Latest news from Wistar Institute on News en-us Copyright 2025 News 115 31 / /images/newswise-logo-rss.gif /articles/scientists-demonstrate-pre-clinical-proof-of-concept-for-next-gen-dna-delivery-technology/?sc=rsin /articles/scientists-demonstrate-pre-clinical-proof-of-concept-for-next-gen-dna-delivery-technology/?sc=rsin Fri, 21 Mar 2025 11:05:00 EST Wistar Institute scientists and collaborators describe a next-generation vaccination technology that combines plasmid DNA with a lipid nanoparticle delivery system. Wistar Institute /articles/wistar-scientists-discover-a-promising-brain-cancer-target/?sc=rsin /articles/wistar-scientists-discover-a-promising-brain-cancer-target/?sc=rsin Fri, 28 Feb 2025 18:35:09 EST Filippo Veglia, Ph.D., and lab have discovered the process of how brain tumors reprogram certain immune cells called neutrophils from cancer enemies to cancer allies. Wistar Institute /articles/recruitment-of-first-caspar-wistar-fellow-to-join-hiv-cure-and-viral-diseases-center/?sc=rsin /articles/recruitment-of-first-caspar-wistar-fellow-to-join-hiv-cure-and-viral-diseases-center/?sc=rsin Fri, 28 Feb 2025 10:05:38 EST Colby Maldini, Ph.D., who joins Wistar's HIV Cure and Viral Diseases Center as a Caspar Wistar Fellow Wistar Institute /articles/scientists-at-the-wistar-institute-s-hiv-cure-and-viral-diseases-center-develop-new-natural-killer-cell-strategy-to-target-hiv/?sc=rsin /articles/scientists-at-the-wistar-institute-s-hiv-cure-and-viral-diseases-center-develop-new-natural-killer-cell-strategy-to-target-hiv/?sc=rsin Mon, 17 Feb 2025 19:20:54 EST Researchers at The Wistar Institute's HIV Cure and Viral Diseases Center have successfully identified a new approach using natural killer (NK) cells to target and kill the HIV-positive cells that allow the virus to persist. Wistar scientists have labeled this new approach "NuKES": Natural Killer Enhancement Strategy. Wistar Institute /articles/the-wistar-institute-scientists-discover-new-weapon-to-fight-treatment-resistant-melanoma/?sc=rsin /articles/the-wistar-institute-scientists-discover-new-weapon-to-fight-treatment-resistant-melanoma/?sc=rsin Wed, 05 Feb 2025 19:50:57 EST The Wistar Institute scientists have identified a new strategy for attacking treatment-resistant melanoma: inhibiting the gene S6K2. Wistar Institute /articles/the-wistar-institute-receives-two-biomedical-research-grants-from-the-v-foundation-for-cancer-researchgrants-fund-projects-aimed-at-improving-cancer-therapy-the-wistar-institute-receives-two-biomedical-research-grants-from-the-v-foundation-for-cancer-rese/?sc=rsin /articles/the-wistar-institute-receives-two-biomedical-research-grants-from-the-v-foundation-for-cancer-researchgrants-fund-projects-aimed-at-improving-cancer-therapy-the-wistar-institute-receives-two-biomedical-research-grants-from-the-v-foundation-for-cancer-rese/?sc=rsin Tue, 10 Dec 2024 13:00:36 EST Wistar Institute assistant professors Nan Zhang, Ph.D., and Noam Auslander Ph.D., have both received independent funding totaling $1.2 million over the next three years for cancer research projects from the V Foundation for Cancer Research. Wistar Institute /articles/wistar-institute-researchers-design-novel-immunotherapy-for-brain-cancer/?sc=rsin /articles/wistar-institute-researchers-design-novel-immunotherapy-for-brain-cancer/?sc=rsin Tue, 03 Dec 2024 11:55:34 EST The Wistar Institute's David B. Weiner, Ph.D., and his laboratory created a new therapeutic design for glioblastoma, the deadliest form of brain cancer. The lab engineered molecules called trispecifics that connect cancer-killing T cells with not just one but two different brain cancer receptors. Wistar Institute /articles/wistar-institute-scientists-identify-important-factor-in-neural-development/?sc=rsin /articles/wistar-institute-scientists-identify-important-factor-in-neural-development/?sc=rsin Tue, 26 Nov 2024 17:00:00 EST The Wistar Institute's Dr. Alessandro Gardini and his lab have published their new paper, "The enhancer module of integrator controls cell identity and early neural fate commitment," in the journal Nature Cell Biology. Wistar Institute /articles/wistar-institute-researchers-discover-new-combination-therapy-approach-for-metastatic-ovarian-cancer/?sc=rsin /articles/wistar-institute-researchers-discover-new-combination-therapy-approach-for-metastatic-ovarian-cancer/?sc=rsin Thu, 21 Nov 2024 13:15:28 EST The Wistar Institute scientists have discovered a new approach to treating ovarian cancer that, in preclinical laboratory testing, shrinks tumors and improves survival rates while simultaneously making tumors more receptive to chemotherapy treatment. Wistar Institute /articles/wistar-institute-and-cameroon-researchers-reveals-hiv-latency-reversing-properties-in-african-plant/?sc=rsin /articles/wistar-institute-and-cameroon-researchers-reveals-hiv-latency-reversing-properties-in-african-plant/?sc=rsin Tue, 19 Nov 2024 13:55:23 EST A collaboration between The Wistar Institute and the University of Buea in Cameroon has uncovered the mechanisms for a medicinal plant with anti-HIV potential in Croton oligandrus Pierre & Hutch, a species of African tree that has been used in traditional healing in Cameroon to treat a variety of diseases and conditions including cancers and diabetes. Wistar Institute /articles/the-wistar-institute-s-education-and-training-center-receives-100-000-niimbl-experience-grant/?sc=rsin /articles/the-wistar-institute-s-education-and-training-center-receives-100-000-niimbl-experience-grant/?sc=rsin Thu, 14 Nov 2024 14:40:04 EST The Wistar Institute's Hubert J.P. Schoemaker Education and Training Center was the recipient of a $100,000 eXperience grant from NIIMBL to support an immersive weeklong training program at the Institute. Wistar Institute /articles/scientists-at-the-wistar-institute-discover-novel-series-of-sars-cov-2-mpro-inhibitors-for-potential-new-covid-19-treatments/?sc=rsin /articles/scientists-at-the-wistar-institute-discover-novel-series-of-sars-cov-2-mpro-inhibitors-for-potential-new-covid-19-treatments/?sc=rsin Tue, 08 Oct 2024 09:05:52 EST New research from the Salvino lab identifies novel series of MPro inhibitors Wistar Institute /articles/wistar-institute-researchers-identify-parkinson-related-protein-s-role-in-cancer-and-t-cell-activation/?sc=rsin /articles/wistar-institute-researchers-identify-parkinson-related-protein-s-role-in-cancer-and-t-cell-activation/?sc=rsin Tue, 17 Sep 2024 14:05:48 EST Wistar scientists have demonstrated the role of Parkin -- a protein implicated in Parkinson's disease -- in the body's innate immune response to cancer. Wistar Institute /articles/scientists-at-the-wistar-institute-clone-several-new-anti-interferon-antibodies-developing-future-therapeutic-candidates-with-broad-application-potential/?sc=rsin /articles/scientists-at-the-wistar-institute-clone-several-new-anti-interferon-antibodies-developing-future-therapeutic-candidates-with-broad-application-potential/?sc=rsin Tue, 17 Sep 2024 14:05:21 EST Wistar Institute scientists have successfully isolated and cloned fully human antibodies that can block specific Type-I interferon molecules in vitro; their discovery has an array of potential clinical & research applications, enabling scientists with a new way to investigate the role of specific Type-I interferons in a variety of diseases. Wistar Institute /articles/the-wistar-institute-grows-research-enterprise-signs-new-lease-at-ucity-square/?sc=rsin /articles/the-wistar-institute-grows-research-enterprise-signs-new-lease-at-ucity-square/?sc=rsin Tue, 13 Aug 2024 10:00:00 EST The Wistar Institute and Wexford Science & Technology, LLC, announced that Wistar has signed a lease for new laboratory and office space at uCity Square in Philadelphia to expand its capacity and resources essential for making groundbreaking discoveries that advance human health. Wistar Institute /articles/wistar-celebrates-accomplishments-of-diverse-next-gen-students-pre-apprentices-completing-summer-science-education-training-programs/?sc=rsin /articles/wistar-celebrates-accomplishments-of-diverse-next-gen-students-pre-apprentices-completing-summer-science-education-training-programs/?sc=rsin Thu, 01 Aug 2024 10:05:11 EST Wistar Celebrates Accomplishments of 58 Diverse, Next-Gen Students & Pre-apprentices Completing Summer Science Education & Training Programs. Wistar Institute /articles/wistar-to-honor-2023-nobel-prize-winner-dr-katalin-karik/?sc=rsin /articles/wistar-to-honor-2023-nobel-prize-winner-dr-katalin-karik/?sc=rsin Thu, 25 Jul 2024 11:05:02 EST Wistar Institute honors 2023 Nobel laureate Katalin Kariko, Ph.D., as the 2024 Helen Dean King Award recipient on October 8, 2024 at noon (ET). Wistar Institute /articles/nobel-laureate-drew-weissman-m-d-ph-d-delivers-28th-annual-jonathan-lax-memorial-lecture-at-the-wistar-institute/?sc=rsin /articles/nobel-laureate-drew-weissman-m-d-ph-d-delivers-28th-annual-jonathan-lax-memorial-lecture-at-the-wistar-institute/?sc=rsin Wed, 10 Jul 2024 14:05:35 EST July 16th at 6:30 pm EDT, Nobel Laureate in Medicine or Physiology Drew Weissman, M.D., Ph.D., delivers the 28th annual Jonathan Lax Memorial Lecture at The Wistar Institute in recognition of his outstanding contributions to HIV research. Wistar Institute /articles/revolutionizing-cancer-treatment-wistar-and-accelerated-biosciences-collaborate-to-pioneer-transformative-immune-cell-therapies/?sc=rsin /articles/revolutionizing-cancer-treatment-wistar-and-accelerated-biosciences-collaborate-to-pioneer-transformative-immune-cell-therapies/?sc=rsin Wed, 10 Jul 2024 10:40:58 EST The Wistar Institute is pleased to announce a research collaboration with Accelerated Biosciences Corp. aimed at creating a platform based on human trophoblast stem cells to explore new immunotherapies that use Accelerated Bio's proprietary technology. Wistar Institute /articles/wistar-recruits-jozef-madzo-ph-d-as-director-of-bioinformatics/?sc=rsin /articles/wistar-recruits-jozef-madzo-ph-d-as-director-of-bioinformatics/?sc=rsin Mon, 01 Jul 2024 14:05:09 EST Jozef Madzo, Ph.D., recruited as an assistant professor and director of Bioinformatics, at The Wistar Institute. Wistar Institute