News Curated �鶹��ý Channel: Grant Funded News

New Study Shows How Salmonella Tricks Gut Defenses to Cause Infection

UC Davis Health — Fri, 15 Nov 2024 16:30:58 EST

A study led by UC Davis distinguished professor Andreas Baumler uncovered how Salmonella, a major cause of food poisoning, can invade the gut despite the presence of protective bacteria.

Study Challenges Assumptions About How Tuberculosis Bacteria Grow

Tufts University — Fri, 15 Nov 2024 14:50:59 EST

The rod-shaped tuberculosis (TB) bacterium, which the World Health Organization has once again ranked as the top infectious disease killer globally, is the first single-celled organism ever observed to maintain a consistent growth rate throughout its life cycle. These findings, reported by researchers on November 15 in the journal Nature Microbiology, overturn core beliefs of bacterial cell biology and hint at why the deadly pathogen so readily outmaneuvers our immune system and antibiotics.

"We Need Everyone": New Award Recognizes the Importance of Scientific Community

University of Utah Health — Wed, 13 Nov 2024 13:30:03 EST

In the lab of Minna Roh-Johnson, PhD, great science and great mentorship are inextricable. Now, up to $250,000 in federal funding from the National Cancer Institute has made that philosophy concrete by advancing cancer research and building scientific community.

New Research Highlights Potential Role of the Thalamus in Complex Reasoning

Tufts University — Wed, 13 Nov 2024 11:00:00 EST

Human Stem Cell-Derived Heart Cells Are Safe in Monkeys, Could Treat Congenital Heart Disease

University of Wisconsin-Madison — Wed, 13 Nov 2024 09:55:36 EST

Heart muscle cells grown from stem cells show promise in monkeys with a heart problem that typically results from a heart defect sometimes present at birth in humans, according to new research from the University of Wisconsin-Madison and Mayo Clinic.

On the Origin of Life: How the First Cell Membranes Came to Exist

University of California San Diego — Wed, 13 Nov 2024 08:00:00 EST

Few questions have captivated humankind more than the origin of life on Earth. How did the first living cells come to exist? How did these early protocells develop the structural membranes necessary for cells to thrive and assemble into complex organisms? New research from UC San Diego has uncovered a plausible explanation involving the reaction between two simple molecules.

AI Needs to Work on Its Conversation Game

Tufts University — Tue, 12 Nov 2024 05:40:53 EST

Linguistics and computer science researchers at Tufts University have discovered some of the root causes of the inability of AI to engage in human-like conversation

Study: Online E-Cigarette Retailers Fail to Comply with Sale Regulations

University of California San Diego — Mon, 11 Nov 2024 11:00:00 EST

Online e-cigarette retailers are not consistently adhering to laws aimed at preventing the sale of vaping products to minors, including regulations on age verification, shipping methods and flavor restrictions, report researchers at the Herbert Wertheim School of Public Health and Human Longevity Science at University of California San Diego.

New Material to Make Next Generation of Electronics Faster and More Efficient

University of Minnesota College of Science and Engineering — Fri, 08 Nov 2024 08:00:10 EST

Researchers at the University of Minnesota have achieved a new material that will be pivotal in making the next generation of high-power electronics faster, transparent and more efficient.

Researchers Make Glioblastoma Cells Visible to Attacking Immune Cells

Washington University in St. Louis — Thu, 07 Nov 2024 13:15:09 EST

Researchers at WashU Medicine have identified a possible way to make glioblastoma cells vulnerable to different types of immunotherapy. The strategy, which they demonstrated in cells in the lab, forces brain cancer cells to display targets for the immune system to attack. Their study was published in Nature Genetics.

Researchers Find Metabolic Mechanism That Blocks Immune Response, Immunotherapy in Cancer

Michigan Medicine - University of Michigan — Thu, 07 Nov 2024 11:50:30 EST

Researchers at the University of Michigan Rogel Cancer Center have discovered a key reason why some cancers do not respond to immunotherapy: A metabolite transporter within the tumor microenvironment that blocks a key type of tumor cell death integral to immune response.

People with Schizophrenia Show Distinct Brain Activity When Faced with Conflicting Information

Tufts University — Thu, 07 Nov 2024 11:00:00 EST

In a study published November 7 in the journal Cell Reports Medicine, researchers from Tufts University School of Medicine and Vanderbilt University School of Medicine show that people with schizophrenia generate distinct neural patterns when asked to make decisions based on conflicting information. The work offers one of the first biological tests to assess whether someone is prone to inflexible thinking and, by monitoring changes in these patterns, a new way to measure whether treatments are working.

How Plants Evolved Multiple Ways to Override Genetic Instructions

Washington University in St. Louis — Wed, 06 Nov 2024 14:00:00 EST

WashU biologists, led by Xuehua Zhong in Arts & Sciences, investigated the inner workings of DNA methylation in plants. Their findings could help engineer crops that are more resilient to environmental changes, like heat or drought stress.

How Hypoxia Helps Cancer Spread

Johns Hopkins Medicine — Tue, 05 Nov 2024 11:30:21 EST

Scientists at the Johns Hopkins Kimmel Cancer Center have identified 16 genes that breast cancer cells use to survive in the bloodstream after they've escaped the low-oxygen regions of a tumor. Each is a potential therapeutic target to stop cancer recurrence, and one - MUC1 - is already in clinical trials.

Ensuring a Bright Future for Diamond Electronics and Sensors

Princeton Plasma Physics Laboratory — Tue, 05 Nov 2024 08:30:47 EST

To expand the potential use of diamond in semiconductor and quantum technologies, researchers are developing improved processes for growing the material at lower temperatures that won't damage the silicon in computer chips. These advances include insights into creating protective hydrogen layers on quantum diamonds without damaging crucial properties like nitrogen-vacancy centers.

Explaining Science Through Dance

University of California San Diego — Tue, 05 Nov 2024 05:00:00 EST

Science can be difficult to explain to the public. Explaining a theoretical science concept to high school students requires a new way of thinking altogether, which is precisely what researchers at UC San Diego did when they orchestrated a dance with high school students at Orange Glen High School in Escondido as a way to explain topological insulators. The experiment was led by former graduate student Matthew Du and UC San Diego Associate Professor of Chemistry and Biochemistry Joel Yuen-Zhou.

Moffitt Study Links Methylmalonic Acid to Weakening of Immune Cells in Lung Cancer

Moffitt Cancer Center — Thu, 31 Oct 2024 14:05:32 EST

A new study has found a surprising link between high levels of methylmalonic acid and the weakening of CD8+ T cells, shedding light on potential pathways through which aging may promote lung cancer progression. Moffitt Cancer Center researchers have found new insights into how metabolic changes associated with aging can impact immune responses against tumors.

Researchers Solve Medical Mystery of Neurological Symptoms in Kids

Washington University in St. Louis — Thu, 31 Oct 2024 14:00:00 EST

Researchers at WashU Medicine collaborated with an international team of doctors and scientists to identify the cause of a rare disorder involving intellectual disability and brain malformations. The team found a link between the child's neurological symptoms and a genetic change that affects how proteins are properly folded within cells, providing the parents with a molecular diagnosis and identifying an entirely new type of genetic disorder. The findings are published in Science.

ARC Launches Clinical Fellowship Program to Advance Amyloidosis Care

Amyloidosis Research Consortium — Thu, 31 Oct 2024 09:20:42 EST

The Amyloidosis Research Consortium (ARC) is proud to announce the launch of its Clinical Fellowship Program, designed to enhance the education and development of the next generation of amyloidosis specialists.

Wearable Ultrasound Tech for Muscle Monitoring Opens New Possibilities in Healthcare and Human-Machine Interfaces

University of California San Diego — Thu, 31 Oct 2024 06:00:00 EST

Researchers have developed a compact, wearable ultrasound device that monitors muscle activity. Attachable to the skin with an adhesive and powered by a small battery, the device wirelessly captures high-resolution images of muscle movements, enabling continuous, long-term monitoring. When worn on the rib cage, it effectively monitored diaphragm function for respiratory health assessments. When worn on the forearm, it accurately captured hand gestures, allowing users to control a robotic arm and even navigate virtual games. This new technology has potential applications in healthcare for conditions affecting muscle function, as well as in human-machine interfaces for more natural robotic control.