News Curated �鶹��ý Channel: National Institutes of Health (NIH)

Discovery Illuminates How Sleeping Sickness Parasite Outsmarts Immune Response

Johns Hopkins Bloomberg School of Public Health — Wed, 30 Oct 2024 12:15:00 EST

A new study led by researchers at the Johns Hopkins Bloomberg School of Public Health sheds light on how the blood-borne parasite that causes African sleeping sickness in humans and related diseases in cattle and other animals establishes long-term infections in hosts. Using a mouse model, the researchers showed thatTrypanosoma brucei essentially plays a game of hide-and-seek by setting up shop in its hosts' tissues, allowing it to constantly change its protective surface coat and evade antibodies.

Wayne State Researcher Secures Two Grants From the National Institute on Aging to Address Alzheimer's Disease

Wayne State University Division of Research — Fri, 25 Oct 2024 14:30:57 EST

A Wayne State University School of Medicine faculty member has been awarded a total of $2.3 million by the National Institute on Aging of the National institutes of Health for two new, concurrent projects that both address questions related to Alzheimer's disease, a progressive, age-related degenerative brain disease characterized by memory problems, impaired judgment, cognitive issues and changes in personality.

A Wealth of Funding Resources: CHLA's Research Success Teams Program Supports Junior Investigators Seeking NIH Grants

Children's Hospital Los Angeles — Thu, 24 Oct 2024 11:50:42 EST

As an early career researcher, it's understandable to view the process of securing funding from the National Institutes of Health (NIH) as daunting. That's exactly why the Research Success Teams (RST) program at Children's Hospital Los Angeles was created.

UCLA Researchers Engineer Experimental Drug for Preventing Heart Failure After Heart Attacks

University of California, Los Angeles (UCLA), Health Sciences — Thu, 24 Oct 2024 11:00:00 EST

An experimental therapeutic monoclonal antibody therapy could become the first to directly enhance tissue repair in the heart following a heart attack.

Can Small Bursts of Activity Throughout the Day Decrease Chronic Pain?

Wake Forest University School of Medicine — Wed, 23 Oct 2024 16:10:52 EST

Setting out to prove that movement indeed is medicine for older adults with chronic knee and hip pain, Wake Forest University researchers have received a $5.7 grant from the National Institutes of Health (NIH) to conduct a five-year study.

Live Well, Think Well: Research Shows Healthy Habits Tied to Brain Health

American Academy of Neurology (AAN) — Wed, 23 Oct 2024 16:00:00 EST

In middle-aged people, having risk factors like blood pressure, blood sugar and cholesterol that are not well-controlled combined with not following certain healthy habits including exercise, diet and sleep, are linked to a higher risk of stroke, dementia or depression later in life, according to a study published in the October 23, 2024, online issue of Neurology(r), the medical journal of the American Academy of Neurology.

Six Yale Researchers Receive NIH 'High-Risk, High-Reward' Awards

Yale School of Medicine — Mon, 21 Oct 2024 16:30:57 EST

The National Institutes of Health (NIH) have awarded grants to six Yale researchers who are conducting exceptional and creative research with the potential to transform biomedical science.

A 37% Drop in Overdose Deaths From Drugs Mixed with Opioids - Fentanyl Included

Ohio State University — Mon, 21 Oct 2024 11:55:26 EST

Expanded treatment options, increased naloxone distribution and targeted education campaigns likely led to a 37% reduction in overdose deaths from opioids combined with stimulant drugs other than cocaine, according to the results of a large federally funded study.

FSU College of Medicine Research Team Connects Loneliness with Heightened Risk of Dementia in Largest Study of Its Kind

Florida State University — Mon, 21 Oct 2024 11:25:55 EST

New research led by Florida State University College of Medicine faculty quantified the association between loneliness and dementia by analyzing data from more than 600,000 people around the world -- the largest study of its kind. The meta-analysis of 21 longitudinal studies showed that experiencing feelings of loneliness increased the risk of developing dementia by 31%.

An Ultrasound-Activated Hydrogel for Steady, Sustained Drug Delivery

Michigan Medicine - University of Michigan — Fri, 18 Oct 2024 15:00:01 EST

Researchers at Michigan Medicine have developed a composite hydrogel capable of achieving sustained, steady drug release using ultrasound as a trigger.

Study Shows That Rett Syndrome in Females Is Not Just Less Severe, but Different

UC Davis Health — Thu, 17 Oct 2024 18:55:54 EST

Symptoms progression of Rett syndrome are different in females than males. A new MIND Institute study shows why it is important to understand these differences to develop better treatments.

Study Seeks Rapid, Paper-Based Test to Detect Cancer Cells in Cerebrospinal Fluid

University of California, Los Angeles (UCLA), Health Sciences — Thu, 17 Oct 2024 16:10:18 EST

With time being of the essence for patients facing one of cancer's most dire complications, UCLA researchers are working to create a new test to detect cancer's spread to the central nervous system on the same day as the doctor's visit.

NIH Study Explores Pollution Exposure and Birth Outcomes in Pregnant Women Living in Historically Redlined Neighborhoods

Environmental influences on Child Health Outcomes NIH — Thu, 17 Oct 2024 14:10:46 EST

Teal Health is Awarded a $1.68 Million SBIR Grant from the National Cancer Institute (NCI) of the National Institutes of Health (NIH) for At-Home Cervical Cancer Screening

Teal Health — Thu, 17 Oct 2024 09:25:51 EST

Teal Health, a woman-led company on a mission to get all women and people with a cervix in the US screened for cervical cancer, has been awarded a $1.68 million Small Business Innovation Research (SBIR) Direct to Phase II Grant from the National Cancer Institute (NCI) of the National Institutes of Health (NIH).

Breakthrough Clinical Trial Reveals Better Treatment for Advanced Classic Hodgkin Lymphoma

Roswell Park Comprehensive Cancer Center — Wed, 16 Oct 2024 20:45:30 EST

Updated results from a phase 3 clinical trial are expected to change the way advanced stage classic Hodgkin lymphoma (cHL) is treated. Details appear in a study published today in The New England Journal of Medicine. Drs. Kara Kelly of Roswell Park Comprehensive Cancer Center and Sharon Castellino of Children's Healthcare of Atlanta and Emory University School of Medicine/Winship Cancer Institute of Emory University served as pediatric leads of this important trial in children and adults with lymphoma.

3 From WashU Receive Prestigious NIH Director's Awards

Washington University in St. Louis — Wed, 09 Oct 2024 10:05:56 EST

Three researchers from Washington University in St. Louis have received highly competitive and prestigious NIH Director's awards, totaling $10 million in "High Risk, High Reward" medical research funding to be used over the next five years.

History of COVID-19 Doubles Long-term Risk of Heart Attack, Stroke and Death

Cleveland Clinic — Wed, 09 Oct 2024 05:00:00 EST

Cleveland: A history of COVID-19 can double the risk of heart attack, stroke or death according to new research led by Cleveland Clinic and the University of Southern California. The study found that people with any type of COVID-19 infection were twice as likely to have a major cardiac event, such as heart attack, stroke or even death, for up to three years after diagnosis.

Scientists at The Wistar Institute Discover Novel Series of SARS-CoV-2 Mpro Inhibitors for Potential New COVID-19 Treatments

Wistar Institute — Tue, 08 Oct 2024 09:05:52 EST

New research from the Salvino lab identifies novel series of MPro inhibitors

Study Shows Cancer Vaccine Blocks Tumor Progression at Early Lesion Stage

Vanderbilt University Medical Center — Mon, 07 Oct 2024 15:05:16 EST

A cancer vaccine that had little success in clinical trials for patients with advanced tumors could potentially have efficacy if administered earlier in the treatment cycle, according to a study from Vanderbilt researchers.

New Addition to Standard-of-Care Treatments for Non-Small-Cell Lung Cancer Patients Has Potential to Increase Progression-Free Survival

Houston Methodist — Thu, 03 Oct 2024 19:05:15 EST

Houston Methodist researchers have developed an advanced mathematical model that predicts how novel treatment combinations could significantly extend progression-free survival for patients with non-small-cell lung cancer (NSCLC), the most common type of lung cancer.