How the HIV inserts its capsid into the host cell鈥檚 nuclear pore is a puzzle and a therapeutic target. Simulations on the Pittsburgh Supercomputing Center鈥檚 Bridges-2 system by a University of Pittsburgh team revealed how changes in the shape of the HIV-1 capsid protein may help the capsid be more flexible.
In real life, mutants can arise when their DNA changes to give them an advantage over the rest of the population. A team from the University of Michigan has used simulations on the Pittsburgh Supercomputing Center鈥檚 Neocortex system to find out why beneficial mutants rarely come to dominate real organisms.
A team of interns from the Pittsburgh Supercomputing Center has been selected to represent the U.S. next year at a student competition at the International Supercomputing Conference (ISC25) in Hamburg, Germany, in June 2025.
Parkinson鈥檚 research, a genetic commonality among very different species that learn how to vocalize, an AI-based water treatment training simulator, and a national AI collaboration underlie four annual HPCwire Awards won by PSC this year.
A team from the University of Houston found that, when they reduced estimates of atmospheric friction of storms, their predictions on PSC鈥檚 Bridges-2 improved markedly over standard storm predictions. This advancement promises better planning to lessen the effects of storms on people and possibly aid emergency storm responses.
$4.9 million from the NSF has funded an upgrade to PSC鈥檚 flagship Bridges-2 supercomputer. The grant has allowed the center to add late-model powerful NVIDIA H100 GPUs to the system, further enhancing its ability to support research in and requiring artificial intelligence, particularly in the context of massive data and high-performance computing.
A third-generation Anton supercomputer, developed by D. E. Shaw Research, will soon arrive at the Pittsburgh Supercomputing Center. A $3.15-million, five-year award from the National Institutes of Health will fund the system's operations, making it available without cost for non-commercial use by biomedical researchers at U.S. universities and other nonprofit institutions.
A Carnegie Mellon University-led team has used the Pittsburgh Supercomputing Center鈥檚 Bridges-2 system and input from different cultures to develop an effective fine-tuning approach for retraining a popular image generator so that it can generate equitable images for underrepresented cultures.
In a paper in the prestigious journal Science to appear on Feb. 29, 2024, a multi-institutional team led by scientists at Carnegie Mellon University and University of California at Berkeley found parts of the genome, both within genes and outside of them, that evolved and are associated with vocal learning across mammals. These elements have been linked to autism in humans.
PSC鈥檚 Neocortex AI system is among six national AI supercomputers participating in a pilot program to support novel and transformative AI research and education at a national scale.
We鈥檝e learned a lot about the Universe from telescopes that are sensitive to anything from high-energy gamma waves to visible light to low-energy radio waves. But detecting such electromagnetic waves has limitations.
We might think that, if you want to feed more people in areas with food insecurity, you can just grow more food. But it isn鈥檛 that simple.
A set of nine scientific papers was released today in the Nature family of journals and the journal Cell Reports describing breakthroughs in creating an open framework for scientists to map the individual cells of the human body in two and three dimensions.
James Barr von Oehsen has been selected as the director of the Pittsburgh Supercomputing Center (PSC), a joint research center of Carnegie Mellon University and the University of Pittsburgh. Von Oehsen is a leader in the fields of cyberinfrastructure, research computing, advanced networking, data science and information technology.
Cerebras Systems, the pioneer in high performance artificial intelligence (AI) compute, today announced, for the first time ever, the simulation of a high-resolution natural convection workload at near real-time rates.
Tuomas Sandholm鈥檚 work since 2010 to improve the fairness and effectiveness of organ donations using PSC supercomputers has won the 2023 AAAI Award for Artificial Intelligence for the Benefit of Humanity.
A team at Ohio University used the Pittsburgh Supercomputing Center鈥檚 Bridges-2 system to carry out a series of simulations showing how coal might eventually be converted to valuable 鈥� and carbon-neutral 鈥� materials like graphite and carbon nanotubes.
Science performed with the Pittsburgh Supercomputing Center鈥檚 advanced research computers has been recognized with two HPCwire Editors鈥� Choice Awards, presented at the SC22 conference in Dallas, Texas.
Teams at the Pittsburgh Supercomputing Center, University of Pittsburgh and the Carnegie Mellon University School of Computer Science will lead collaborations and provide computing, software and data infrastructure as part of an international network of centers working to create a kind of cell-level Google Maps for the human body.
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