How ecDNA Fuels Cancer by Breaking the Laws of Biology
Howard Hughes Medical Institute (HHMI)How ecDNA Fuels Cancer by Breaking the Laws of Biology
How ecDNA Fuels Cancer by Breaking the Laws of Biology
Computational protein design and protein structure prediction have earned three scientists the 2024 Nobel Prize in Chemistry.聽David Baker, a Howard Hughes Medical Institute (HHMI) Investigator at the University of Washington School of Medicine, and Demis Hassabis and John M. Jumper of Google DeepMind were announced as this year鈥檚 recipients by the Royal Swedish Academy of Sciences today.
The Royal Swedish Academy of Sciences announced today that HHMI Investigator Carolyn Bertozzi of Stanford University, Morten Meldal of University of Copenhagen, and K. Barry Sharpless of Scripps Research Institute are the recipients of the 2022 Nobel Prize in Chemistry for the development of click chemistry and bioorthogonal chemistry.
Scientists discover how fat triggers a gut-to-brain mechanism that drives us to keep consuming more of it. Their findings could one day lead to interventions to help treat obesity and associated disorders.
Analyzing DNA from the remains of hundreds of ancient humans across West Asia, the Balkans, Greece, present-day Turkey, and other regions, scientists have revealed surprising migrations that illuminate human history and led to the languages billions of people speak today.
Blanton Tolbert, a biochemist and administrative leader of diversity, equity, and inclusion efforts at Case Western Reserve University, will serve as an HHMI vice president and head of the Institute鈥檚 new Center for Science Leadership and Culture.
The Freeman Hrabowski Scholars Program will support up to 150 early career scientists for their research and their efforts to create labs in which everyone can thrive. Applications to the program are open now.
More than two decades of effort went into a project that has now revealed the structure of a crucial signaling molecule, opening the door to new and better drugs for some cancers.
Tiny cellular machines called ribosomes build proteins. When this building process goes awry in bacteria, ribosomes collide, triggering the arrival of a first responder molecule that begins a rescue operation.
Gut bacteria brew all sorts of chemicals, but we don鈥檛 know what most of them do. A new study suggests that one such compound, previously linked to cancer, may serve as a bizarre weapon in microbial skirmishes.
As teams of researchers around the world race to piece together a picture of the Omicron variant, they鈥檙e fast-tracking discoveries and transforming the way science is done.
The scientists come from 21 US institutions and will join a community of Investigators who are tackling some of the most challenging problems in biomedical research.
In a rare gecko color variety known as Lemon Frost, scientists have traced an unusual coloring and tendency to form tumors to a gene linked to human melanoma.
Scientists have identified proteins in aphid saliva that can alter plant development. These proteins drive abnormal growths called galls, which give insects a protected place to feed and reproduce.
HHMI announces the selection of 21 exceptional early career scientists as 2020 Hanna Gray Fellows to support diversity in biomedical research. The 2022 Hanna H. Gray Fellows Program competition will open later this year.
Like a computer, cells must process information from the outside world before they respond. Scientists have now developed a powerful new way to observe the internal discussions responsible for cellular decisions.
People who have recovered from coronavirus can make potent antibodies to SARS-CoV-2 that evolve in the months after infection. These antibodies may be evolving in response to residual viral antigen hidden in the gut.
The Royal Swedish Academy of Sciences announced today that Howard Hughes Medical Institute (HHMI) Investigator Jennifer Doudna of University of California, Berkeley, and Emmanuelle Charpentier of the Max Planck Unit for the Science of Pathogens are the recipients of the 2020 Nobel Prize in Chemistry for the development of a method for genome editing.
Two new studies offer an explanation for why COVID-19 cases can be so variable. A subset of patients has mutations in key immunity genes; other patients have auto-antibodies that target the same components of the immune system. Both circumstances could contribute to severe forms of the disease.
A new analysis of difficult-to-access genetic variation is the most comprehensive ever conducted in plants. It could guide the improvement of tomatoes and other crops.