News Feature Channel: Blood

Preventing and Recognizing Blood Clots

Children's Hospital Los Angeles — Wed, 05 Mar 2025 06:00:32 EST

When you hear the condition "blood clot," your mind may not immediately think of your child being at risk. But Guy Young, MD, Director of the Hemostasis and Thrombosis Center at Children's Hospital Los Angeles, says he's seen a recent uptick of patients suffering from blood clots."Our team treats roughly four new pediatric patients with blood clots each week," says Dr.

NIH Provides Critical Funding for Pediatric Clinical Trials in Diseases Not Prioritized by Industry, Study Shows

Ann and Robert H. Lurie Children's Hospital of Chicago — Tue, 04 Mar 2025 16:45:58 EST

"We observed that NIH funded key research areas that are less often prioritized by industry, and this is critical for establishing new treatments that children need," said lead author Ansh...

VUMC Part of New Study Validating Curative Therapy for Sickle Cell Disease

Vanderbilt University Medical Center — Tue, 04 Mar 2025 10:50:20 EST

A modified bone marrow transplant procedure for sickle cell disease (SCD) co-developed at Vanderbilt University Medical Center, Johns Hopkins University School of Medicine, and the University of California, San Francisco, can cure the disease, a new study has found.

Cryo-EM Technology Reveals How Vitamin K Works in the Body

UT Southwestern Medical Center — Tue, 04 Mar 2025 10:45:24 EST

Using a powerful microscopy technique, a team led by researchers at UT Southwestern Medical Center has gained insights into how the body uses vitamin K, an essential nutrient that plays a pivotal role in blood clotting and other physiological functions.

Mount Sinai Researchers Identify Molecular Glues That Protect Insulin-Producing Cells From Damage Related to Diabetes

Mount Sinai Health System — Tue, 04 Mar 2025 10:00:06 EST

Findings could improve long-term outcomes for patients

Unlocking a New Path to AML Treatment: Targeting the JMJD1C-RUNX1 Axis for Leukemia Progression Control

Chinese Academy of Sciences — Mon, 03 Mar 2025 05:55:10 EST

A new study has identified a critical mechanism that could lead to substantial advancements in the treatment of acute myeloid leukemia (AML). Researchers have discovered that the protein JMJD1C plays a pivotal role in leukemia cell survival. Specifically, JMJD1C is recruited by RUNX1 to genomic loci, where it forms liquid-like condensates.

Blood Test Could Lead to Better Diagnosis and Management of ALS

American Academy of Neurology (AAN) — Wed, 26 Feb 2025 16:00:00 EST

ALS, or amyotrophic lateral sclerosis, can sometimes be difficult to diagnose or to predict how quickly the disease is likely to progress. A new study helps determine which blood tests are best at identifying and monitoring ALS. The study is published in the February 26, 2025, online issue of Neurology(r), the medical journal of the American Academy of Neurology.

New Technique Reveals How the Same Mutations Give Rise to Very Different Types of Leukaemia

Fundacio Institut de Recerca Biomedica (IRB BARCELONA) — Tue, 25 Feb 2025 18:20:00 EST

* A study from IRB Barcelona, funded by Fundacion CRIS contra el cancer demonstrates that the "previous state" of blood stem cells plays a decisive role in the subtype of leukaemia that develops. * The new technique, called STRACK, allows monitoring of the evolution of each cell before and after acquiring oncogenic mutations.

New Study Raises Alarm Over Alzheimer's Blood Tests

Rutgers University-New Brunswick — Tue, 25 Feb 2025 09:40:44 EST

Rutgers Health researchers find that the diagnostic tools can be unreliable, particularly for Black patients.

New Paper-based Device Boosts HIV Test Accuracy From Dried Blood Samples

Tufts University — Mon, 24 Feb 2025 20:35:48 EST

Researchers engineered a paper device with wax-printed patterns that collect precise volumes of blood, which can be used for sample collection at remote locations across the globe. A clinical pilot demonstrated significantly improved detection of HIV over current standard methods.

UM School of Medicine Dermatology Researchers Discover New Skin Disease Using Innovative Diagnostic Platform

University of Maryland School of Medicine — Mon, 24 Feb 2025 19:35:19 EST

UM School of Medicine Dermatology Researchers Discover New Skin Disease Using Innovative Diagnostic Platform

Uncovering Genetic Links to the Risk of Heart Disease and Diabetes in South Africa

University of Pretoria — Mon, 24 Feb 2025 07:30:12 EST

Prof. Alisa Phulukdaree, newly appointed full professor, highlights the urgent need for genetic research on cardiovascular disease & Type 2 diabetes in South Africa. Her work is paving the way for personalized medicine that addresses the unique genetic diversity of the population.

Even 'Normal' Blood Sugar Levels May Raise Heart Risk, according to UCLA Health Experts

University of California, Los Angeles (UCLA), Health Sciences — Fri, 21 Feb 2025 17:25:31 EST

Current guidelines around healthy blood glucose levels may need a re-think, according to UCLA Health experts, as research shows that patients with blood sugar levels on the higher side of "normal" are associated with a notable increased risk of cardiovascular disease.

Frequent Nosebleeds? It Could Be HHT, a Serious but Treatable Genetic Disorder

UT Southwestern Medical Center — Thu, 20 Feb 2025 20:20:47 EST

For patients with hereditary hemorrhagic telangiectasia (HHT), frequent and sometimes intense nosebleeds are a regular occurrence. HHT, also called Osler-Weber-Rendu syndrome, is a genetic bleeding disorder that causes abnormal development of capillaries, the tiny vessels that connect our arteries and veins.

Vital Sign Accuracy May Depend on Body Position, Research Suggests

American Physiological Society (APS) — Thu, 20 Feb 2025 07:00:05 EST

Body position can affect the accuracy of vital sign measurements that indicate arterial stiffness--a risk factor for heart disease--according to new research. Sitting down during certain tests may cause a spike in arterial stiffness readings that does not reflect a true increase.

Ticagrelor Monotherapy Associated with Lower Risk of Bleeding, Without Increase in Ischemic Events Than Standard Dual Antiplatelet Therapy in Patients with Acute Coronary Syndrome

American College of Physicians (ACP) — Mon, 17 Feb 2025 17:00:00 EST

A systematic review and meta-analysis compared the efficacy and safety of de-escalating dual antiplatelet therapy (DAPT) to ticagrelor monotherapy versus standard DAPT in patients with acute coronary syndrome (ACS) undergoing drug-eluting stint (DES).

New Lipid Nanoparticle Platform Delivers mRNA to the Brain Through the Blood-Brain Barrier

Mount Sinai Health System — Mon, 17 Feb 2025 05:00:00 EST

Scientists at the Icahn School of Medicine at Mount Sinai have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection, a challenge that has long been limited by the protective nature of the blood-brain barrier. The findings, in mouse models and isolated human brain tissue, were published in the February 17 online issue of Nature Materials [10.1038/s41563-024-02114-5]. They demonstrate the potential of this technology to pave the way for future treatments for a wide range of conditions such as Alzheimer's disease, amyotrophic lateral sclerosis, brain cancer, and drug addiction.

Evolutionary Tradeoffs: Research Explores the Role of Iron Levels in COVID-19 Infections

Binghamton University, State University of New York — Thu, 13 Feb 2025 21:35:25 EST

Our immune systems rely on iron to function, but so do invading viruses and bacteria. New research from Binghamton University, State Univerity of New York studying healthcare workers in Nigeria during COVID, reveals that very early in the arms race -- when an infectious disease is emerging and still very new to humans -- iron nutrition tradeoffs are in play.

New Blood-Clotting Disorder Identified by McMaster University Researchers

McMaster University — Wed, 12 Feb 2025 17:00:00 EST

Researchers at McMaster University have made a groundbreaking discovery in the field of hematology, providing an explanation for spontaneous and unusual blood-clotting that continues to occur despite treatment with full-dose blood thinners.

Bleeding Risk with Apixaban and Dabigatran Similar to Aspirin

American College of Physicians (ACP) — Mon, 10 Feb 2025 17:00:00 EST

A systematic review and meta-analysis estimating the differences in bleeding risks between therapeutic-dose non-vitamin K oral anticoagulants (NOACs) and single antiplatelet therapy (aspirin) found that rates of major bleeding for therapeutic-dose apixaban and dabigatran were similar to low-dose aspirin, but rates were higher for rivaroxaban.