Allergic Rhinitis, Asthma, Atopic Dermatitis, Eczema, Eosinophilic Esophagitis, Hives, Immunology, Mast Cells, Skin Disorders, Venom
, MD, PhD, is a sought-after expert in food allergy, eosinophilic gastrointestinal disease, and eczema (atopic dermatitis). As Chief of the Allergy Program at Children's Hospital of Philadelphia (CHOP), he focuses on improving the quality of life for children with allergies and related conditions.
He is also the Director of the Center for Pediatric Eosinophilic Disorders, Stuart E. Starr Chair of Pediatrics at CHOP and Professor of Pediatrics at the Perelman School of Medicine at the University of Pennsylvania.
Spergel has led multicenter clinical trials for food allergy, EoE, or atopic dermatitis sponsored by NIH, PCORI, industry, foundations, and academic partners. His research identified the role of genetics, foods and t-cells in eosinophilic esophagitis and found that can be outgrown.
Autoimmune, Autoimmune Disease, Cardiac, Heart Failure, Immune Response, Immunology, T-Cell, Vascular Biology
The Alcaide lab at Tufts University School of Medicine combines the areas of immunology, vascular biology, and cardiac physiology to study the adaptive immune response in diverse inflammatory settings, with a particular focus on the heart in the context of heart failure. The over-arching goal of the lab is to better understand the molecular and cellular mechanisms taking place during T lymphocyte trafficking and how those can potentially be targeted in therapeutically useful ways. The Alcaide lab uses several in vivo mouse models of heart failure to study the T cell immune responses involved in cardiac pathophysiology, combined with a broad range of immunological approaches. T cell crosstalk with endothelial cells are studied using in vitro flow systems and real time video microscopy, and they use additional state of the art approaches to investigate the implications of T cell responses on cardiac resident cells.
adaptive immunity, Dna Sequencing, Healthcare, Immunology
I am a Clinical Assistant Professor of Immunology for the Idaho WWAMI Medical Education Program affiliated with the University of Washington School of Medicine. Beyond instructing medical students in Immunology, I maintain an active research lab engaging medical and undergraduate students in clinical and translational research. My lab focuses on infant immune development and the role of the developing immune system in protection from both short and long term morbidities. I have a particular interest in the role of the developing immune system in cognitive development and the role of maternal health in these outcomes.