News — The includes a Contemporary Review that discusses what is currently known about how AHR-signaling influences macrophage differentiation, polarization, and function. The issue also features an In-Depth Review that focuses on allergic reactions induced by systemically administered low-molecular weight drugs with an emphasis on drug- and patient-specific factors that could influence the development of drug hypersensitivity reactions. Additionally, a ToxSpotlight article describes a parameter grouping approach when using physiologically based kinetic models while another Tox Spotlight article explores how neonatal BDE-99 exposure may reprogram cell type–specific gene expression and cell-cell communication in the liver.

  • Contemporary Review: “” (free to read)
  • In-Depth Review: “” (open access)
  • ToxSpotlight Article: “” (open access; topic category: biotransformation, toxicokinetics, and pharmacokinetics)
  • ToxSpotlight Article: “” (free to read; topic category: environmental toxicology)

Other papers in the July 2024 issue (sorted by topic category) are:

Clinical and Translational Toxicology
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Developmental and Reproductive Toxicology
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“” (open access)

Emerging Technologies, Methods, and Models
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Endocrine Toxicology
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Exposure Sciences
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Immunotoxicology
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Molecular, Biochemical, and Systems Toxicology
“” (open access)

“” (open access)

Neurotoxicology
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, as well as all past issues, is available on the .

About Toxicological Sciences 
The mission of Toxicological Sciences, the official journal of the Society of Toxicology, is to publish a broad spectrum of impactful research in the field of toxicology. The journal’s primary focus is on original research articles, but it also provides expert insight via contemporary, in-depth, and systematic reviews, as well as forum articles and editorial content that addresses important topics in the field.

About the Society of Toxicology (SOT) 
Founded in 1961,  is a professional and scholarly organization of scientists from academic institutions, government, and industry representing the great variety of scientists who practice toxicology around the world. The Society’s mission is to create a safer and healthier world by advancing the science and increasing the impact of toxicology.