News Feature Channel: Clinical Trials

Baltimore Student-Athlete Is Winning Match Against Multiple Sclerosis

Johns Hopkins Medicine — Thu, 27 Mar 2025 18:05:46 EST

Gabryelle "Gabby" Scholfield, a 16-year-old student-athlete at Edmondson Westside High School in Baltimore, who plays center on her basketball team, is known for getting rebounds on the basketball court. However, only about a year ago, she was rebounding from serious complications of multiple sclerosis (MS).

Engenheiros de manufatura da Mayo Clinic estao prestes a entregar novas bioterapias

Mayo Clinic — Thu, 27 Mar 2025 10:20:24 EST

Engenheiros de manufatura estao na vanguarda de trazer novos medicamentos derivados de fontes humanas, como celulas, sangue e genes, para os pacientes. Eles produzem o que muitas vezes sao bioterapias pioneiras do seu tipo para doencas que anteriormente tinham poucas ou nenhuma opcao de tratamento.

Mayo Clinic Manufacturing Engineers on the Cusp of Delivering New Biotherapies

Mayo Clinic — Thu, 27 Mar 2025 09:45:05 EST

Manufacturing engineers are at the forefront of bringing new medicines derived from human sources such as cells, blood and genes to patients. They produce what are often first-of-their kind biotherapies for diseases that previously had few or no treatment options.

Ingenieros de manufactura de Mayo Clinic estan a punto de entregar nuevas bioterapias

Mayo Clinic — Thu, 27 Mar 2025 09:15:05 EST

JACKSONVILLE, Florida -- Ingenieros de manufactura estan a la vanguardia de llevar nuevos medicamentos derivados de fuentes humanas, como celulas, sangre y genes, a los pacientes. Ellos producen lo que a menudo son bioterapias pioneras de su tipo para enfermedades que anteriormente tenian pocas o ninguna opcion de tratamiento.

NIH-Funded Trial Studies if Wearables Can Reduce the Need for Continuous Blood Thinners for Patients with Atrial Fibrillation

Northwestern Medicine — Thu, 27 Mar 2025 08:20:09 EST

Atrial fibrillation (AFib) is the most common type of heart arrhythmia impacting more than 5 million people in the United States, a number that is anticipated to reach 12.1 million by 2030. The heart rhythm condition is characterized by fast and irregular heartbeats from the upper chambers of the heart. People with AFib are at increased risk of stroke, heart failure, dementia, and premature death.

مهندسو التصنيع في مايو كلينك على أعتاب تقديم علاجات حيوية جديدة

Mayo Clinic — Thu, 27 Mar 2025 00:05:35 EST

جاكسونفيل، ولاية فلوريدا -- يحتل مهندسو التصنيع الصدارة في جلب الأدوية الجديدة المشتقة من مصادر بشرية، مثل الخلايا والدم والجينات، للمرضى. وينتجون علاجات حيوية غالبًا ما تكون الأولى من نوعها لأمراض لم يكن لها في السابق سوى خيارات علاجية محدودة أو لم يكن لها أي خيارات.

FDA Approves Dual-Action Drug for Patients with Previously Treated Advanced Neuroendocrine Tumors, Backed by Dana-Farber Research

Dana-Farber Cancer Institute — Wed, 26 Mar 2025 10:15:08 EST

The FDA approval was based on results from the CABINET study, a phase 3 pivotal trial evaluating cabozantinib compared with placebo in two groups of patients with previously treated NETs: advanced pancreatic NETs and advanced extra-pancreatic NETs. The study was led by Jennifer Chan, MD, MPH, clinical director of the gastrointestinal cancer center and director of the program in carcinoid and neuroendocrine tumors at Dana-Farber Cancer Institute.

Weight-Loss Drug Use Has Risen Sharply Among Children and Adults With Type 1 Diabetes

Johns Hopkins Bloomberg School of Public Health — Wed, 26 Mar 2025 09:40:49 EST

Popular prescription weight-loss drugs called GLP-1 receptor agonists are now frequently used by type 1 diabetes patients, despite limited data on the drugs' safety and effectiveness in this patient population, according to a study led by researchers at the Johns Hopkins Bloomberg School of Public Health.

A Review of Latest Tools and Technologies in Pharmaceutical Research

Chinese Academy of Sciences — Wed, 26 Mar 2025 09:35:41 EST

This comprehensive review analyzes cutting-edge tools and technologies in modern pharmaceutical research, focusing on artificial intelligence, multi-omics technologies, and experimental methods. The study highlights how computational methods enhance drug discovery efficiency, while omics technologies provide systematic frameworks for investigating drug mechanisms. The integration of these advanced approaches has enabled more diverse and personalized treatment strategies, though challenges remain in drug development complexity, cost-effectiveness, and operational feasibility.

Preclinical Study: After Heart Attack, a Boost in Anti-Inflammatory Cells Promoted Healing

Cedars-Sinai — Wed, 26 Mar 2025 05:05:45 EST

A scientific technique that rapidly increases the body's production of anti-inflammatory cells promoted healing from heart attacks in mice, according to a new study by investigators from the Smidt Heart Institute at Cedars-Sinai.

Why Is it Important to Choose a Pediatric Research Hospital With Access to Clinical Trials?

Children's Hospital Los Angeles — Tue, 25 Mar 2025 20:15:16 EST

Every cancer treatment that exists for children was tested in a clinical trial.Clinical research and clinical trials are the only way to develop new and better therapies for children with cancer. Pediatric research studies and clinical trials find safe and effective therapies and improve ways of preventing and diagnosing childhood diseases.

ACC.25: Smidt Heart Institute Experts Present Late-Breaking Research

Cedars-Sinai — Tue, 25 Mar 2025 19:50:00 EST

Physicians and investigators from the Smidt Heart Institute at Cedars-Sinai will present research and be honored for their ongoing work in cardiovascular research and care during the American College of Cardiology's Annual Scientific Session taking place March 29-31 in Chicago.

Sylvester Cancer Tip Sheet - March 2025

Sylvester Comprehensive Cancer Center — Fri, 21 Mar 2025 19:35:03 EST

Rising leukemia rates in Florida linked to aging population, new treatment guidelines for follicular lymphoma, a new study that may help unlock immunotherapy for glioblastoma, and more are in this month's tip sheet from Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine.

New Drug Therapy Combination Shows Promise for Advanced Melanoma Patients

Huntsman Cancer Institute at the University of Utah — Fri, 21 Mar 2025 10:25:45 EST

A novel oral combination drug therapy evaluated at Huntsman Cancer Institute could treat and prevent melanoma spreading to the brain. Brain metastasis is the main cause of death from melanoma.

Registration for TCT 2025 Now Open

Cardiovascular Research Foundation (CRF) — Thu, 20 Mar 2025 19:35:14 EST

The Cardiovascular Research Foundation (CRF) is pleased to announce that registration is now open for TCT 2025 (Transcatheter Cardiovascular Therapeutics(r)), the world's premier educational symposium in interventional cardiovascular medicine. TCT 2025 will take place October 25-28, 2025, at the Moscone Center in San Francisco, California.

UTEP Researchers Test New, More Reliable Method to Detect Chagas Disease

University of Texas at El Paso — Thu, 20 Mar 2025 18:20:11 EST

Researchers at The University of Texas at El Paso have successfully tested a faster, more sensitive and reliable way to diagnose Chagas disease, a debilitating parasitic illness that affects approximately 6 million people worldwide. The results of the new study were recently published in the International Journal of Molecular Sciences.

Childhood Leukemia Isn't What It Used to Be: Latest Treatments, Research, and Reasons to Hope

Children's Hospital Los Angeles — Thu, 20 Mar 2025 17:50:50 EST

Hearing the word "leukemia" can be alarming in any context. Hearing it in the context of your child's health might feel terrifying, unfair, and even hopeless. But according to leading pediatric leukemia experts, families grappling with the news of a diagnosis have reason to feel .Today, for a great majority of pediatric leukemia cases, a new diagnosis doesn't mean what it meant 30, 20, or even 10 years ago.

Post-Transfusion Activation of Coagulation Pathways During Severe COVID-19 Correlates with COVID-19 Convalescent Plasma Antibody Profiles

Mount Sinai Health System — Wed, 19 Mar 2025 07:00:48 EST

Artificial Intelligence Tool Helps Predict Who Will Benefit From Focal Therapy for Prostate Cancer

University of California, Los Angeles (UCLA), Health Sciences — Tue, 18 Mar 2025 10:35:43 EST

A study led by UCLA investigators shows that artificial intelligence (AI) could play a key role in improving treatment outcomes for men with prostate cancer by helping physicians determine who is most likely to benefit from partial gland cryoablation, a minimally invasive procedure that treats localized prostate tumors.

Roswell Park Named One of Only 37 Optum Cancer Centers of Excellence for Adult and Pediatric Patients

Roswell Park Comprehensive Cancer Center — Mon, 17 Mar 2025 18:50:30 EST

Roswell Park Named One of Only 37 Optum Cancer Centers of Excellence for Adult and Pediatric Patients