News Curated �鶹��ý Channel: National Institutes of Health (NIH)

Powerful New Software Platform Could Reshape Biomedical Research by Making Data Analysis More Accessible

Mount Sinai Health System — Thu, 03 Apr 2025 14:00:00 EST

A powerful new software platform called the Playbook Workflow Builder is set to transform biomedical research by allowing scientists to conduct complex and customized data analyses without advanced programming skills. An article that describes the new platform was published in the April 3 online issue of the journal PLOS Computational Biology. Developed by a multi-institutional team that was led by Icahn School of Medicine at Mount Sinai investigators as part of the National Institutes of Health Common Fund Data Ecosystem (CFDE) program, researchers from across the United States developed the web-based platform that enables scientists to analyze and visualize their own data independently through an intuitive, interactive interface.

Laughing Gas: An Old Drug's New Trick to Fight Depression

Perelman School of Medicine at the University of Pennsylvania — Thu, 03 Apr 2025 10:25:22 EST

Nitrous oxide--better known as "laughing gas"--can potentially transform treatment for tough-to-beat depression. This centuries-old anesthetic gas targeted specific brain cells in mice and quickly reduced symptoms, according to new research from the Perelman School of Medicine at the University of Pennsylvania, reported today in Nature Communications.

Under Embargo: Landmark Research Recommends Gastric Bypass for People with Severe Obesity Undergoing Surgery

University of Bristol — Mon, 31 Mar 2025 10:50:33 EST

Gastric bypass is the most clinically and cost effective form of interventional surgery for people living with severe obesity, reveals landmark research. The new University of Bristol-led trial, funded by the National Institute for Health and Care Research (NIHR), is published today [31 March] in the Lancet Diabetes & Endocrinology journal.

Mayo Clinic Researchers Study Causes of Rapidly Progressive Dementia

Mayo Clinic — Mon, 31 Mar 2025 08:00:58 EST

Most patients with Alzheimer's disease and Alzheimer's Disease Related Dementias (ADRD) experience the gradual onset and progression of cognitive symptoms, leading to decline over years or decades. However, in a small subset of patients, symptoms begin rapidly, leading to dementia within one year and complete incapacitation within two years of symptom onset.

AACI Statement on Continued Reductions in Force

Association of American Cancer Institutes (AACI) — Fri, 28 Mar 2025 20:05:56 EST

The Association of American Cancer Institutes (AACI) remains strongly opposed to the indiscriminate firing of dedicated public servants across the federal government.

Meniscus Injuries May Soon Be Treated by Customizable Hydrogel

Perelman School of Medicine at the University of Pennsylvania — Fri, 28 Mar 2025 19:00:59 EST

A new 3D printed customizable hydrogel performed well in preclinical trials with several different types of meniscal tears

Endocrine Society Statement on HHS Restructuring, Mass Firings, and Scientific Review

Endocrine Society — Fri, 28 Mar 2025 18:15:20 EST

A major reorganization of the U.S. Department of Health and Human Services (HHS)--including massive cuts to the federal workforce--threatens scientific progress that drives our economy and improves the public's health.

AAHRPP Accredits Two More International Organizations, Including the First in United Arab Emirates

Association for the Accreditation of Human Research Protection Programs — Thu, 27 Mar 2025 19:40:38 EST

AAHRPP Accredits Two More International Organizations, Including the First in United Arab Emirates

ASBMB Honors Lawrence Tabak with Public Service Award

American Society for Biochemistry and Molecular Biology (ASBMB) — Wed, 26 Mar 2025 20:50:40 EST

He will deliver prerecorded remarks at the 2025 ASBMB Annual Meeting in Chicago.

Highly Educated People Face Steeper Mental Declines After Stroke

Michigan Medicine - University of Michigan — Wed, 26 Mar 2025 11:00:00 EST

Stroke survivors who have attended some level of higher education may face even steeper mental declines, according to a study led by Michigan Medicine. The findings suggest that attending higher education may enable people to retain greater cognitive ability until a critical threshold of brain injury is reached after a stroke.

Scientists Demonstrate Pre-clinical Proof of Concept for Next-Gen DNA Delivery Technology

Wistar Institute — Fri, 21 Mar 2025 11:05:00 EST

Wistar Institute scientists and collaborators describe a next-generation vaccination technology that combines plasmid DNA with a lipid nanoparticle delivery system.

NIH Researchers Develop Eye Drops That Slow Vision Loss in Animals

NIH, National Eye Institute (NEI) — Fri, 21 Mar 2025 10:15:34 EST

Researchers at the National Institutes of Health (NIH) have developed eye drops that extend vision in animal models of a group of inherited diseases that lead to progressive vision loss in humans, known as retinitis pigmentosa.

New Rules for the Game of Memory

University of Chicago Medical Center — Thu, 20 Mar 2025 18:00:27 EST

New research from UChicago upends traditional views on how synaptic plasticity supports memory and learning.

Endocrine Society Calls for Restoration of Diabetes Prevention Program

Endocrine Society — Thu, 20 Mar 2025 05:10:08 EST

Three decades of landmark research into type 2 diabetes prevention abruptly ended this month due to government funding cuts.

Study Confirms Safety and Efficacy of Higher-Dose-Per-Day Radiation for Early-Stage Prostate Cancer

University of California, Los Angeles (UCLA), Health Sciences — Tue, 18 Mar 2025 18:40:09 EST

A new large-scale study provides the strongest evidence yet that a shorter, standard-dose course radiation treatment is just as effective as conventional radiotherapy for prostate cancer, without compromising the safety of patients.

Anti-obesity medication boosts weight loss when behavioral therapy falls short

Perelman School of Medicine at the University of Pennsylvania — Tue, 18 Mar 2025 17:40:49 EST

Adding an anti-obesity medication just one month after behavioral therapy begins--rather than waiting the currently recommended six months--can more than double weight loss for patients who struggle initially with lifestyle changes alone, according to new research published in Nature Medicine from a team at the Perelman School of Medicine at the University of Pennsylvania.

Protein Plays Dual Role in Causing, Preventing Sepsis

UT Southwestern Medical Center — Mon, 17 Mar 2025 11:15:52 EST

A protein called angiopoietin-2 (ANGPT2) can both inhibit and encourage blood vessel changes critical for sepsis, a leading cause of hospital deaths worldwide, a new study led by UT Southwestern Medical Center researchers shows.

Drug Building Blocks Pave Path to New Sepsis Treatments

Sanford Burnham Prebys — Tue, 11 Mar 2025 20:25:14 EST

The immune system typically can ramp up the body's defenses to clear out an invading threat without issue. Glitches can happen, however, with sepsis occurring when the mustered army of cells also attacks the body's own tissues and organs as if they were enemy combatants.

Studying Chemical Exposure and Brain Cancer Risk in Firefighters

Yale Cancer Center/Smilow Cancer Hospital — Mon, 10 Mar 2025 08:40:45 EST

The study co-led by Dr. Elizabeth Claus of Yale Cancer Center showed an increased presence of haloalkane-associated mutational signatures in the firefighters' tumors.

Early-Life Gut Microbes May Protect Against Diabetes, Research in Mice Suggests

University of Utah Health — Thu, 06 Mar 2025 14:00:00 EST

Gut microbes shape pancreas development in infancy, leading to long-term changes in diabetes risk, new research in mice has found. The results could ultimately help doctors reduce the risk of type 1 diabetes--or potentially even restore lost pancreatic function in adulthood--with microbes that help the pancreas heal.