Latest news from UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research on News en-us Copyright 2024 News 115 31 / /images/newswise-logo-rss.gif /articles/creatine-powers-t-cells-fight-against-cancer/?sc=rsin /articles/creatine-powers-t-cells-fight-against-cancer/?sc=rsin Fri, 18 Oct 2019 12:05:40 EST The study, conducted in mice, is the first to show that creatine uptake is critical to the anti-tumor activities of killer T cells, the foot soldiers of the immune system. UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research /articles/antibody-eradicates-leukemia-stem-cells/?sc=rsin /articles/antibody-eradicates-leukemia-stem-cells/?sc=rsin Tue, 15 Oct 2019 12:05:08 EST Now, in experiments in mice as well as isolated human cancer cells, UCLA researchers have discovered a way to eliminate the CML stem cells. Their approach uses an antibody to block a protein that the stem cells rely on to grow. The advance, described in a study published in the Journal of Clinical Investigation, might eventually help treat not only chronic myelogenous leukemia but other cancers as well. UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research /articles/researchers-identify-molecular-process-that-could-accelerate-recovery-from-nerve-injuries/?sc=rsin /articles/researchers-identify-molecular-process-that-could-accelerate-recovery-from-nerve-injuries/?sc=rsin Wed, 02 Oct 2019 11:05:08 EST Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have discovered a molecular process that controls the rate at which nerves grow both during embryonic development and recovery from injury throughout life. UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research /articles/ucla-study-overturns-dogma-of-cancer-metabolism-theory-tumors-not-as-addicted-to-glucose-as-previously-thought/?sc=rsin /articles/ucla-study-overturns-dogma-of-cancer-metabolism-theory-tumors-not-as-addicted-to-glucose-as-previously-thought/?sc=rsin Wed, 09 Jan 2019 14:05:37 EST Scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have discovered that squamous cell skin cancers do not require increased glucose to power their development and growth, contrary to a long-held belief about cancer metabolism. The findings could bring about a better understanding of many cancers' metabolic needs and lead to the development of more effective therapies for squamous cell skin cancer and other forms of epithelial cancer. UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research /articles/research-redefines-proteins-role-in-the-development-of-spinal-sensory-cells/?sc=rsin /articles/research-redefines-proteins-role-in-the-development-of-spinal-sensory-cells/?sc=rsin Tue, 19 Sep 2017 13:05:49 EST A recent study led by Samantha Butler at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA has overturned a common belief about how a certain class of proteins in the spinal cord regulate the formation of nervous system cells--called neurons--during embryonic development. UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research /articles/ucla-researchers-receive-prestigious-cirm-tools-and-technologies-award/?sc=rsin /articles/ucla-researchers-receive-prestigious-cirm-tools-and-technologies-award/?sc=rsin Mon, 02 Feb 2015 11:00:00 EST Two scientists from the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have received a California Institute of Regenerative Medicine (CIRM) Tools and Technology Award that will forward revolutionary stem cell medicine. The UCLA researchers were among only 20 scientists nationwide to receive the Tools and Technologies Award, the most of any institution represented. UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research /articles/growing-bone-in-space-ucla-and-casis-announce-pioneering-collaborative-study-to-test-therapy-for-bone-loss-on-the-international-space-station/?sc=rsin /articles/growing-bone-in-space-ucla-and-casis-announce-pioneering-collaborative-study-to-test-therapy-for-bone-loss-on-the-international-space-station/?sc=rsin Thu, 22 Jan 2015 09:00:00 EST Center for Advancement of Science in Space (CASIS) awarded grant funding to UCLA for stem cell researchers to send rodents into space to test new therapy for prevention of bone loss. Research has enormous translational potential for astronauts in space flight and patients on Earth with osteoporosis or other bone loss problems from disease, illness or trauma. UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research /articles/scientists-develop-pioneering-method-to-define-stages-of-stem-cell-reprogramming2/?sc=rsin /articles/scientists-develop-pioneering-method-to-define-stages-of-stem-cell-reprogramming2/?sc=rsin Mon, 05 Jan 2015 12:00:00 EST UCLA researchers have for the first time developed a method that defines many stages of reprogramming skin or blood cells into pluripotent stem cells. Study analyzed the reprogramming process at the single-cell level on a daily basis. Results determined that stages of cell change were the same across different reprogramming systems and cell types analyzed. UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research /articles/ucla-researchers-unlock-protein-key-to-harnessing-regenerative-power-of-blood-stem-cells/?sc=rsin /articles/ucla-researchers-unlock-protein-key-to-harnessing-regenerative-power-of-blood-stem-cells/?sc=rsin Mon, 24 Nov 2014 12:00:00 EST UCLA scientists have discovered a protein which is integral to the regulation of human blood stem cell regeneration. Study revealed that stem cells which lack the protein have markedly increased ability to replicate in vivo and following transplantation. Discovery provides new understanding of human stem cell self-renewal and paves the way for targeted therapies to make stem cells grow. UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research /articles/ucla-stem-cell-researcher-pioneers-gene-therapy-cure-for-children-with-bubble-baby-disease/?sc=rsin /articles/ucla-stem-cell-researcher-pioneers-gene-therapy-cure-for-children-with-bubble-baby-disease/?sc=rsin Tue, 18 Nov 2014 14:00:00 EST UCLA stem cell researchers cured 18 children born without a working immune system due to life-threatening ADA-deficient Severe Combined Immunodeficiency (SCID). Breakthrough stem cell gene therapy developed by Dr. Donald Kohn and team identifies and corrects faulty gene in children with ADA-deficient SCID using child's own cells. UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research /articles/ucla-researchers-identify-unique-protein-key-to-the-development-of-blood-stem-cells/?sc=rsin /articles/ucla-researchers-identify-unique-protein-key-to-the-development-of-blood-stem-cells/?sc=rsin Thu, 13 Nov 2014 12:00:00 EST UCLA stem cell scientists discover unique cell surface protein GPI-80 that is key to self-renewal of hematopoietic (blood forming) stem cells (HSCs) during human development. Discovery paves the way for scientists to distinguish HSCs from their short-lived daughter cells and identify the unique properties that enable them to self-renew. UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research /articles/ucla-gene-discovery-shows-how-stem-cells-can-be-activated-to-help-immune-system-respond-to-infection/?sc=rsin /articles/ucla-gene-discovery-shows-how-stem-cells-can-be-activated-to-help-immune-system-respond-to-infection/?sc=rsin Thu, 30 Oct 2014 12:00:00 EST UCLA scientists show that two genes not previously known to be involved with the immune system play an active role in directing stem cells to fight infection UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research /articles/scientists-propose-benchmark-to-better-replicate-natural-stem-cell-development-in-the-laboratory-environment/?sc=rsin /articles/scientists-propose-benchmark-to-better-replicate-natural-stem-cell-development-in-the-laboratory-environment/?sc=rsin Fri, 24 Oct 2014 16:00:00 EST UCLA researchers have developed a benchmark to assess how well stem cell culture conditions in the lab resemble counterparts in the developing embryo UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research /articles/ucla-and-uci-awarded-8m-grant-to-launch-collaborative-stem-cell-clinic-center-of-excellence/?sc=rsin /articles/ucla-and-uci-awarded-8m-grant-to-launch-collaborative-stem-cell-clinic-center-of-excellence/?sc=rsin Thu, 23 Oct 2014 14:00:00 EST Two world renowned research universities and regional partners will join forces with $8M grant from the California Institute for Regenerative Medicine (CIRM) to create UCLA and UC Irvine Alpha Stem Cell Clinic Consortium UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research /articles/discovery-of-repair-process-after-heart-attack-suggests-potential-for-new-treatment-strategy/?sc=rsin /articles/discovery-of-repair-process-after-heart-attack-suggests-potential-for-new-treatment-strategy/?sc=rsin Wed, 15 Oct 2014 13:00:00 EST UCLA stem cell researcher Dr. Arjun Deb has discovered that some scar-forming cells in the heart, known as fibroblasts, have the ability to become endothelial cells (the cells that form blood vessels), and this study can point the way toward a new strategy for treating patients after a heart attack. UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research /articles/four-ucla-scientists-receive-prestigious-innovator-award-for-pioneering-research-using-stem-cells/?sc=rsin /articles/four-ucla-scientists-receive-prestigious-innovator-award-for-pioneering-research-using-stem-cells/?sc=rsin Fri, 10 Oct 2014 15:00:00 EST Four scientists from the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have received a National Institutes of Health (NIH) Director's New Innovator Award of $2.3 million per researcher, that will forward revolutionary stem cell and neuro-science in medicine. UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research