News Feature Channel: Cancer

Silk Sponges Instead of Animal Testing: How a 3D Cell Culture System Could Revolutionize Cancer Diagnostics

University of Vienna — Fri, 21 Mar 2025 05:00:34 EST

An FFG-funded consortium of Austrian research groups from the University of Vienna, MedUni Vienna and Technikum Wien together with company partner DOC Medikus GmbH has developed an innovative bioanalytical test system for radiopharmaceutical drug candidates for cancer diagnosis and therapy. It does not require any animal testing at all and enables automated, fast and highly precise analyses. The new method was presented in detail in the renowned Journal of Nuclear Medicine.

AACI Letter Urges Secretary Kennedy, HHS to Protect Federal Funding for Cancer Research

Association of American Cancer Institutes (AACI) — Thu, 20 Mar 2025 20:05:15 EST

This week, the Association of American Cancer Institutes (AACI) delivered a letter to U.S. Department of Health & Human Services (HHS) Secretary Robert F. Kennedy, Jr., urging him to ensure stable, uninterrupted funding for the National Institutes of Health (NIH) and National Cancer Institute (NCI).

Six Things Parents Need to Know About CAR T-Cell Therapy for Cancer

Children's Hospital Los Angeles — Thu, 20 Mar 2025 19:30:47 EST

What happens when cancer doesn't respond to chemotherapy? A revolutionary therapy called chimeric antigen receptor (CAR) T-cell therapy uses a person's own immune cells that have been modified to recognize and attack cancer cells.

Childhood Leukemia Isn't What It Used to Be: Latest Treatments, Research, and Reasons to Hope

Children's Hospital Los Angeles — Thu, 20 Mar 2025 17:50:50 EST

Hearing the word "leukemia" can be alarming in any context. Hearing it in the context of your child's health might feel terrifying, unfair, and even hopeless. But according to leading pediatric leukemia experts, families grappling with the news of a diagnosis have reason to feel .Today, for a great majority of pediatric leukemia cases, a new diagnosis doesn't mean what it meant 30, 20, or even 10 years ago.

New Guidelines Expanded Access to Lung Cancer Screening, But Gaps Remain in Reaching Rural and Uninsured Populations

Sylvester Comprehensive Cancer Center — Thu, 20 Mar 2025 11:00:00 EST

Since 2021, when lung cancer screening guidelines began to include younger people and those with a lower smoking history, the number of screenings climbed, but significant gaps remain, especially among people with limited access to healthcare.

Analysis of New Colorectal Cancer Immunotherapy Shows More Treatment Options

Cleveland Clinic — Thu, 20 Mar 2025 11:00:00 EST

A team of researchers from Cleveland Clinic Genomic Medicine share insights from an early set of 19,000 patients to receive immune checkpoint inhibitor treatments for colorectal cancer in the U.S. The report comes from the laboratory of Stephanie Schmit, PhD, MPH, and was published in JAMA Network Open. It serves as an opportunity to better understand how immune checkpoint inhibitor treatments, including PD-1 and PD-L1 inhibitors, work in a larger population that reflects real-world settings. Dr. Schmit collaborated with a team of researchers that included Moffitt Cancer Center.

Potential Targeted Therapy for Pediatric Brain Cancer Identified by Dana-Farber Team

Dana-Farber Cancer Institute — Thu, 20 Mar 2025 09:00:39 EST

An international team of clinical collaborators, led by physician scientists from Dana-Farber Cancer Institute, performed a first-ever clinical test of the targeted therapy avapritinib in pediatric and young patients with a form of high-grade glioma. They found that the drug, already FDA-approved for certain adult cancers, was generally safe and resulted in tumor reduction visible on brain scans, as well as clinical improvement, in 3 out of 7 patients.

Caris Life Sciences Publishes Study Featuring the Largest Real-World Cohort of Tissue-Agnostic Indications Revealing Over 20 Percent of Patients Are Eligible for "Pan-Cancer" Therapies

Life Sciences — Thu, 20 Mar 2025 06:40:57 EST

Caris Life Sciences(r) (Caris), a leading next-generation AI TechBio company and precision medicine pioneer, today announced the publication of "Real-world evidence provides clinical insights into tissue-agnostic therapeutic approvals" in Nature Communications.

Nemours Children's Health Opens Lisa Dean Moseley Foundation Institute for Cancer and Blood Disorders

Nemours Children's Health — Wed, 19 Mar 2025 20:20:12 EST

Nemours Children's Health Opens Lisa Dean Moseley Foundation Institute for Cancer and Blood Disorders

Owen Witte awarded international Harrington Prize for Innovation in Medicine

University of California, Los Angeles (UCLA), Health Sciences — Wed, 19 Mar 2025 20:15:12 EST

The Harrington Discovery Institute at University Hospitals and the American Society for Clinical Investigation have awarded Dr. Owen Witte(Link is external) (Link opens in new window) with the twelfth annual Harrington Prize for Innovation in Medicine.

Removing a Protein 'Signal Jammer' Improves Immunotherapy

St. Jude Children's Research Hospital — Wed, 19 Mar 2025 19:55:58 EST

Find how a mitochondrial protein protects cancer cells from immunotherapy, giving scientists a new target type to improve solid tumor treatment & save lives.

Investigadores de Mayo Clinic identifican proteinas relacionadas con la resistencia a la inmunoterapia en el cancer colorrectal metastasico

Mayo Clinic — Wed, 19 Mar 2025 19:55:44 EST

Un descubrimiento realizado por investigadores de Mayo Clinic puede ayudar a explicar por que la inmunoterapia no ha sido util para muchos pacientes con cancer colorrectal metastasico. En los descubrimientos publicados en Clinical Cancer Research, el equipo identifico proteinas especificas -- fibronectina y actina del musculo liso -- dentro de los tejidos del cancer colorrectal que estan asociadas con la resistencia al tratamiento de inmunoterapia.

Pesquisadores da Mayo Clinic identificam proteinas ligadas a resistencia a imunoterapia no cancer colorretal metastatico

Mayo Clinic — Wed, 19 Mar 2025 19:45:23 EST

Uma descoberta feita por pesquisadores da Mayo Clinic pode ajudar a explicar por que a imunoterapia nao tem sido util para muitos pacientes com cancer colorretal metastatico. Nas descobertas publicadas na Clinical Cancer Research, a equipe identificou proteinas especificas -- fibronectina e actina do musculo liso -- dentro dos tecidos do cancer colorretal que estao associados a resistencia ao tratamento imunoterapico.

Mayo Clinic Researchers Identify a Measurable Genetic Mutation as a Significant Predictor of Metastasis and Survival in Pancreatic Cancer

Mayo Clinic — Wed, 19 Mar 2025 18:50:37 EST

A new study by Mayo Clinic Comprehensive Cancer Center researchers found that the presence of a specific genetic mutation -- KRAS circulating tumor DNA (ctDNA) -- strongly indicates a higher risk of cancer spread and worse survival rates for patients with pancreatic ductal adenocarcinoma (PDAC). The mutation was identified using a readily available and clinically approved blood and abdominal fluid test.

AI Helps Find Promising Therapeutic Target for Rare Salivary Gland Cancer

University of Chicago Medical Center — Wed, 19 Mar 2025 18:15:54 EST

Researchers have uncovered a promising therapeutic target for adenoid cystic carcinoma (ACC), a rare cancer of the salivary glands with few treatment options. The study found that blocking the activity of protein arginine methyl transferase 5 (PRMT5) is a potential treatment strategy against ACC.

Foods to Fortify

University of Miami — Wed, 19 Mar 2025 17:20:15 EST

Experts in nutrition science from across the University of Miami offer their thoughts on some of the best foods to help us ward off chronic disease.

Accessing Community Support and Resources for Breast Cancer Patients

Mercy Medical Center — Tue, 18 Mar 2025 20:35:37 EST

Accessing Community Support and Resources for Breast Cancer Patients

Moffitt Study Finds Vaccine May Improve Breast Cancer Treatment Outcomes

Moffitt Cancer Center — Tue, 18 Mar 2025 20:25:56 EST

Moffitt Cancer Center researchers have discovered a promising new vaccine strategy for treating a specific type of breast cancer. The innovative approach targets human epidermal growth factor receptor 2-positive, estrogen receptor-negative (HER2-positive, ER-negative) breast cancer and has shown encouraging results in a recent pilot study. Published in npj Breast Cancer, the study combined the HER2-targeting dendritic cell vaccines with standard chemotherapy, demonstrating both safety and positive response rates.

Study Confirms Safety and Efficacy of Higher-Dose-Per-Day Radiation for Early-Stage Prostate Cancer

University of California, Los Angeles (UCLA), Health Sciences — Tue, 18 Mar 2025 18:40:09 EST

A new large-scale study provides the strongest evidence yet that a shorter, standard-dose course radiation treatment is just as effective as conventional radiotherapy for prostate cancer, without compromising the safety of patients.

Rutgers Launches Center to Tackle Barriers to Weight Loss and Other Causes of Disease

Rutgers Robert Wood Johnson Medical School — Tue, 18 Mar 2025 18:30:03 EST

Rutgers Launches Center to Tackle Barriers to Weight Loss and Other Causes of Disease