News Curated �鶹��ý Channel: National Institute on Aging (NIA)

Ulcers and Damage to Upper Gastrointestinal Tract Linked to Increased Risk of Parkinson's Disease, Research Demonstrates

Beth Israel Lahey Health — Fri, 06 Sep 2024 11:05:10 EST

A study led by researchers at Beth Israel Deaconess Medical Center (BIDMC) found the risk of developing Parkinson's disease was 76 percent higher among those with a history of damage to the lining of their upper gastrointestinal (GI) tract than among those without.

Estrogen cream does not improve success rate for prolapse repair

UT Southwestern Medical Center — Tue, 15 Aug 2023 12:20:51 EST

Vaginal estrogen cream, which is commonly prescribed to help women after surgery for pelvic organ prolapse (POP), did not prevent a recurrence of the condition, according to results of a multicenter clinical trial led by UT Southwestern Medical Center. However, the medication did reduce symptoms of vaginal atrophy. The findings, reported in JAMA, could lead to new ways to improve outcomes of prolapse repairs, the study authors said.

Can AI help hospitals spot patients in need of extra non-medical assistance?

Michigan Medicine - University of Michigan — Mon, 14 Aug 2023 12:15:06 EST

Needs related to housing, transportation, food, social support and more can be identified through AI/ML techniques.

Experts: Chronic pain patients who take opioids need better care & coverage

Michigan Medicine - University of Michigan — Mon, 14 Aug 2023 11:45:36 EST

People with chronic pain who take opioids have trouble finding multimodal pain care; insurance and provider education changes are needed, experts say.

UC Irvine is part of $16 million effort to increase dementia research representation

University of California, Irvine — Wed, 02 Aug 2023 11:45:00 EST

With a $16 million grant from the National Institute on Aging, the University of California, San Francisco and the University of California, Irvine will work with community partners to improve the representation of Asian American, Native Hawaiian and Pacific Islander adults in research on aging, caregiving, and Alzheimer's disease and related dementias.

Transcription Factors Contribute to Subtypes of Colorectal Cancers

Johns Hopkins Medicine — Thu, 27 Jul 2023 11:05:15 EST

New research in colorectal cancers directed by investigators at the Johns Hopkins Kimmel Cancer Center suggests that expression of transcription factors -- proteins that help turn specific genes on or off by binding to nearby DNA -- may play a central role in the degree of DNA methylation across the genome, contributing to the development of different subtypes of these cancers. Methylation is a process in which certain chemical groups attach to areas of DNA that guide genes' on/off switches.

People with Increased Genetic Risk of Alzheimer's May Lose Sense of Smell First

American Academy of Neurology (AAN) — Wed, 26 Jul 2023 16:00:00 EST

People who carry the gene variant associated with the strongest risk for Alzheimer's disease may lose their ability to detect odors earlier than people who do not carry the gene variant, which may be an early sign of future memory and thinking problems, according to a study published in the July 26, 2023, online issue of Neurology(r), the medical journal of the American Academy of Neurology. The gene variant associated with this increased risk of Alzheimer's is called APOE e4.

Dementia becomes an emergency 1.4 million times a year

Michigan Medicine - University of Michigan — Mon, 24 Jul 2023 11:00:00 EST

More than 1.4 million times a year, people with Alzheimer's disease and other forms of dementia end up in emergency care, making up nearly 7% of all emergency visits for any reason by people over age 65, a new study shows. Compared with their peers who don't have dementia, these patients have twice the rate of seeking emergency care after an accident or a behavioral or mental health crisis.

New study shows anti-inflammatory drugs as a promising target for Alzheimer's disease

University of Kentucky — Mon, 17 Jul 2023 09:55:39 EST

A recent study from the lab of the University of Kentucky's Sanders-Brown Center on Aging Director Linda Van Eldik, Ph.D., has been published in PLOS ONE. The work centers around the idea that various anti-inflammatory drugs could be effective treatments for Alzheimer's disease (AD). This study focused on a protein known as p38.

Second Year of COVID Pandemic Brought Spike in Child Mental Health Visits to ED

Harvard Medical School — Wed, 12 Jul 2023 11:00:00 EST

The number of young people in the United States visiting hospital emergency departments for mental health crises increased sharply during the second year of the COVID-19 pandemic, according to a study led by researchers from the Department of Health Care Policy in the Blavatnik Institute at Harvard Medical School.

Drug studied at UK is 1st disease-modifying therapy in U.S. approved to treat Alzheimer's

University of Kentucky — Wed, 12 Jul 2023 10:10:26 EST

On July 6, 2023, the U.S. Food and Drug Administration (FDA) granted full approval to lecanemab, marketed as Leqembi, for the treatment of Alzheimer's disease. The University of Kentucky's Sanders-Brown Center on Aging has been working with this drug and others like it for more than a decade.

Penn Medicine Researchers to Lead $40 Million, Multisite Study of Alzheimer's Disease in Asian Americans and Asian Canadians

Perelman School of Medicine at the University of Pennsylvania — Tue, 11 Jul 2023 10:00:00 EST

A $40.5 million grant from the National Institute on Aging (NIA), part of the National Institutes of Health (NIH), will fund the Asian Cohort for Alzheimer's Disease (ACAD) study at Penn Medicine and 15 other academic research centers across the United States and Canada.

Expanding Medicaid improved care without crowding out other patients

Michigan Medicine - University of Michigan — Fri, 07 Jul 2023 11:05:11 EST

People with low incomes who live in states that expanded Medicaid got more of the kind of health care that can keep them healthier in the long run, compared with similar people in non-expansion states.

Robotic Glove that 'Feels' Lends a 'Hand' to Relearn Playing Piano After a Stroke

Florida Atlantic University — Thu, 29 Jun 2023 00:00:00 EST

A soft robotic glove is lending a "hand" and providing hope to piano players who have suffered a disabling stroke. Combining flexible tactile sensors, soft actuators and AI, this robotic glove is the first to "feel" the difference between correct and incorrect versions of the same song and to combine these features into a single hand exoskeleton. Unlike prior exoskeletons, this new technology provides precise force and guidance in recovering the fine finger movements required for piano playing and other complex tasks.

Poor Sense of Smell Linked to Increased Risk of Depression in Older Adults

Johns Hopkins Medicine — Mon, 26 Jun 2023 10:00:50 EST

In a study that followed more than 2,000 community-dwelling older adults over eight years, researchers at Johns Hopkins Medicine say they have significant new evidence of a link between decreased sense of smell and risk of developing late-life depression.

Is TBI a Chronic Condition?

American Academy of Neurology (AAN) — Wed, 21 Jun 2023 16:00:00 EST

People with TBI may continue to improve or decline years after their injury, making it a more chronic illness, according to a study published in the June 21, 2023, online issue of Neurology(r), the medical journal of the American Academy of Neurology.

UC Irvine to lead multi-institutional study of single-cell vulnerabilities to Alzheimer's disease

University of California, Irvine — Thu, 15 Jun 2023 16:35:57 EST

The University of California, Irvine has received a five-year, $10 million grant from the National Institutes of Health to lead a multi-institutional study of specific brain cell vulnerabilities to abnormal tau protein deposits in regions affected in the early stages of Alzheimer's disease.

Nursing home dementia residents' care linked to majority presence, UC Irvine-led study finds

University of California, Irvine — Tue, 06 Jun 2023 12:55:46 EST

The quality of care for nursing home residents with Alzheimer's disease and related dementias is best when they are in the majority, but most facilities also accommodate a heterogeneous population, where specialized staff training is limited, according to a study led by the University of California, Irvine.

Treating Asymptomatic Elevated Blood Pressure Linked to Cardiac and Kidney Injury

Beth Israel Deaconess Medical Center — Thu, 01 Jun 2023 11:05:39 EST

Researchers found that receiving intensive antihypertensive treatment as an inpatient was linked with greater risk of adverse events, particularly for patients receiving the medication intravenously as opposed to orally.

UCLA-led research suggests no difference in health outcomes, care costs for patients treated by traditional MDs or osteopaths

University of California, Los Angeles (UCLA), Health Sciences — Mon, 29 May 2023 17:00:00 EST

New UCLA-led research suggests that patient mortality rates, readmissions, length of stay, and health care spending were virtually identical for elderly hospitalized patients who were treated by physicians with Doctor of Medicine (MD) or Doctor of Osteopathic Medicine (DO) degrees.