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A groundbreaking study published in Supramolecular Materials introduces a novel supramolecular solution of bakuchiol, a plant-derived retinol alternative, using an ionic liquid (IL) carrier. This innovation achieves a breakthrough in anti-aging by delivering both high efficacy and skin-friendly gentleness.

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Below are summaries of recent Fred Hutch Cancer Center research findings, patient stories and other news.

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With state funding, Washington Sea Grant will work with the Washington Department of Fish and Wildlife and the Woods Hole Oceanographic Institution to shed light on a highly invasive species

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A recent study showcases the power of CRISPR gene editing to significantly boost the production of resveratrol, a plant-derived compound with numerous health benefits. Researchers successfully targeted a key gene in grape cells, redirecting the plant鈥檚 metabolic pathways to prioritize resveratrol production. As a result, engineered grape cells produced over four times more resveratrol than normal, providing a potential solution to the challenges of sourcing this valuable molecule. This innovative method could revolutionize the availability of resveratrol for use in supplements, medicines, and functional foods, and could also serve as a model for increasing the production of other beneficial plant compounds.

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The research team led by Dr. Hyunwoo Kim and Dr. Myungae Bae at the Korea Research Institute of Chemical Technology (KRICT) has developed the nano-probe-based quantitative stiffness measurement technique for a non-alcoholic fatty liver disease (NAFLD) simulate artificial organoid model while minimizing tissue damage.

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Van Andel Institute鈥檚 Hui Shen, Ph.D., has been elected to the American Institute for Medical and Biological Engineering (AIMBE) College of Fellows, a prestigious appointment that represents the top 2% of medical and biological engineers.

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Brian Brown, PhD, Director of the Icahn Genomics Institute at the Icahn School of Medicine at Mount Sinai, has been elected to the College of Fellows of the American Institute for Medical and Biological Engineering (AIMBE).

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By analyzing DNA and proteins in the blood of people with and without acute spinal cord injuries (SCIs), researchers at the Johns Hopkins University School of Medicine have developed a novel blood test that has the potential to rapidly predict severity and likelihood of sensory and motor recovery within six months in a cost-effective manner.

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Scientists have unveiled a revolutionary method for mass-producing high-quality human mitochondria, potentially transforming treatments for degenerative diseases. By refining stem cell culture conditions, researchers achieved an extraordinary 854-fold increase in mitochondrial production while significantly enhancing energy output.

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A new 3D printed customizable hydrogel performed well in preclinical trials with several different types of meniscal tears

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A study led by Johns Hopkins Medicine researchers could advance the development of new drugs that block or open such signaling channels to treat conditions as varied as epilepsy and some intellectual disorders.

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FAMU-FSU College of Engineering researchers have created a new method for studying protein degradation within immune cells that uses engineered microparticles to track and analyze degradation processes more effectively than traditional methods. The work, which was published in ACS Applied Materials & Interfaces, has important implications for treating diseases such as cancer, Alzheimer鈥檚 disease and autoimmune disorders.

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The University of Texas MD Anderson Cancer Center鈥檚 Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson鈥檚 world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.

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This study achieved CRISPR/Cas9-mediated genome editing in grass carp (Ctenopharyngodon idella), China's most economically vital freshwater fish. Targeting the tyrb gene critical for pigmentation were performed. Mutations confirmed by sequencing caused a golden phenotype with melanophore reduction. Using multiple gRNAs enhanced mutation rates (88.9%) and triggered large DNA deletions.

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Engenheiros de manufatura est茫o na vanguarda de trazer novos medicamentos derivados de fontes humanas, como c茅lulas, sangue e genes, para os pacientes. Eles produzem o que muitas vezes s茫o bioterapias pioneiras do seu tipo para doen莽as que anteriormente tinham poucas ou nenhuma op莽茫o de tratamento.

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Manufacturing engineers are at the forefront of bringing new medicines derived from human sources such as cells, blood and genes to patients. They produce what are often first-of-their kind biotherapies for diseases that previously had few or no treatment options.

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JACKSONVILLE, Florida 鈥� Ingenieros de manufactura est谩n a la vanguardia de llevar nuevos medicamentos derivados de fuentes humanas, como c茅lulas, sangre y genes, a los pacientes. Ellos producen lo que a menudo son bioterapias pioneras de su tipo para enfermedades que anteriormente ten铆an pocas o ninguna opci贸n de tratamiento.