Using cannabis products during pregnancy may negatively affect offspring lung development and function, according to new research.
A groundbreaking open-source computer program uses artificial intelligence to analyze videos of patients with Parkinson's disease and other movement disorders. The tool, called VisionMD, helps doctors more accurately monitor subtle motor changes, improving patient care and advancing clinical research.
Fast, cost-effective identification of safe protein insertion sites could enable advanced biosensors and multi-functional proteins
Researchers have completed a comprehensive natural history study of SCN8A-related disorders, which represent a spectrum of neurological symptoms. The study, using retrospective clinical information analyzed through novel data analysis methods, revealed a range of seizure types and neurodevelopmental features, and identifies potential targets for future clinical trials.
Innovative technology could help detect early heart disease through synthetic echocardiograms.
Lawrence Livermore National Security, LLC (LLNS), the contract manager for Lawrence Livermore National Laboratory (LLNL), is now accepting applications for its 2025 Community Gift Program.
Most cancer genome studies have focused on mutations in the tumor itself and how such gene variants allow a tumor to grow unchecked. A new study, led by researchers at Washington University School of Medicine in St. Louis, takes a deep dive into inherited cancer mutations measured in a healthy blood sample and reports how those mutations might take a toll on the body鈥檚 cells starting at birth, perhaps predisposing a person to develop cancers at various stages of life.
A new multicenter study by researchers at the Icahn School of Medicine at Mount Sinai, in collaboration with the National Cancer Institute-funded Clinical Proteomic Tumor Analysis Consortium (CPTAC) and colleagues around the world, has discovered that the genes we are born with鈥攌nown as germline genetic variants鈥攑lay a powerful, underappreciated role in how cancer develops and behaves.
When constructing or updating a hydropower facility, operators face a daunting array of turbine technology choices. The wrong decision can lead to costly delays and reduced profits, while choosing the right technology can boost efficiency, cut costs and reduce development timelines.
Scientists developed a new way of investing in stocks using natural language processing. Using dynamic topic modeling, a variant of Latent Dirichlet Allocation, the new model uncovers hidden risk factors directly from company reports and translates them into tradable indices with minimal human oversight.
This study uncovers dynamic immune adaptations during pregnancy through single-cell RNA sequencing of peripheral blood mononuclear cells at different pregnancy stages. A gradual reduction in cytotoxicity of T and NK cells, along with decreased MHC-II and CD40 signaling in T and B cells, suggests weakened adaptive immunity. Meanwhile, upregulated pro-inflammatory genes in monocytes may compensate for this reduction. Late pregnancy shows a transition toward immune activation in dendritic and CD4+ T cells. Notably, we highlight a novel pro-aging effect of pregnancy, which may reverse postpartum. These findings enhance our understanding of pregnancy immunity and its impact on disease risk.
A recent study has uncovered a potential breakthrough in treating osteonecrosis of the femoral head (ONFH), a debilitating bone disease that causes severe pain and joint collapse. Researchers have discovered that exosomes derived from M2 macrophages-derived exosomes (M2-Exos) can significantly improve bone regeneration by modulating neutrophil extracellular traps (NETs) and endothelial cell function. These tiny vesicles, packed with miR-93-5p, were shown to reduce harmful NETs formation and enhance blood vessel growth, offering a novel therapeutic approach. This discovery highlights the potential of M2-Exos to address the root causes of ONFH, paving the way for non-invasive treatments that could prevent bone deterioration and improve patient outcomes.
Sandia National Laboratories is helping defend deployed troops and the nation against hypersonic threats. During a March 24 test, the Missile Defense Agency, in cooperation with the Navy, launched a Sandia-developed hypersonic target.
ProBio, a global leader in the antibody discovery and development, is pleased to announce its upcoming poster presentation at the American Association for Cancer Research鈸� (AACR) 116th Annual Meeting, to be held April 25 to 30, 2025, at the McCormick Place Convention Center in Chicago, Illinois.
Scientists recognized by the Department of Energy (DOE) Office of Science Distinguished Scientist Fellow Award are pursuing answers to science鈥檚 biggest questions.
Wistar and collaborators have discovered a type of 鈥渕olecular glue鈥� that can be used to inhibit certain pathological protein interactions.
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