News Feature Channel: Drug Resistance

An Innovative Antibiotic for Drug-Resistant Bacteria

American Chemical Society (ACS) — Wed, 20 Nov 2024 08:00:00 EST

Building on previous work, researchers in ACS Infectious Diseases have demonstrated a potential antibacterial treatment from a modified darobactin, a compound originally from a bacterium. The team reports proof-of-concept animal trials on infections caused by bacteria, including E. coli, that are known to develop drug resistance.

Zymo Research Leads the Way in Wastewater Innovation as Key Sponsor of the Microbes in Wastewater Symposium 2025

Zymo Research Corp — Mon, 18 Nov 2024 08:40:11 EST

Zymo Research Corporation, a global leader in innovative life science solutions, is proud to sponsor the Microbes in Wastewater: Antibiotic Resistance, Public Health, and Climate Change Symposium taking place January 16-17, 2025, in Newport Beach, California. This pivotal event will convene top researchers, industry experts, and public health professionals to explore the latest advancements in wastewater surveillance and its critical impact on public health, antibiotic resistance, and environmental sustainability.

Researchers Uncover Achilles Heel of Antibiotic-Resistant Bacteria

University of California San Diego — Fri, 15 Nov 2024 14:00:00 EST

To stem the surging antibiotic resistance public health crisis, scientists seek solutions inside the mechanics of bacterial infection. A new study has found a vulnerability related to magnesium availability. This limitation potentially could be exploited to stop the spread of antibiotic resistance.

Study Uncovers First Evidence of Resistance to Standard Malaria Treatment in African Children with Severe Malaria

Indiana University — Thu, 14 Nov 2024 14:45:34 EST

An international team of researchers has uncovered evidence of partial resistance to artemisinin derivatives -- the primary treatment for malaria -- in young children with severe malaria.

University of Chicago Medicine Comprehensive Cancer Center partners with Argonne National Laboratory to accelerate the discovery of new cancer therapies using AI

University of Chicago Medical Center — Thu, 14 Nov 2024 13:05:26 EST

Researchers at the UChicago Medicine Comprehensive Cancer Center and Argonne National Laboratory are partnering to use AI approaches to discover new targets for cancer therapies

Drug Combination Prompts Immune Response in Some Resistant Pancreatic Cancers

Johns Hopkins Medicine — Thu, 14 Nov 2024 10:00:23 EST

A new drug strategy that regulates the tumor immune microenvironment may transform a tumor that resists immunotherapy into a susceptible one, according to a study by researchers from the Johns Hopkins Kimmel Cancer Center and Oregon Health & Science University.

Researchers Reveal Why a Key Tuberculosis Drug Works Against Resistant Strains

Rutgers University-New Brunswick — Wed, 13 Nov 2024 18:35:09 EST

Rutgers Health study uncovers vulnerabilities in drug-resistant TB, offering hope for improved treatments.

KRISS Partners with Domestic University Hospitals to Develop Disease Diagnosis and Treatment Technology, Alleviating Patient Burden

National Research Council of Science and Technology — Wed, 13 Nov 2024 00:00:34 EST

The Korea Research Institute of Standards and Science (KRISS) announced that they have developed an advanced disease diagnosis and treatment system based on nanomaterials.

Trend of Antibiotic Resistance in Alzheimer's Needs Examining

Alzheimer's Center at Temple University Lewis Katz School of Medicine — Tue, 05 Nov 2024 11:25:05 EST

A review article entitled "Prevalence of Antibiotic Resistance in Older Adults and Alzheimer's Disease Patients: A Systematic Review and Meta-Analysis," is now published in the Journal Alzheimer's Disease Reports.

Mount Sinai Researchers Enhance Screening Methods to Prevent Spread of Drug-Resistant Fungal Infections in Hospitals

Mount Sinai Health System — Fri, 01 Nov 2024 09:05:04 EST

Expanded protocols promote early detection in high-risk patients and prevent hospital outbreaks of Candida auris

Research Shows New Method Helps Doctors Safely Remove Dangerous Heart Infections Without Surgery

Mayo Clinic — Wed, 30 Oct 2024 14:45:46 EST

Doctors at Mayo Clinic used a new catheter-based approach to draw out resistant pockets of infection that settle in the heart, known as right-sided infective endocarditis, without surgery. Unless treated quickly, the walled-off infections can grow, severely damaging heart valves and potentially affecting other organs as well. In a recent study, over 90% of the participants had their infection cleared, and they had lower in-hospital mortality compared to those whose infections remained.

Iowa State Study Shows Zinc's Potential to Fight Antimicrobial Resistance

Iowa State University — Mon, 28 Oct 2024 15:55:04 EST

A research team at Iowa State University has found that zinc supplements may be an inexpensive, effective antidote to the growing health threat of antimicrobial resistance, potentially extending the effectiveness of today's antibiotic arsenal against disease.

Encrypted Peptides, New Class of Antibiotics, Offer Hope in Fight Against Antibiotic Resistance

Perelman School of Medicine at the University of Pennsylvania — Mon, 28 Oct 2024 10:30:00 EST

In a significant advance against the growing threat of antibiotic-resistant bacteria, , researchers have identified a novel class of antimicrobial agents known as encrypted peptides, which may expand the immune system's arsenal of tools to fight infection.

Innovative Bioelectronic Device Offers New Hope in the Fight Against Bacterial Infections

University of California San Diego — Thu, 24 Oct 2024 10:00:20 EST

Researchers have developed a bioelectronic device that taps into the natural electrical activity of certain bacteria found on our skin, paving the way for a drug-free approach to managing infections. The advancement reduces the harmful effects of a bacterium known for antibiotic resistance.

Melanoma with Drug Resistance: Cause Identified

National Research Council of Science and Technology — Tue, 08 Oct 2024 09:00:05 EST

Key mechanism of resistance to BRAF-targeted melanoma therapy discovered. Potential for developing new cancer therapies with high efficacy by regulating polyamine biosynthesis to suppress resistance.

New Addition to Standard-of-Care Treatments for Non-Small-Cell Lung Cancer Patients Has Potential to Increase Progression-Free Survival

Houston Methodist — Thu, 03 Oct 2024 19:05:15 EST

Houston Methodist researchers have developed an advanced mathematical model that predicts how novel treatment combinations could significantly extend progression-free survival for patients with non-small-cell lung cancer (NSCLC), the most common type of lung cancer.

PCORI Awards $37 Million To Accelerate Implementation of Evidence-Based Health Research

Patient-Centered Outcomes Research Institute (PCORI) — Wed, 02 Oct 2024 11:05:44 EST

The Patient-Centered Outcomes Research Institute (PCORI) today announced $37 million in funding awards through its Health Systems Implementation Initiative (HSII). These awards will support 25 projects implementing PCORI-funded comparative clinical effectiveness research (CER) findings in participating HSII health systems.

UTHealth Houston's Minimally Invasive Treatment Extends Hope to Patients with Medication-Resistant Epilepsy

University of Texas Health Science Center at Houston — Wed, 25 Sep 2024 12:05:13 EST

Findings of a study on a novel and minimally invasive laser therapy for patients with drug-resistant epilepsy caused by periventricular nodular heterotopia (PNVH) have been published by UTHealth Houston researchers in American Neurological Association's Annals of Neurology.

Overcoming Drug Resistance in Breast Cancer Treatment

College of Liberal Arts and Sciences, University of Illinois Urbana-Champaign — Thu, 12 Sep 2024 17:05:28 EST

An interdisciplinary team of researchers from the University of Illinois has discovered a potential new treatment option for drug-resistant breast cancer. Their findings, published in Breast Cancer Research and Treatment, demonstrates the role of activators of ferroptosis in overcoming acquired resistance to FOXM1 inhibitors.

Mark Awad Named Chief of the Thoracic Oncology Service at Memorial Sloan Kettering Cancer Center

Memorial Sloan Kettering Cancer Center — Tue, 10 Sep 2024 09:00:00 EST

Mark Awad, MD, PhD, has been appointed Chief of the Thoracic Oncology Service within the Solid Tumor Oncology Division, Department of Medicine at Memorial Sloan Kettering Cancer Center (MSK).