麻豆传媒

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A recent study has unveiled a new mechanism driving hepatocellular carcinoma (HCC) progression through the acetylation of pyruvate dehydrogenase complex (PDC) component X (PDHX), a critical component of the PDC. This modification disrupts PDC assembly, inhibits its function, and shifts metabolism towards aerobic glycolysis, promoting tumor growth. The findings highlight PDHX acetylation as both a potential biomarker and therapeutic target, offering new possibilities for liver cancer treatment and advancing our understanding of cancer cell metabolism.

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People with obstructive sleep apnea have an increased risk of Parkinson鈥檚 disease, but if started early enough, continuous positive airway pressure (CPAP) may reduce that risk, according to a preliminary study released today, March 2, 2025, that will be presented at the American Academy of Neurology鈥檚 77th Annual Meeting taking place April 5鈥�9, 2025, in San Diego and online. The study found using CPAP within two years of a sleep apnea diagnosis reduced the risk of Parkinson鈥檚.

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It鈥檚 the multi-million-dollar sports complex, 15 years in the planning and two years to build, but today the UniSA Sport Science Hub opens its doors to its first cohort of university students ready to engage in its world-class teaching and research facilities at South Australia鈥檚 new sports precinct.

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New research, led by Johns Hopkins Children鈥檚 Center investigators and sponsored by the National Institutes of Health鈥檚 (NIH) National Institute of Allergy and Infectious Diseases (NIAID), finds that omalizumab, a U.S. Food and Drug Administration-approved (FDA) injectable drug for food allergies, performed better than oral immunotherapy. A subsequent phase of the study also found that patients may be able to introduce allergenic foods into their diets after stopping the medicine.

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Professor De Wet Swanepoel of the Department of Speech-Language Pathology and Audiology at the University of Pretoria (UP) has received the International Award for Hearing from the American Academy of Audiology. Prof Swanepoel 鈥� who co-founded the hearX Group, a digital health company 鈥� received the award for his research that seeks to expand mobile hearing care to underserved areas locally and globally.

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Productivity Tips from Astronauts

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Finding Meaning in Work

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David M. Dines, MD, a sports medicine surgeon at Hospital for Special Surgery and HSS Long Island, received the Lifetime Achievement Award from Long Island Business 麻豆传媒 at the publication's Health Care Heroes Awards ceremony on February 28.

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Zoom Fatigue

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How Hassles Lead to Turnover

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Ochsner Health is proud to announce a groundbreaking milestone this month. 50,000 minimally invasive robot-assisted surgeries have been performed across the system.

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Experience Doesn't Predict Success

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The kidneys are two bean-shaped organs located just below the rib cage, one on each side of your spine. Healthy kidneys filter blood to remove waste and extra water to make urine. Kidney cancer, also known as renal cell carcinoma or RCC, forms when healthy cells in one or both kidneys grow out of control. March is Kidney Cancer Awareness Month. Learn more with Dr. Saum Ghodoussipour from Rutgers Cancer Institute and RWJBarnabas Health!

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An expanding initiative between Newark and the Rutgers New Jersey Medical School is bringing health care 鈥� and hope 鈥� to the city鈥檚 unhoused population

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Why retinoic acid is effective in this setting but not against primary tumors, has been speculated about for nearly 50 years. St. Jude Children鈥檚 Research Hospital scientists resolved the mystery, showing the drug 鈥渉ijacks鈥� a normal developmental pathway to trigger cancer cell death.

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A University of Illinois Urbana-Champaign research team has developed organic-material-based nanozymes that are non-toxic, environmentally friendly, and cost effective. In two new studies, they introduce next-generation organic nanozymes and explore a point-of-use platform for molecule detection in agricultural products.