News Curated �鶹��ý Channel: National Eye Institute (NEI)

NIH-Led Studies Point to Potential Development of a Cataract Drug

NIH, National Eye Institute (NEI) — Wed, 18 Sep 2024 11:05:00 EST

Researchers at the National Institutes of Health (NIH) and their collaborators have identified a protein, known as RNF114, that reverses cataracts, a clouding of the eye's lens that occurs commonly in people as they age.

Two Common Surgeries Equally Effective for Treating Blinding Condition of the Eyelid

NIH, National Eye Institute (NEI) — Tue, 17 Sep 2024 14:00:00 EST

Trachomatous trichiasis, a potentially blinding condition where inward-turned eyelashes scratch the front of the eye, can successfully be treated by either of the two most common types of eyelid surgery, according to findings from a large comparison trial funded by the National Institutes of Health.

The latest mpox outbreak and its threat to vision

NIH, National Eye Institute (NEI) — Tue, 27 Aug 2024 15:30:53 EST

Monkeypox virus (mpoxv) has re-emerged, designated on August 14 as a global emergency by the World Health Organization. Newly evolved strains of mpox viruses can efficiently spread among people. In addition to skin rashes, mpox infection can cause eye complications including inflammation of the clear tissue covering the iris and pupil called the cornea (keratitis), the tissue covering the white of the eye and the underside of the eyelid (conjunctivitis, or pink eye), and the eyelid (blepharitis).

NIH researchers discover potential therapeutic target for degenerative eye disease

NIH, National Eye Institute (NEI) — Fri, 26 Jul 2024 17:05:48 EST

Supplements slow disease progression during late stage of "dry" age-related macular degeneration

NIH, National Eye Institute (NEI) — Tue, 16 Jul 2024 12:05:24 EST

In a new analysis of data, researchers at the National Institutes of Health (NIH) have found that taking a daily supplement containing antioxidant vitamins and minerals slows progression of late-stage dry age-related macular degeneration (AMD), potentially helping people with late-stage disease preserve their central vision.

NIH researchers discover a new face-detecting brain circuit

NIH, National Eye Institute (NEI) — Tue, 02 Jul 2024 11:00:00 EST

Scientists at the National Institutes of Health (NIH) have uncovered a brain circuit in primates that rapidly detects faces. The findings help not only explain how primates sense and recognize faces, but could also have implications for understanding conditions such as autism, where face detection and recognition are often impaired from early childhood.

Discovery in hibernating animals could extend the shelf life of cells and tissues for transplantation

NIH, National Eye Institute (NEI) — Tue, 11 Jun 2024 12:05:40 EST

Research led by scientists at the National Eye Institute and Sun Yat-sen University, Guangzhou, China points to a potential strategy for extending the cold storage shelf life of donor cells and tissues, such as those of the pancreas, an organ crucial for making insulin.

Babies Attend to Clues of Meaning as They Take in Complex Visual World

NIH, National Eye Institute (NEI) — Wed, 27 Mar 2024 11:05:37 EST

Findings from a National Eye Institute-supported study show for the first time that when babies look at photos of unfamiliar everyday scenes, such as an office or a lab, they tend to fixate on the same regions where adults find meaning. This inclination to home in on what's interesting or meaningful grows more pronounced as babies age. The findings, published in Infancy, provide a more nuanced understanding of visual development, which may lead to earlier detection of brain-based causes of vision problems, such as cerebral/cortical visual impairment.

NEI Study Points to 'Ground Zero' for AMD Development

NIH, National Eye Institute (NEI) — Wed, 27 Mar 2024 10:05:18 EST

National Eye Institute researchers studying human retinas discovered 87 target genes where a mix of environmental factors likely influence one's risk of developing age-related macular degeneration (AMD), a leading cause of vision loss in people ages 65 and older.

Inflammation-Reducing Drug Shows No Benefit for Dry Age-Related Macular Degeneration in Nih Trial

NIH, National Eye Institute (NEI) — Thu, 21 Mar 2024 11:30:33 EST

The drug minocycline, an antibiotic that also decreases inflammation, failed to slow vision loss or expansion of geographic atrophy in people with dry age-related macular degeneration (AMD), according to a phase II clinical study at the National Eye Institute (NEI), part of the National Institutes of Health.

Inflammation-reducing drug shows no benefit for dry age-related macular degeneration in NIH trial

NIH, National Eye Institute (NEI) — Thu, 21 Mar 2024 11:05:08 EST

New technique enhances quality control of lab-grown cells for AMD treatment

NIH, National Eye Institute (NEI) — Thu, 18 Jan 2024 15:05:51 EST

Researchers at the National Eye Institute (NEI) have improved a crucial step in the production of retinal pigment epithelium (RPE), a tissue they grow in the lab from patient blood cells and are testing in a clinical trial as treatment for age-related macular degeneration (AMD).

Metabolomics: A New Approach to Understanding Glaucoma

NIH, National Eye Institute (NEI) — Tue, 14 Nov 2023 18:05:10 EST

Glaucoma remains one of the most common causes of vision loss and blindness in the U.S. and much of the world, disproportionately affecting older people, African Americans, and Hispanics and Latinos.

Scientists discover external protein network can help stabilize neural connections

NIH, National Eye Institute (NEI) — Wed, 16 Aug 2023 11:00:00 EST

The Noelin family of secreted proteins bind to the external portion of AMPA glutamate receptors and stabilize them on the neuronal cellular membrane, a process necessary for transmission of full-strength signals between neurons, according to a study in mice from the National Eye Institute (NEI) and the University of Freiberg, Germany.

Gene that regulates immune activity in the retina identified

UT Southwestern Medical Center — Tue, 11 Jul 2023 11:25:56 EST

UT Southwestern Medical Center researchers have identified a gene called Lipe that appears to be pivotal to retinal health, with mutations spurring immune activation and retinal degeneration. This is important because the retina is responsible for detecting the light that is transformed into vision. The findings, published in Communications Biology, provide clues about the mechanisms behind a variety of disorders affecting the retina, including macular degeneration and diabetic retinopathy.

Intraocular corticosteroids best for treating complications of chronic inflammatory eye condition

NIH, National Eye Institute (NEI) — Tue, 13 Jun 2023 09:00:00 EST

Repeat treatment with corticosteroid injections improved vision in people with persistent or recurrent uveitis-related macular edema better than two other therapies, according to results from a clinical trial funded by the National Eye Institute (NEI).

AI Used to Advance Drug Delivery System for Glaucoma and Other Chronic Diseases

Johns Hopkins Medicine — Wed, 24 May 2023 09:00:41 EST

Wilmer Eye Institute, Johns Hopkins Medicine researchers say they have used artificial intelligence models and machine-learning algorithms to successfully predict which components of amino acids that make up therapeutic proteins are most likely to safely deliver therapeutic drugs to animal eye cells.

Study: Blood Vessel Damage Could Be an Alzheimer's Driver

Cedars-Sinai — Fri, 19 May 2023 20:05:47 EST

Blood vessel abnormalities in the eye are a major factor in the progression of Alzheimer's disease, according to research from Cedars-Sinai investigators published in the peer-reviewed journal Alzheimer's & Dementia: The Journal of the Alzheimer's Association.

NEI Scientists publish recipe for making blood vessel cells from patient stem cells

NIH, National Eye Institute (NEI) — Tue, 16 May 2023 09:30:59 EST

Researchers at NIH's National Eye Institute have published a detailed protocol for making three cell types that are key components to form blood vessels and capillaries.

Scientists discover anatomical changes in the brains of the newly sighted

Massachusetts Institute of Technology (MIT) — Mon, 01 May 2023 18:05:38 EST

In a new study, Sinha and his colleagues have now discovered anatomical changes that occur in the brains of these patients after their sight is restored. These changes, seen in the structure and organization of the brain's white matter, appear to underlie some of the visual improvements that the researchers also observed in these patients.