News Â鶹´«Ã½ from St. Jude Children's Research Hospital display Latest news from St. Jude Children's Research Hospital on News en-us Copyright 2024 News News Â鶹´«Ã½ from St. Jude Children's Research Hospital 115 31 / /images/newswise-logo-rss.gif Glutamine Metabolic Switch Is Key to Red Blood Cell Development and Disease /articles/glutamine-metabolic-switch-is-key-to-red-blood-cell-development-and-disease/?sc=rsin /articles/glutamine-metabolic-switch-is-key-to-red-blood-cell-development-and-disease/?sc=rsin Fri, 15 Nov 2024 10:45:03 EST Scientists at St. Jude Children's Research Hospital identified a link between glutamine metabolism and red blood cell maturation, showing how disruption of the process can drive disease. St. Jude Children's Research Hospital Tumor Suppressor Forms Gel-Like Assemblies to Sacrifice Cancer Cells /articles/tumor-suppressor-forms-gel-like-assemblies-to-sacrifice-cancer-cells/?sc=rsin /articles/tumor-suppressor-forms-gel-like-assemblies-to-sacrifice-cancer-cells/?sc=rsin Mon, 11 Nov 2024 14:30:35 EST Scientists at St. Jude Children's Research Hospital have uncovered a previously unrecognized tumor suppression mechanism through the study of condensates and ribosome formation. St. Jude Children's Research Hospital Mitchell Weiss of St. Jude Children's Research Hospital elected to the National Academy of Medicine /articles/mitchell-weiss-of-st-jude-children-s-research-hospital-elected-to-the-national-academy-of-medicine/?sc=rsin /articles/mitchell-weiss-of-st-jude-children-s-research-hospital-elected-to-the-national-academy-of-medicine/?sc=rsin Thu, 24 Oct 2024 10:00:26 EST Leading expert in catastrophic blood disorders becomes the seventh St. Jude faculty member tapped for this honor. St. Jude Children's Research Hospital St. Jude ranks in top 10 of U.S. Â鶹´«Ã½ Best Children's Hospitals for Cancer /articles/st-jude-ranks-in-top-10-of-u-s-news-best-children-s-hospitals-for-cancer/?sc=rsin /articles/st-jude-ranks-in-top-10-of-u-s-news-best-children-s-hospitals-for-cancer/?sc=rsin Wed, 09 Oct 2024 16:30:45 EST St. Jude Children's Research Hospital was recognized as one of the top 10 pediatric cancer hospitals for the 17th straight year by U.S. Â鶹´«Ã½ & World Report. Every year since 2008, the publication has evaluated about 100 hospitals with pediatric oncology programs and ranked the top 50 as part of its annual list of Best Children's Hospitals. St. Jude Children's Research Hospital St. Jude Names M. Madan Babu, PhD, Senior Vice President and Chief Data Scientist /articles/st-jude-names-m-madan-babu-phd-senior-vice-president-and-chief-data-scientist/?sc=rsin /articles/st-jude-names-m-madan-babu-phd-senior-vice-president-and-chief-data-scientist/?sc=rsin Tue, 01 Oct 2024 12:20:36 EST In his new role, Babu will bring new, advanced computing technologies and data science approaches to biomedical research. His team will also facilitate the integration of biological and biomedical data, foster a data science research culture, and build international collaborations. St. Jude Children's Research Hospital Structure of a Eukaryotic CRISPR-Cas homolog, Fanzor2, Shows Its Promise for Gene Editing /articles/structure-of-a-eukaryotic-crispr-cas-homolog-fanzor2-shows-its-promise-for-gene-editing/?sc=rsin /articles/structure-of-a-eukaryotic-crispr-cas-homolog-fanzor2-shows-its-promise-for-gene-editing/?sc=rsin Tue, 01 Oct 2024 12:05:58 EST See how structures of Fanzor2, a relation of the transposon family TnpB, show how the protein can be used in genome engineering technology like CRISPR-Cas9. St. Jude Children's Research Hospital Clinical Trial Results Show Low-Intensity Therapy Can Achieve Positive Outcomes for Certain Pediatric Leukemia Subtypes /articles/clinical-trial-results-show-low-intensity-therapy-can-achieve-positive-outcomes-for-certain-pediatric-leukemia-subtypes/?sc=rsin /articles/clinical-trial-results-show-low-intensity-therapy-can-achieve-positive-outcomes-for-certain-pediatric-leukemia-subtypes/?sc=rsin Tue, 24 Sep 2024 16:05:00 EST Using genomics and early treatment response to guide risk-stratification and low-intensity therapy use for ETV6::RUNX1 and high-hyperdiploid B-cell acute lymphoblastic leukemia benefits patients. St. Jude Children's Research Hospital Urate Transporter Structures Reveal the Mechanism Behind Important Drug Target for Gout /articles/urate-transporter-structures-reveal-the-mechanism-behind-important-drug-target-for-gout/?sc=rsin /articles/urate-transporter-structures-reveal-the-mechanism-behind-important-drug-target-for-gout/?sc=rsin Mon, 09 Sep 2024 11:05:22 EST Ten structures of URAT1 obtained by scientists at St. Jude Children's Research Hospital provide a deep understanding of the mechanism of urate transport to guide gout therapeutic design. St. Jude Children's Research Hospital Early interventions may improve long-term academic achievement in young childhood brain tumor survivors /articles/early-interventions-may-improve-long-term-academic-achievement-in-young-childhood-brain-tumor-survivors/?sc=rsin /articles/early-interventions-may-improve-long-term-academic-achievement-in-young-childhood-brain-tumor-survivors/?sc=rsin Wed, 21 Aug 2024 12:05:25 EST Scientists at St. Jude Children's Research Hospital found infants and young children treated for brain tumors fell behind early in academic readiness, which predicted falling behind in later school years. St. Jude Children's Research Hospital T helper cells may be the key to improving annual influenza vaccines /articles/t-helper-cells-may-be-the-key-to-improving-annual-influenza-vaccines/?sc=rsin /articles/t-helper-cells-may-be-the-key-to-improving-annual-influenza-vaccines/?sc=rsin Tue, 20 Aug 2024 10:05:28 EST The annual influenza vaccination provides updated protection against the virus but could be improved as there is large variability in its efficacy. St. Jude Children's Research Hospital Study reveals oleoyl-ACP-hydrolase underpins lethal respiratory viral disease /articles/study-reveals-oleoyl-acp-hydrolase-underpins-lethal-respiratory-viral-disease/?sc=rsin /articles/study-reveals-oleoyl-acp-hydrolase-underpins-lethal-respiratory-viral-disease/?sc=rsin Mon, 12 Aug 2024 13:30:50 EST Respiratory infections can be severe, even deadly, in some individuals, but not in others. Scientists at St. Jude Children's Research Hospital, the Peter Doherty Institute for Infection and Immunity and other collaborators have gained new understanding of why this is the case by uncovering an early molecular driver that underpins fatal disease. St. Jude Children's Research Hospital Scientists identify genes linked to relapse in the most common form of childhood leukemia /articles/scientists-identify-genes-linked-to-relapse-in-the-most-common-form-of-childhood-leukemia/?sc=rsin /articles/scientists-identify-genes-linked-to-relapse-in-the-most-common-form-of-childhood-leukemia/?sc=rsin Mon, 12 Aug 2024 11:50:31 EST Scientists from St. Jude Children's Research Hospital, Seattle Children's and the Children's Oncology Group (COG) have identified novel genetic variations that influence relapse risk in children with standard risk B-cell acute lymphoblastic leukemia (SR B-ALL), the most common childhood cancer. St. Jude Children's Research Hospital St. Jude identifies SARS-CoV-2 "mimic" contributing to pediatric inflammatory syndrome /articles/st-jude-identifies-sars-cov-2-mimic-contributing-to-pediatric-inflammatory-syndrome/?sc=rsin /articles/st-jude-identifies-sars-cov-2-mimic-contributing-to-pediatric-inflammatory-syndrome/?sc=rsin Wed, 07 Aug 2024 13:05:07 EST Discover St. Jude research from Paul Thomas, PhD, linking SARS-CoV-2 infections and molecular mimicry with multisystem inflammatory syndrome in children. St. Jude Children's Research Hospital Genetic 'episignatures' guide researchers in identifying causes of unsolved epileptic neurological disorders /articles/genetic-episignatures-guide-researchers-in-identifying-causes-of-unsolved-epileptic-neurological-disorders/?sc=rsin /articles/genetic-episignatures-guide-researchers-in-identifying-causes-of-unsolved-epileptic-neurological-disorders/?sc=rsin Tue, 06 Aug 2024 15:05:51 EST Scientists at St. Jude Children's Research Hospital use DNA methylation patterns as a roadmap for identifying causes of severe epilepsies in children. St. Jude Children's Research Hospital Age impacts pharmacogenomics and treatment outcomes for most common form of leukemia /articles/age-impacts-pharmacogenomics-and-treatment-outcomes-for-most-common-form-of-leukemia/?sc=rsin /articles/age-impacts-pharmacogenomics-and-treatment-outcomes-for-most-common-form-of-leukemia/?sc=rsin Mon, 05 Aug 2024 17:05:57 EST Explore how scientists at St. Jude Children's Research Hospital have identified causes for age-related differences in treatment outcomes of B-cell acute lymphoblastic leukemia. St. Jude Children's Research Hospital Improved chemokine homing enhances CAR T-cell therapy for osteosarcoma /articles/improved-chemokine-homing-enhances-car-t-cell-therapy-for-osteosarcoma/?sc=rsin /articles/improved-chemokine-homing-enhances-car-t-cell-therapy-for-osteosarcoma/?sc=rsin Mon, 05 Aug 2024 12:05:38 EST Learn how scientists at St. Jude are leading research to improve CAR T-cell therapy for osteosarcoma by enhancing chemokine homing. St. Jude Children's Research Hospital Serotonin uptake regulates ependymoma tumor growth /articles/serotonin-uptake-regulates-ependymoma-tumor-growth/?sc=rsin /articles/serotonin-uptake-regulates-ependymoma-tumor-growth/?sc=rsin Wed, 31 Jul 2024 14:05:46 EST St. Jude Children's Research Hospital and Baylor College of Medicine have implicated the neurotransmitter serotonin in ependymoma tumor growth, suggesting a new class of drugs to test against these tumors. St. Jude Children's Research Hospital Biomolecular condensate 'molecular putty' properties found encoded in protein sequence /articles/biomolecular-condensate-molecular-putty-properties-found-encoded-in-protein-sequence/?sc=rsin /articles/biomolecular-condensate-molecular-putty-properties-found-encoded-in-protein-sequence/?sc=rsin Tue, 02 Jul 2024 12:05:02 EST Scientists at St. Jude Children's Research Hospital, the State University of New York at Buffalo and Washington University at St. Louis probed how condensates behave like viscoelastic putty and age to more solid states. St. Jude Children's Research Hospital Master autoimmune regulator gets by with a little help from its friends /articles/master-autoimmune-regulator-gets-by-with-a-little-help-from-its-friends/?sc=rsin /articles/master-autoimmune-regulator-gets-by-with-a-little-help-from-its-friends/?sc=rsin Thu, 27 Jun 2024 13:05:46 EST See how St. Jude researchers investigated Foxp3 function as a transcription cofactor in regulatory T cells in immune system activation and suppression. St. Jude Children's Research Hospital Children genetically prone to cancer benefit from early standardized surveillance /articles/children-genetically-prone-to-cancer-benefit-from-early-standardized-surveillance/?sc=rsin /articles/children-genetically-prone-to-cancer-benefit-from-early-standardized-surveillance/?sc=rsin Thu, 20 Jun 2024 12:05:21 EST Scientists at St. Jude Children's Research Hospital found that, with early screening, they could detect new cancers in pediatric patients with an underlying genetic predisposition at their most treatable stages. St. Jude Children's Research Hospital