News Feature Channel: Liver Disease

Cancer Management: Stent Sensor Can Warn of Blockages in the Bile Duct

University of Michigan — Thu, 31 Oct 2024 11:40:45 EST

Stents to treat various blockages in the human body can themselves become blocked, but a new sensor developed at the University of Michigan for stents that are used in the bile duct may one day help doctors detect and treat stent blockages early, helping keep patients healthier.

Enhancing the Functionality of Mesenchymal Stem Cells: An Attractive Treatment Strategy for Metabolic Dysfunction-Associated Steatotic Liver Disease?

World Journal of Stem Cells — Wed, 30 Oct 2024 12:00:36 EST

The intrinsic heterogeneity of metabolic dysfunction-associated fatty liver disease (MASLD) and the intricate pathogenesis have impeded the advancement and clinical implementation of therapeutic interventions, underscoring the critical dema

Cedars-Sinai Researchers Reverse Liver Fibrosis in Mice

Cedars-Sinai — Wed, 30 Oct 2024 11:05:06 EST

New research led by Cedars-Sinai investigators has reversed liver fibrosis, a gradual buildup of scar tissue in the liver, in laboratory mice. Their achievement marks a crucial step toward potentially creating new treatments for patients with this condition, which can lead to life-threatening diseases including cirrhosis, liver failure and liver cancer.

Antibody Shows Promise Against Obesity-related Liver Disease and Atherosclerosis in Mice

Federation of American Societies for Experimental Biology (FASEB) — Mon, 28 Oct 2024 15:50:39 EST

Latest research in the FASEB Journal reveals an antibody called bFKB1 improves liver disease and atherosclerosis in a mouse model of metabolic dysfunction-associated steatohepatitis (MASH), which is associated with obesity.

Enhancing the Functionality of Mesenchymal Stem Cells: An Attractive Treatment Strategy for Metabolic Dysfunction-Associated Steatotic Liver Disease?

World Journal of Stem Cells — Mon, 28 Oct 2024 12:00:18 EST

Enhancing the Functionality of Mesenchymal Stem Cells: An Attractive Treatment Strategy for Metabolic Dysfunction-Associated Steatotic Liver Disease?

World Journal of Stem Cells — Sat, 26 Oct 2024 12:00:20 EST

Enhancing the functionality of mesenchymal stem cells: An attractive treatment strategy for metabolic dysfunction-associated steatotic liver disease?

World Journal of Stem Cells — Sat, 26 Oct 2024 12:00:19 EST

Enhancing the Functionality of Mesenchymal Stem Cells: An Attractive Treatment Strategy for Metabolic Dysfunction-Associated Steatotic Liver Disease?

World Journal of Stem Cells — Sat, 26 Oct 2024 12:00:16 EST

Mayo Clinic Performs Its First Paired Living Liver Donation

Mayo Clinic — Wed, 23 Oct 2024 10:50:17 EST

Surgeons recently performed Mayo Clinic's first paired living liver donation, a significant first step in helping more people with liver failure get a lifesaving transplant.

How Liver Tissue from the International Space Station may Transform Tissue Engineering

American College of Surgeons (ACS) — Fri, 18 Oct 2024 08:00:00 EST

An "out-of-this-world" project has the potential to transform the future of tissue engineering and liver transplantation through innovative research conducted aboard the International Space Station (ISS).

Custom Alterations: Mending Genes for Long-Lasting Effects

National Institute of Biomedical Imaging and Bioengineering — Thu, 17 Oct 2024 11:00:03 EST

NIBIB-funded researchers are working to bring in vivo gene editing to the fore. Through rational engineering of lipid nanoparticles, this collaborative team developed a way to effectively target specific organs in the body to precisely deliver therapeutic cargo, including gene-editing molecules.

A Decade of Successful Outcomes: Corewell Health's Liver Transplant Program in Southeast Michigan Nationally Recognized

Corewell Health — Thu, 10 Oct 2024 12:05:46 EST

The liver transplant program at Corewell Health in Southeast Michigan consistently ranks among the highest quality liver transplant programs in Michigan and the nation, according to federal quality data.

Study Shows Changes to Organ Allocation Policy Reduced Waiting Time and Increased Transplants for Children With Pediatric Acute Liver Failure

Children's Hospital Los Angeles — Thu, 03 Oct 2024 12:05:51 EST

The Organ Procurement and Transplantation Network (OPTN) has periodically revamped its organ allocation policies over the years to prioritize sicker children over adults and expand the geographic area of donors. A recent study led by Children's Hospital Los Angeles showed that this has helped improve the odds for children with PALF.

From Replicant's Dream to Reality: Imaging AI Extending Lives

Perelman School of Medicine at the University of Pennsylvania — Wed, 02 Oct 2024 10:05:28 EST

A new AI tool is providing a sci-fi level of precision to physicians reviewing images of people's livers, spleens, kidneys, and more to determine with some exactitude if they are showing any abnormal traits that could shorten a person's life

UTSW Research: Alcohol-Associated Liver Disease, Depression Treatment, and More

UT Southwestern Medical Center — Thu, 26 Sep 2024 13:05:29 EST

Research roundup: How alcohol-associated liver disease differs among races; Esketamine shows promise for treatment-resistant depression; COVID-19's effects on individual employment; EEG testing shows possible biomarker for suicidal ideation

Innovative Mesenchymal Stem Cell Treatments for Fatty Liver Disease

World Journal of Stem Cells — Thu, 26 Sep 2024 12:00:43 EST

The incidence of non-alcoholic fatty liver disease (NAFLD) and alcohol-associated liver disease (ALD) is increasing year by year due to changes in the contemporary environment and dietary structure, and is an important public health problem

Histotripsy Liver Tumor Trial Successful, Early Clinical Adoption Recommended

Michigan Medicine - University of Michigan — Tue, 24 Sep 2024 10:30:28 EST

The #HOPE4LIVER trials, testing the safety efficacy of histotripsy as a treatment for primary and metastatic liver tumors, met its goals for technical success and safety. An expert is quoted explaining the results.

Patients with Alcohol Use Disorder at Risk of Liver Disease May be Less Commonly Referred for Liver Treatment if they are primarily seen for Mental Health Disorders

Research Society on Alcoholism — Sat, 21 Sep 2024 10:00:00 EST

People with alcohol use disorder (AUD) who are at risk of advanced liver disease are less likely to be referred for liver evaluation and care if they present primarily with alcohol-related mental health issues or a mental health diagnosis, according to a study of referral practices in Virginia's largest health system. The findings point to the possibility of widespread missed opportunities for treating three conditions that commonly co-occur: AUD, mental health disorders, and liver disease. Recent years have seen notable increases in the USA in alcohol-related deaths, mental health disorders, and hospital admissions relating to alcohol use and concurrent mental health conditions. AUD is a significant cause of liver disease, and both addiction and co-occurring mental illness can be barriers to successful liver treatment. Integrating AUD treatment, mental health care, and hepatology (liver care) is necessary to improve outcomes, but data suggests this approach is not the norm. For the st

Could Your Phone Detect Hepatic Encephalopathy by Listening to You Read?

Michigan Medicine - University of Michigan — Wed, 18 Sep 2024 13:00:01 EST

Research from the University of Michigan suggests that one day a phone app could be able to detect the development of hepatic encephalopathy in patients just by listening to them speak.

What is Liver Transplant Rejection?

Children's Hospital Los Angeles — Tue, 17 Sep 2024 11:05:47 EST

Receiving a liver transplant means also living with the possibility of rejection. Transplant rejection occurs when the body's immune system attacks the new organ. This risk is highest in the first year after the transplant, but rejection can happen at any time. To prevent this, patients take powerful medications to suppress their immune system and reduce inflammation.