Today, the U.S. Department of Energy (DOE) announced $31 million in funding for 42 projects to 36 institutions in 24 states to build research capacity, infrastructure, and expertise at academic institutions across the country. Through the Funding for Accelerated, Inclusive Research (FAIR) initiative, the Office of Science builds strong, long-lasting relationships between lead institutions and DOE National Laboratories, Office of Science scientific user facilities, or research-intensive academic institutions to perform basic research in a broad array of areas, including physics, chemistry, and materials science, that are supported by the Office of Science.
A novel study published today in ADLM’s journal, Clinical Chemistry, has found that it takes the human body much longer than previously thought to clear xylazine — one of the most popular emerging drugs of abuse in the U.S. This much-needed insight into how the body processes xylazine could improve treatment of overdose patients who’ve taken it.
Sobre la base de trabajos anteriores, los investigadores de ACS Infectious Diseases han demostrado un posible tratamiento antibacteriano a partir de una darobactina modificada, un compuesto originario de una bacteria. El equipo informa de pruebas de concepto en animales con infecciones causadas por bacterias, entre ellas, E. coli, conocidas por desarrollar farmacorresistencia.
Chemists have developed a novel way to capture and convert carbon dioxide into methane, suggesting that future gas emissions could be converted into an alternative fuel using electricity from renewable sources.
Building on previous work, researchers in ACS Infectious Diseases have demonstrated a potential antibacterial treatment from a modified darobactin, a compound originally from a bacterium. The team reports proof-of-concept animal trials on infections caused by bacteria, including E. coli, that are known to develop drug resistance.
Researchers at the Beckman Institute for Advanced Science and Technology at the University of Illinois Urbana-Champaign discovered a new type of palladium hydride nanoparticle by adding electrons to palladium ions and water molecules.
For the first time, scientists can distinguish the proportion of bromoform molecules that directly break bonds (dissociate) vs. those that rearrange (isomerize). This is an important step toward understanding the formation of bromoform isomers, which had long been predicted but had not been fully experimentally confirmed.
A la mayoría de la gente no le gusta aplicarse vacunas o inyecciones para recibir tratamientos. Por eso, los investigadores trabajan para crear más medicamentos, como los que se fabrican a partir de ARN mensajero (ARNm), que puedan pulverizarse e inhalarse. Un estudio publicado en la revista Journal of the American Chemical Society informa sobre los avances para hacer posible los medicamentos de ARNm inhalables. Los investigadores indican que la nanopartícula de polímero lipídico, que es estable cuando se nebuliza y libera aerosoles (gotitas líquidas) en los pulmones de ratones de forma satisfactoria, se optimizó para contener el ARNm.
Los rayos X son un componente habitual de las pruebas diagnósticas y el monitoreo industrial, y se utilizan para todo, desde el control de los dientes hasta el escaneo de maletas en el aeropuerto. Sin embargo, los rayos de elevada energía también producen radiación ionizante, que puede ser peligrosa tras exposiciones prolongadas o excesivas. Ahora, investigadores que publican en ACS Central Science han avanzado hacia rayos X más seguros con la creación de un detector altamente sensible y plegable que genera imágenes de buena calidad con dosis más pequeñas de estos rayos.
A study in the Journal of the American Chemical Society reports steps toward making inhalable mRNA medicines a possibility. Researchers outline their improved lipid-polymer nanoparticle for holding mRNA that is stable when nebulized and successfully delivers aerosols (liquid droplets) in mice’s lungs.
Few questions have captivated humankind more than the origin of life on Earth. How did the first living cells come to exist? How did these early protocells develop the structural membranes necessary for cells to thrive and assemble into complex organisms? New research from UC San Diego has uncovered a plausible explanation involving the reaction between two simple molecules.
Nearly three dozen Binghamton University, State University of New York researchers have been honored for their work by a Stanford University study that looks at the impact of scientists worldwide. The recently released ranking has identified 33 current faculty who were among the top 2% of all researchers in the world in their fields in 2023.
The behavior of catalysts that promote chemical reactions is not always straightforward. Using a combination of experiments and computer simulations, scientists now understand how oxygen affects the way the catalyst copper oxide reacts with hydrogen versus carbon monoxide gases and how to control and enhance related chemical reactions.
Researchers who previously demonstrated a cooling fabric coating now report on additional tests of a treated polyester fabric in ACS Applied Materials & Interfaces. Fabric treated with the team’s chalk-based coating kept the air underneath up to 6 degrees Fahrenheit cooler in warmer urban environments.
Join Nobel Laureate in Chemistry, Prof. Jean-Marie Lehn, for an inspiring talk on Supramolecular and Adaptive Chemistry! This is a unique chance to hear directly from one of the world’s most distinguished chemists as he explores how Constitutional Dynamic Chemistry (CDC) leads to adaptive, evolving systems of increasing complexity.
En un estudio publicado en la revista ACS Sensors, investigadores informan del desarrollo de sensores ultrasensibles a nanoescala que, en pruebas a pequeña escala, distinguen un cambio clave en la química del aliento de personas con cáncer de pulmón.
Exhaled breath contains chemical clues to what’s going on inside the body, including diseases like lung cancer. And devising ways to sense these compounds could help doctors provide early diagnoses — and improve patients’ prospects. In a study in ACS Sensors, researchers report developing ultrasensitive, nanoscale sensors that in small-scale tests distinguished a key change in the chemistry of the breath of people with lung cancer. November is Lung Cancer Awareness Month.