News Curated �鶹��ý Channel: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Increased Cancer Risk for Kidney Transplant Recipients Linked to Epstein-Barr Virus

Perelman School of Medicine at the University of Pennsylvania — Mon, 10 Feb 2025 10:00:04 EST

More than 90% of the adult population in the U.S. is or has been infected with Epstein Barr virus (EBV). EBV is a highly contagious member of the herpes virus family, best known for causing infectious mononucleosis ("mono") and for its association with several cancers and autoimmune diseases. Kidney transplant patients who've never been exposed to EBV but receive organs from a donor who carried the virus may develop a life-threatening post-transplant complication called lymphoproliferative disorder (PTLD), according to a new study from the Perelman School of Medicine at the University of Pennsylvania. An estimated 4 to 5 percent of adult kidney transplants - as many as 1200 patients per year - could be at risk of the condition, in which the body's immune system gets confused and immune cells can grow out of control and act like cancer. The findings were recently published in Annals of Internal Medicine.

Research in Fruit Flies Pinpoints Brain Pathways Involved in Alcohol-Induced Insomnia

University of Utah Health — Thu, 06 Feb 2025 11:00:00 EST

The study identified specific neurotransmitters and brain cells that are involved in alcohol-induced insomnia. This work could ultimately lead to targeted treatments for alcohol-related sleep loss, helping people recover from alcohol use disorder.

UC Irvine Public Health Researchers Uncover Improved Trends and Patterns in Anti-Diabetic Medication

University of California, Irvine — Fri, 10 Jan 2025 19:30:13 EST

Improved patterns of anti-diabetic medication use and declining rates of various life-threatening acute diabetes complications are closing the disparities gap for American Indian and Alaska Native populations with Type 2 diabetes.

Pushing Kidney-Stone Fragments Reduces Stones' Recurrence

University of Washington School of Medicine and UW Medicine — Thu, 19 Sep 2024 14:05:53 EST

UW Medicine researchers found that patients who underwent the stone-moving ultrasound procedure had a 70% lower risk of such a recurrence. The Journal of Urology published the findings in August.

One of the First of Its Kind, Uah Study Characterizes Urinary Microbes in Children

University of Alabama Huntsville — Fri, 06 Sep 2024 15:05:44 EST

Until recently, it was believed that human urine is sterile, but advanced culturing techniques and DNA sequencing have revealed that bacteria and other microbes - such as viruses and fungi - inhabit the human bladder and urinary tract, known collectively as the "urobiome." Now in study that is one of the first of its kind, Dr.

FAMU-FSU College of Engineering research shows how insulin, zinc and pH can block harmful protein clumps linked to Type 2 diabetes

Florida State University — Thu, 22 Aug 2024 11:05:50 EST

New research led by Ayyalusamy Ramamoorthy, a professor at the FAMU-FSU College of Engineering and the Florida State University-headquartered National High Magnetic Field Laboratory, shows how zinc, pH levels and insulin work together to inhibit the buildup of protein clumps that contribute to Type 2 diabetes.

Long-Term Study Reaffirms Benefits of Covid-19 Vaccination for Organ Transplant Recipients

Johns Hopkins Medicine — Fri, 18 Aug 2023 12:05:42 EST

A two-year study found that spikes of post-vaccination SARS-CoV-2 viral infections (commonly known as COVID-19 breakthrough cases) remain common, yet hospitalization rates have dramatically dropped following the first wave of the virus' omicron subvariant.

Diabetes linked to functional and structural brain changes through MRI

Michigan Medicine - University of Michigan — Thu, 10 Aug 2023 06:30:48 EST

A new study finds that the longer a person has type 2 diabetes, the more likely they may be to experience changes in brain structure. MRI results, researchers say, indicate the negative effects longstanding diabetes may have on brain health outcomes and emphasize the importance of preventing early onset type 2 diabetes.

VUMC receives $28 million to lead national study of COVID-diabetes link

Vanderbilt University Medical Center — Wed, 02 Aug 2023 13:55:23 EST

Researchers at Vanderbilt University Medical Center have received a four-year, $28 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases, part of the National Institutes of Health, to study the relationship between COVID-19 and diabetes.

Study provides new insights into Type 2 diabetes

Texas A&M AgriLife — Thu, 27 Jul 2023 13:20:54 EST

New insights into the underlying mechanisms of Type 2 diabetes and novel potential therapeutic targets for the disease were revealed in a recent study.

Storing fat at the waist may NOT up diabetes risk, surprise findings indicate

University of Virginia Health System — Thu, 27 Jul 2023 10:45:57 EST

Conventional wisdom holds that storing fat around your belly puts you at increased risk for type 2 diabetes. But surprising new findings from the University of Virginia School of Medicine suggest that naturally occurring variations in our genes can lead some people to store fat at the waist but also protect them from diabetes.

People with Increased Genetic Risk of Alzheimer's May Lose Sense of Smell First

American Academy of Neurology (AAN) — Wed, 26 Jul 2023 16:00:00 EST

People who carry the gene variant associated with the strongest risk for Alzheimer's disease may lose their ability to detect odors earlier than people who do not carry the gene variant, which may be an early sign of future memory and thinking problems, according to a study published in the July 26, 2023, online issue of Neurology(r), the medical journal of the American Academy of Neurology. The gene variant associated with this increased risk of Alzheimer's is called APOE e4.

Neurons that track, regulate blood-sugar levels are found

University of Washington School of Medicine — Tue, 11 Jul 2023 13:45:37 EST

Understanding how this blood-sugar detection system works and how these neurocircuits operate would give researchers and doctors greater insights into how our brains regulate our blood sugar and, perhaps, how to target them therapeutically to treat metabolic diseases like diabetes and obesity, according to the study authors.

Study Identifies Biomarker for Allergic Reaction in Kidneys

Johns Hopkins Medicine — Wed, 05 Jul 2023 10:00:56 EST

In a study led by Johns Hopkins Medicine, in collaboration with Yale School of Medicine, researchers have identified a biomarker found via a simple urine test that can be used to diagnose acute tubulointerstitial nephritis (AIN), a medical condition that causes inflammation of the kidneys and can lead to acute kidney injury (AKI) -- a sudden loss of kidney function. Experts say a kidney biopsy is often required to diagnose AIN because there are no disease-specific signs or symptoms.

Proteins Predict Significant Step Toward Development of Diabetes

Pacific Northwest National Laboratory — Thu, 29 Jun 2023 11:00:00 EST

Scientists have taken an important step forward in predicting who will develop Type 1 diabetes months before symptoms appear.

Study: Potential New Treatment Identified for Liver Disease

UC San Diego Health — Mon, 26 Jun 2023 14:05:31 EST

Researchers with UC San Diego School of Medicine identified a potential new drug that improved liver fibrosis in patients with NASH by 27%.

Defective closure of diabetic foot ulcers is associated with higher risk of wound recurrence

Indiana University — Mon, 26 Jun 2023 14:05:25 EST

Results from a new study of diabetic foot ulcers and the risk of wound recurrence show that a new approach can help health care workers measure the likelihood that the wound will reopen in the future.

The expanded Child Tax Credit led to improved health and nutrition among adults

University of California, Los Angeles (UCLA), Health Sciences — Sat, 24 Jun 2023 13:30:00 EST

Monthly cash payments to eligible families under the temporary pandemic-era expansion of the federal Child Tax Credit led to better adult health and food security, new UCLA-led research suggests.

SLU Medical Student Receives NIH F30 Grant to Explore Autoimmune Disease, Infection in the Stomach

Saint Louis University — Thu, 08 Jun 2023 17:00:57 EST

Stella Hoft, a M.D./Ph.D. student at Saint Louis University's School of Medicine, was recently awarded a F30 Grant through the National Institute of Diabetes & Digestive & Kidney Diseases.

SLU Researcher Receives $2.2 M to Study Link Between Inflammation, Gastric Cancer

Saint Louis University — Thu, 08 Jun 2023 16:30:39 EST

Rich DiPaolo, Ph.D., professor and interim chair in the Department of Molecular Microbiology and Immunology, warns that patients with gastritis caused by autoimmunity as well as Helicobacter pylori, a type of bacteria that infects your stomach, may benefit from routine screenings to identify patients with a high risk of progressing to gastric cancer.