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Scientists at the Whitehead Institute for Biomedical Research and Genetics Institute, Inc. have identified a new gene called derriere that plays a key role in the development of the frog embryo from the neck down, including the neural tube and the muscles flanking the spinal cord.
Genetic studies at the Whitehead Institute for Biomedical Research have shown that some boys will be infertile as adults because they have inherited a genetic defect from their fathers through a commonly used method of assisted reproduction known as intracytoplasmic sperm injection.
Researchers led by Dr. Robert A. Weinberg of the Whitehead Institute for Biomedical Research have made the first genetically defined human cancer cells, according to a report published in the July 29 issue of Nature. This achievement brings scientists one step closer to understanding the complex process by which human cells become cancerous.
Whitehead Institute scientists have achieved a major step toward finding a new class of oral drugs to treat HIV infection. They have identified a class of compounds that prevent HIV infection by stopping the virus at its port of entry into the cell.
New research at the Whitehead Institute sheds light on how sex chromosomes evolved from an ordinary pair of autosomes. In a study published in Friday's Science, scientists report that they have reconstructed the stages of sex chromosome evolution and the time course over which these chromosomes were built.
Scientists have found a way to turn a fruit fly into a surrogate mosquito, able to carry malaria and infect chickens with the deadly disease. Their approach may pave the way for better anti-malarial, transmission-blocking vaccines, and engineered mosquitoes that are resistant to malaria (Science, 6-30-00).
Researchers from the Whitehead Institute and the University of Hawaii provide the first molecular evidence for the egg's ability to reprogram an adult cell back to its embryonic state showing X-inactivation in clones is similar to normal development. (Science, 11-24-00)
Researchers at Whitehead Institute and Corning Inc. have invented a powerful new microarray technique that can decipher the function of master switches in a cell by identifying the set of genes they control. The technique allows researchers to unravel in a week what takes years to achieve by conventional methods. (Science, 12-22-00)
In a promising advance in the war against AIDS, scientists have designed a potent, new protein that can prevent HIV infection by blocking its entry into human cells. The protein could therefore serve as the basis for a new class of broad-spectrum, injectible drugs against HIV. (ScienceExpress, 1-11-01)
A florid fungus can be a dangerous beauty, able to coat medical implants with thin films causing complications and even death in patients with medical implants. Researchers have found a gene that allows fungi to stick to plastic surfaces and form thin coatings called biofilms. (Science, 2-2-01)
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