Latest news from Proceedings of the National Academy of Sciences (PNAS) on News en-us Copyright 2024 News 115 31 / /images/newswise-logo-rss.gif /articles/autophagy-in-pdgfr-alpha-mesenchymal-cells-is-essential-for-intestinal-nbsp-stem-cell-nbsp-survival/?sc=rsin /articles/autophagy-in-pdgfr-alpha-mesenchymal-cells-is-essential-for-intestinal-nbsp-stem-cell-nbsp-survival/?sc=rsin Fri, 13 May 2022 05:45:30 EST ... for Atg5, theĀ stemĀ cellĀ loss in vivo was more pronounced than in vitro, suggesting that additional cell populations likely depend upon Atg5 function to support ileum health. We first tested whether ATG5-dependent WNT signaling was required forĀ ... Proceedings of the National Academy of Sciences (PNAS) /articles/atr-activity-controls-nbsp-stem-cell-nbsp-quiescence-via-the-cyclin-f-ndash-scf-complex/?sc=rsin /articles/atr-activity-controls-nbsp-stem-cell-nbsp-quiescence-via-the-cyclin-f-ndash-scf-complex/?sc=rsin Mon, 02 May 2022 08:00:22 EST ...Ā StemĀ cellĀ quiescence is regulated by multiple factors including p53, Rb, cyclin-dependent kinase inhibitors, such as p21 and p27, and Notch signaling (5-10). How these pathways may integrate to maintainĀ stemĀ cellĀ ... Dysregulation or loss of quiescenceĀ ... Proceedings of the National Academy of Sciences (PNAS)