麻豆传媒

Education and Training:
University of Utah, Salt Lake City, UT	PhD	12/2011	Human Genetics

Awards and Honors:
National Geographic	2018		Explorer Award
American Physiological Society	2017		Giles F. Filley Memorial Award
Francis Family Foundation	2013		Parker B. Francis Fellowship
American Physiological Society	2012		Physiological Genomics Fellowship
University of Utah	2012		James W. Prahl Award, Outstanding PhD in Biomedical Sciences, School of Medicine

Research Interests:
Robert G. Carroll earned his Ph.D. in 1981 under the direction of Dr. David F. Opdyke at the Department of Physiology of the Graduate School of Biomedical Sciences of the University of Medicine and Dentistry of New Jersey-Newark. Following a 3 year post-doc at University of Mississippi Medical Center in Jackson, MS under the sponsorship of Drs. Thomas E. Lohmeier and Arthur C. Guyton, he moved to East Carolina University in 1984 as an Assistant Professor of Physiology. He is currently Professor of Physiology at the Brody School of Medicine at East Carolina University, and holds an administrative appointment as Associate Dean for Medical Student Education.

Back when he did the actual experiments, Rob鈥檚 dissertation examined blood pressure regulation in sharks. His postdoctoral work expanded his interests to cardio-renal integration, which remained a theme for 30 years. He has a passion for education, and now his scholarship focuses on the teaching and learning processes.

Rob currently chairs the Education Committee of the International Union of Physiological Sciences and served the American Physiological Society in a variety of roles, chairing the Education Committee and the Teaching Section and editing the journal 鈥淎dvances in Physiology Education鈥�. He also served on the USMLE Step I Physiology Test Material Development Committee of the National Board of Medical Examiners, and as Secretary for the International Association of Medical Science Educators. In 2002, he was recognized in the inaugural class of Master Educators at the Brody School of Medicine, and as the Arthur C. Guyton Physiology Educator of the Year from the American Physiological Society in 2004. He received the Outstanding Alumni Award from the University of Medicine and Dentistry of New Jersey in 2005, was recognized as a Master Teacher by the International Association of Medical Science Educators in 2013 and the Robert J. Glaser Distinguished Teacher Award from the Association of American Medical Colleges in 2018. His three children, and now three grandchildren, still question his sanity and judgment.

Education/Employment:
B.S. (1976), University of Notre Dame, Notre Dame, Indiana
Ph.D. Physiology (1981), College of Medicine and Dentistry of New Jersey, Newark, NJ
University of Mississippi Medical Center, Jackson, Mississippi
Postgraduate Training (1981-1984)
Instructor (1981-1984)
East Carolina University School of Medicine, Greenville, NC
Assistant Professor of Physiology (1984-1990)
Associate Professor of Physiology (1990-1996)
Professor of Physiology (1996-date)
Interim Chair, Department of Comparative Medicine (2005-2006)
Assistant Dean for Academic Affairs in the Basic Sciences (2011-2015)
Associate Dean for Medical Student Education (2015-date)

Postdoctoral Training
NIH Postdoctoral Fellowship: University of Arizona (Tucson, AZ)

Fellowship and Affiliations
鈥� Virtual Soldier Research Program (UI Center for Computer-Aided Design, College of Engineering; http://www.ccad.uiowa.edu/vsr/)

鈥� Free Radical & Radiation Biology Program (UI Department of Radiation Oncology, Carver College of Medicine; http://frrbp.medicine.uiowa.edu/)

鈥� Fellow, American Physiological Society (Inaugural Class)

Courses Taught
鈥� 027:130 Human Physiology
鈥� 027:141 Exercise Physiology
鈥� 027:148 Physiology of Aging
鈥� 027:241 Integrative Physiology Seminar
鈥� 050:240 Mechanisms of Human Disease (Carver College of Medicine)

Educational/Research Interests
1. Elucidation of cardiovascular, thermoregulatory, and metabolic mechanisms by which an organism copes with various stresses (e.g., exercise, heat, hypoxia).

2. Factors impacting the changes in stress tolerance (e.g., stress proteins, oxidative stress, metabolic dysfunction) aging, diseased, and healthy young systems.

3. Integration of human physiological testing with physics-based digital human modeling and simulation tools for the development of predictive models for enhanced performance and injury prevention.

Professional Activities
鈥� Collegiate Fellow, College of Liberal Arts & Sciences, University of Iowa

鈥� Associate Editor, Journal of Applied Physiology (http://jap.physiology.org)

鈥� Chair, Animals in Research and Education Subcommittee, FASEB Science Policy Committee (http://www.the-aps.org/mm/hp/Audiences/APS-Committees/sciencepolicy)

鈥� Chair, Science Policy Committee, American Physiological Society (http://www.faseb.org/Policy-and-Government-Affairs/Science-Policy-Issues...)

鈥� Board of Trustees, AAALAC (Association for the Assessment and Accreditation of Laboratory Animal Care, International; http://www.aaalac.org)

Research Summary:
Professor Yates鈥� research focuses on the role of the vestibular system in the maintenance of homeostasis, the function of the vestibular system in spatial cognition, and plasticity within the vestibular system following damage to the inner ear. Vestibular receptors detect linear and angular acceleration imposed on the head, and thus provide signals to the central nervous system (CNS) that indicate head position and the direction and velocity of head movements. By integrating vestibular inputs with signals from receptors in the neck, trunk, and limbs, the central nervous system can differentiate head and whole-body movements and thus produce appropriate compensatory responses. Vestibular effects on respiratory motoneurons, on sympathetic neurons that regulate circulation, and on CNS neurons that mediate spatial cognition are the major concern of the laboratory. We are also interested in the mechanisms responsible for recovery of function following loss of vestibular inputs. 

The majority of the current research utilizes electrophysiological and neuroanatomical approaches to characterize the neuronal circuitry that relays vestibular signals to spinal motoneurons, sympathetic preganglionic neurons, and CNS regions that mediate spatial cognition. Furthermore, we are examining the effects of stimulation or lesioning the vestibular system on respiration and circulation, to gain a better understanding of the role of the vestibular system in maintaining homeostasis during movement, changes in posture, and exposure to unusual gravitational environments (such as during space travel). Other experiments are exploring the role of the vestibular system in spatial cognition as well as 鈥渟ensory substitution鈥� that explains recovery of function following vestibular system lesions. Finally, we are interested in the physiological basis of an aberrant autonomic effect that can result from vestibular stimulation: motion sickness.

Education & Training
Ph.D. University of Florida (1986)

Douglas C. Everett, PhD, is a researcher at National Jewish Health. Dr. Everett is in the Division of Biostatistics and Bioinformatics.

Education
1989	SUNY- Buffalo, PhD, Physiology
1983	Duke University, MS, Physical Therapy
1978	Cornell University, BA

Awards & Recognition
2006-Present: Associate Editor, Advances in Physiology Education
2001-Present: Editorial Review Board, Journal of Allergy and Clinical Immunology
2001-Present: Who's Who in America
2001-Present: International Directory of Distinguished Leadership
2001-2006: Editorial Review Board, Advances in Physiology Education
2002-2004: Cochair, Data and Safety Monitoring Committee, National Jewish Health

Professional Memberships
American Physiological Society
International Society on Oxygen Transport to Tissues
New York Academy of Sciences
American Statistical Association
International Society for Mountain Medicine

Assistant Professor
Clinical Assistant Professor
Assistant Scientist
Assistant Scientist
Director, Leukemia Molecular Epidemiological Resource Core
Clinical Assistant Professor
Assistant Professor of Health and Human Physiology
Assistant Professor of Internal Medicine - Hematology, Oncology and Blood and Marrow Transplantation

Education
BS, Biology, University of California
PhD, Philosophy, Physiology, The Pennsylvania State University
Postdoctoral Fellow, Department of Pediatrics, The University of Wisconsin

The long-term goal of our research program is to elucidate mechanisms of obesity-associated coronary microvascular dysfunction and thereby identify novel pathways and therapeutic targets to reduce cardiovascular complications in these patients. The central premise of our work is that coronary microvascular dysfunction and the resultant impairment of coronary blood flow control is an independent predictor of cardiovascular morbidity and mortality in obese, diabetic patients. Impaired coronary microvascular function is estimated to account for more than 60% of cardiac perfusion defects in patients with type 2 diabetes. Thus, coronary microvascular dysfunction is a significant contributor to impaired cardiac function, ischemia, infarct, and mortality in these patients.

Current projects in the laboratory focus on the role of the aldosterone-binding mineralocorticoid receptor (MR) as a mediator of coronary and cardiac dysfunction in obesity. A growing body of evidence has implicated MR signaling in vascular cells as an important mediator of vascular and cardiac dysfunction in various disease states. Our studies utilize an integrative combination of in vivo and in vitro approaches including cell/tissue culture and clinically relevant mouse models coupled with molecular techniques.

Bio:
Born Hanover, NH, B.A. Chemistry Duke University 1972, PhD Physiology, University of Minnesota 1981, postdoc Pulmonary Medicine, UCLA 1980-1986, faculty USD School of Medicine 1986-present

Teaching Interests:
physiology (both basic and advanced), introductory biology for future elementary teachers, biomedical ethics, teaching fundamentals for graduate students, membrane transport, nerve and muscle physiology, XDIS, FYE

Research Interests:
how to improve student learning using innovative and active pedagogy, review articles of scientific concepts for the lay public

Education:
Ph D, physiology, University of Minnesota, 1981
BA, chemistry, Duke University, 1972
Grants:
SD BRIN Bridge Funding, National Institutes of Health. (2014 - 2015)
SPURA - Summer Program for Undergraduate Research in Addiction, NIH/NIDA. Grant Role: Co-Principal. (2013 - 2018)
SPURA - Summer Program for Undergraduate Research in Addiction, NIH/NIDA. Grant Role: Co-Principal. (2013 - 2018)
RCN-UBE Incubator: Growing a Physiology Education Community of Practice, National Science Foundation. Grant Role: Co-Principal. (2013 - 2014)
South Dakota Science and Mathematics Teacher Enhancement: Integrating Math and Science and Using Topical Issues in Science Instruction, SD Board of Regents and US Dept of Education. Grant Role: Co-Principal. (2011 - 2012)
Science and Mathematics Instruction In Context for South Dakota in the 21st Century, SD Board of Regents and US Dept of Education. Grant Role: Co-Principal. (2010 - 2011)
Supplement to SD BRIN for undergraduate and high school researchers, NIH. (2009 - 2010)
SD Biomedical Research Infrastructure Network Supplemental, NIH. Grant Role: Principal. (2001 - 2014)
IDeA Networks of Biomedical Research Excellence, NIH. Grant Role: Principal.
RCN-UBE Incubator: Growing a Physiology Education Community of Practice, National Science Foundation.

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Frans H.H. Leenen received his PhD and MD from the University of Utrecht, The Netherlands.  He completed his residencies in internal medicine and cardiology at the University of Utrecht Medical School and teaching hospitals.  He obtained postdoctoral research training at the University of Utrecht and the University of Pittsburgh.  Dr. Leenen is currently Professor of Medicine and Pharmacology at the University of Ottawa School of Medicine, and Director of the Hypertension Unit at the University of Ottawa Heart Institute.

Recent Publications

Huang BS, Leenen FHH. The brain renin-angiotensin-aldosterone system: a major mechanism for sympathetic hyperactivity and LV remodeling and dysfunction post MI. Current Heart Failure Reports 6:81-88, 2009.
Leenen FHH.  The central role of the brain aldosterone-鈥渙uabain鈥� pathway in salt sensitive hypertension.  Biochimica et Biophysica Acta, Special Issue 鈥淢olecular Basis of Disease Arterial Hypertension鈥�  1082:1132-1139, 2010.
Leenen FHH, McInnis MH, Fodor G.  Obesity and the Prevalence and Management of Hypertension in Ontario.  American Journal of Hypertension 23:1000-1006, 2010.
Leenen FHH, Schiffrin EL.  Control rates of Hypertension in North America.  Editorial Commentary, Hypertension 56:571-572, 2010.
Huang BS, Ahmadi S, Ahmad M, White RA, Leenen FHH.  Central neuronal activation and pressor responses induced by circulating ANG II:  Role of brain aldosterone-鈥渙uabain鈥� pathway.  American Journal of Physiology  299:H422-H430, 2010
McAlister FA, Wilkins K, Joffres M, Leenen FHH, Fodor G, Gee M, Tremblay MS, Walker R. Johansen H, Campbell N.  Changes in hypertension awareness, treatment, and control rates in Canada over the past two decades.  Canadian Medical Association Journal, 183:1007-1013, 2011.
Present Research Group

Research Associates

Monir Ahmad, MD
Hong-Wei Wang, MD PhD
Bing Huang, MD, PhD

Education: PhD 1999, Baylor College of Medicine
Specialty: cardiovascular sciences
Major interest: myocardial infarction-induced cardiac wound healing
Affiliations: Dean, School of Graduate Studies, Meharry Medical College; Research Biologist, Nashville VA Medical Center; Editor-in-Chief, American Journal of Physiology-Heart and Circulatory Physiology
Citations: 13,470; h-index: 62
Research interests: extracellular matrix, cardiac remodeling, aging, inflammation, fibrosis

Professor in the Kinesiology department at Pennsylvania State University

Education
Penn State University
Penn State University
Degree NameDoctor of Philosophy (PhD)Field Of StudyVascular Aging and Exercise
Dates attended or expected graduation2015 鈥� 2019

Audrey A. Vasauskas, PhD, serves as Director of Research & Grant Development and Associate Professor of Physiology. Dr. Vasauskas obtained her Bachelor of Science in biology from Mount Saint Mary鈥檚 University in Maryland. She earned her PhD and completed post-doctoral training from the University of South Alabama College of Medicine. Dr. Vasauskas has been the recipient of several extramural research grants from the National Institutes of Health and the American Heart Association. She has also served as a science policy and research advocate to the United States Congress. Dr. Vasauskas has been teaching cell and system physiology for over a decade and has mentored many undergraduate, graduate and medical students both in academia and industry. Prior to her career in academia, she spent several years in the biotechnology industry as project leader for oncology diagnostic development. During her time at ACOM, she has served as Research Committee chair and principal investigator. Dr. Vasauskas鈥檚 current research includes the molecular changes that occur within endothelial cells in the pathology known as pulmonary arterial hypertension. Specifically, her NIH-funded research investigates potential players in endothelial to mesenchymal transition, or the process by which endothelial cells transition to a smooth muscle, constrictive phenotype.

About
I am an Instructor of Anatomy and Physiology and Pathophysiology. I enjoy communicating science to diverse audiences.

I believe in creating equal access and opportunity for everyone interested in STEM. I am involved in the efforts of my College's Inclusion and Diversity committee and am Chair of the Diversity and Inclusion Committee for the American Physiological Society.

Specialties: physiology, pathophysiology, science communication 

Dr. Tim Musch, Professor in Kinesiology, was named a University Distinguished Professor. He was also chosen for the 2018 Environmental and Exercise Physiology Honor Award from the American Physiologic Society. This award recognizes previous or current primary member of the EEP Section who has made significant research contributions to the scientific advancement of environmental, exercise, thermal, or applied physiology while making significant contributions to enhancing the objectives of the Section.

Research Interests:
Coronary heart disease
Chronic heart failure

Education:
PhD., 1991. Zoology. University of British Columbia
M.S., 1985. Biology. Portland State University
B.S., 1980. Biology. Lewis and Clark College

Research Physiologist Tactical Combat Casualty Care Research, U.S. Army Institute of Surgical Research

Dr. Carmen Hinojosa-Laborde is a native of San Antonio, TX. After postdoctoral training in Wisconsin and Iowa, Dr. Hinojosa-Laborde and her husband returned to San Antonio to raise their two children. She joined the Research Faculty at The University of Texas Health Science Center San Antonio in 1992. During her academic career, her research focused on sex differences in blood pressure regulation with an emphasis on hypertension and aging.

After 17 years at UT Health San Antonio, Dr. Hinojosa-Laborde was recruited to join the scientific community at the U.S. Army Institute of Surgical Research (USAISR) in 2009. As a government scientist, Dr. Hinojosa-Laborde鈥檚 current research focuses on the pathophysiology of hemorrhage.

Career path
Dr. Hinojosa-Laborde was recruited to the U.S. Army Institute of Surgical Research because of her experience as an integrative scientist. While the environment in a government lab was very different from academia, Dr. Hinojosa-Laborde was excited about the opportunity to re-direct the focus of her research to support the military effort to care for the combat wounded. Since joining the U.S. Army Institute of Surgical Research, Dr. Hinojosa-Laborde has experienced a great sense of satisfaction in her research and honor in the knowledge that she is contributing to the health care of U.S military members.

Opportunities
Dr. Hinojosa-Laborde is willing to interact with students to discuss opportunities in U.S. Military Research and discuss differences between academic and government research laboratories.

Adjunct Professor, Kinesiology and Integrative Physiology
Affiliated Professor, Biological Sciences, Cognitive and Learning Sciences
PhD, Biological Sciences, Michigan Technological University
BS, Biological Sciences, Michigan Technological University

Research Interests
Autonomic and Cardiovascular Control in Humans
Neurovascular Responses to Mental Stress
Sleep and Autonomic Activity in Humans
Sex Differences and Sympathetic Activity
Aerobic and Anaerobic Balance in Elite Athletes

Gisele A Oda received her B.S., M.S. and Ph.D degrees in Physics from the University of S茫o Paulo in 1990, 1992 and 1998, respectively. From 1999 to 2000, she was a posdoc in the Center for Biological Timing, University of Virginia. From 2001 to 2006, she was a posdoc in Physics at the University of S茫o Paulo. She is currently an Assistant Professor at the Department of Physiology at the Institute of Biosciences, University of S茫o Paulo. Her research interests include: Chronobiology, Comparative Physiology, Nonlinear Dynamics.

Work in my research laboratory focuses on examining physiological, biochemical and molecular mechanisms by which animals respond to environmental change. The fundamental questions we ask are: Why do organisms live where they live, and how do they do so? What causes populations to remain stable, grow, fluctuate in size, or go extinct? How does the physical environment, the presence predators, the genetic properties of a population and the abilities of individuals to adapt to the environment all influence their distribution and abundance? As ecosystems experience rapid climate change, it is imperative to understand and address these questions in vulnerable natural populations.

The primary study system in which we explore these questions are populations of the native willow beetle Chrysomela aeneicollis, which experiences extreme climatic conditions in the Sierra Nevada Mountains of California. We are characterizing Sierra beetle populations using molecular markers of genetic variation and environmental adaptation. We are also assessing changes in population size and distribution using these genetic markers, and linking changes to local topography and to climate, which we assess using locally deployed loggers and weather stations. Because we have been studying these populations for over 20 years, we are able to include historical samples from populations that are now extinct in our analysis, which offers us the rare opportunity to analyze changes in populations for which the past environment is characterized. We are also conducting experiments to quantify fecundity, larval survival, and adult over-wintering survival to assess potential mechanisms contributing to population persistence for beetles of differing genetic and environmental backgrounds. 

We also study the adaptive significance of color polymorphisms in coastal populations of leaf beetles. In California, temperatures in the coastal region vary greatly over relatively short spatial scales, with cool, moderate conditions prevailing along the coast and inland valleys, and warm conditions with greatly fluctuating temperatures prevailing inland and along the tops of ridges in coastal mountain ranges. California populations of the leaf beetle Chrysomela schaefferi occurs along the California coast and in the coastal mountains. Melanic (darkly-pigmented) and light-colored forms are found in this beetle species. Melanic individuals are deep brown, non-melanics copper colored. Melanics are found in higher frequency in cooler habitats than further inland, where maximum temperatures are much greater. Some authors propose that melanism represents an adaptation to temperature in other insect systems, but few have investigated physiological mechanisms supporting the thermal melanism hypothesis. We are studying temperature adaptation in this beetle, focusing on how changes in temperature interact with color pattern and genetic variation to affect factors altering performance and reproductive success: heat shock protein expression, running speed, fecundity and mating frequency. 

The heart of this research program are the efforts of undergraduates, who work intensively in the laboratory and field as a collaborative, interdisciplinary team. Team Beetle. This research is currently funded by the National Science Foundation, a Clare Booth Luce Fellowship, an SCU undergraduate research grant, and a Fulbright Scholarship.

Education

B. A. Chemistry and Biology, University of California Santa Cruz

Ph. D. Marine Biology, Scripps Institution of Oceanography, UC San Diego


Andrew Mellon Postdoctoral Fellow, Marine Ecology, Oregon State University