso Therapeutics — Thu, 06 Mar 2025 07:05:51 EST

Adiso Therapeutics, Inc. announced the publication of the results of two Phase 1 studies, which showed that healthy subjects and ulcerative colitis (UC) patients given oral doses of ADS051, a novel modulator of neutrophils being developed for Inflammatory Bowel Disease (IBD), could be safely administered and well-tolerated in IBD patients.

ACG Champions the Importance of Preventive Care and Colorectal Cancer Screening in Supreme Court Amicus Brief

American College of Gastroenterology (ACG) — Wed, 05 Mar 2025 19:20:09 EST

ACG represented the interests of GI clinicians and patients before the nation's highest court, ensuring the Supreme Court justices recognize their decision in Kennedy v. Braidwood could erase decades of progress in colorectal cancer prevention and screening.

Neurosurgeon Raises NIH Funding Concerns in Key Letter

UC San Diego Health — Wed, 05 Mar 2025 19:10:57 EST

4 Things to Know about the Rise of Colorectal Cancer in Younger Adults

American College of Surgeons (ACS) — Tue, 04 Mar 2025 18:15:45 EST

For Colorectal Cancer Awareness Month, experts with the American College of Surgeons are available for media interviews to share insights into why the disease is affecting more younger adults, and what can be done to prevent it.

NIH Provides Critical Funding for Pediatric Clinical Trials in Diseases Not Prioritized by Industry, Study Shows

Ann and Robert H. Lurie Children's Hospital of Chicago — Tue, 04 Mar 2025 16:45:58 EST

"We observed that NIH funded key research areas that are less often prioritized by industry, and this is critical for establishing new treatments that children need," said lead author Ansh...

Evidence-Based Strategies Improve Colonoscopy Bowel Preparation Quality, Performance, and Patient Experience

American College of Gastroenterology (ACG) — Tue, 04 Mar 2025 09:00:00 EST

Updated consensus recommendations by the U.S. Multi-Society Task Force on Colorectal Cancer (MSTFCRC) address optimizing bowel preparation quality for colonoscopy. Highlights include the use of low volume bowel preparation and the adjunctive use of simethicone.

Cleveland Clinic Develops Prediction Score to Estimate Risk of Early-Onset Colorectal Cancer and Precancerous Polyps

Cleveland Clinic — Mon, 03 Mar 2025 08:30:51 EST

Cleveland Clinic researchers developed and validated a prediction model that estimates the risk of developing colorectal cancer and advanced precancerous polyps in adults under 45 years old. The paper was published in Digestive Diseases and Sciences

More Than a Gut Feeling: How Climate Change Affects GI Health

Michigan State University — Thu, 27 Feb 2025 19:15:24 EST

More than a gut feeling: How climate change affects GI health

The Invisible Complication: Experts at ACS Summit Address Surgical Adhesions and Their Hidden Costs

American College of Surgeons (ACS) — Thu, 27 Feb 2025 11:00:00 EST

A group of international experts convened in Washington, D.C., in September 2024 for the American College of Surgeons (ACS) Surgical Adhesions Improvement Project Summit to explore the challenges of surgical adhesions in depth and identify future solutions. Proceedings from the Summit are published in the Journal of the American College of Surgeons.

Colorectal Cancer on the Rise in Younger Adults: One Woman's Journey during Pregnancy

Hackensack Meridian Health — Thu, 27 Feb 2025 10:50:55 EST

Colorectal cancer incidence rates continue to rise in those under age 50 -- a trend that underscores the need for increased awareness and early detection. During this Colorectal Cancer Awareness Month, experts from Hackensack Meridian Health are available to discuss this trend, along with a patient diagnosed with CRC at age 37 while pregnant.

ASTRO Issues Its First Clinical Guideline on Radiation Therapy for Anal Cancer

American Society for Radiation Oncology (ASTRO) — Thu, 27 Feb 2025 09:05:04 EST

A new clinical guideline from the American Society for Radiation Oncology (ASTRO) provides guidance on the use of radiation therapy to treat adult patients with primary squamous cell carcinoma (SCC) of the anal canal and anal margin. The guideline, ASTRO's first for anal cancer, is published in Practical Radiation Oncology.