Scientists have long been trying to tease apart hepatitis A virus, to understand its inner workings and how it functions in the human body. Infectious disease researchers at the UNC School of Medicine have discovered that a little-known protein, PDGFA-associated protein 1 (PDAP1), is used as a pawn by hepatitis A virus to replicate and infect cells in the liver.
A comprehensive analysis published in the journal Gastroenterology and led by Michael D. Kappelman, MD, MPH, at the UNC School of Medicine reveals that U.S. pediatric IBD rates have increased, ranking among highest globally.
Recent advances in bladder cancer treatments may offer hope of curative care to more patients, including those with high-risk localized, muscle-invasive disease, according to a New England Journal of Medicine editorial published by Matthew Milowsky, MD, FASCO, a bladder cancer expert at UNC School of Medicine and UNC Lineberger Comprehensive Cancer Center.
A large study co-led by Kori Flower, MD, MS, MPH, division chief of General Pediatrics and Adolescent Medicine at the UNC School of Medicine demonstrates that combining text messaging with in-person clinic counseling reduces obesity in the first two years of life.
A new study led by Jasmine Weiss, MD, MHS, FAAP, assistant professor of pediatrics in the UNC School of Medicine, describes the barriers to medical school admission that students at Historically Black Colleges and Universities (HBCUs) may face. The study was published in JAMA Network Open.
Researchers at the UNC School of Medicine show how sleep loss during early life impacts key aspects of brain development and how it can increase one鈥檚 risk for developing autism spectrum disorder.
Physician scientists at the UNC School of Medicine played a pivotal role in getting this therapy to the bedside, from assisting with clinical trials to the infusion of the first pediatric patient in North Carolina at UNC Children鈥檚.
Publishing in Annals of Allergy, Asthma and Immunology, UNC School of Medicine researchers delve into the perspectives of community and academic providers on the role of biologics and food allergy. This study was led by co-authors Edwin Kim, MD, Division Chief of Pediatric Allergy and Immunology, and Jill Fisher, PhD, professor in the UNC Department of Social Medicine and Center for Bioethics.
A new study by researchers at the UNC School of Medicine has identified a new biological function of 2鈥�3鈥�-cGAMP in the control of cell migration and cancer metastasis. This research also provides further insights into statin drugs that block cell migration.
Researchers at the UNC School of Medicine were awarded $2.3 million from the National Institute of Arthritis, Musculoskeletal and Skin Diseases to study the genetic basis of a chronic skin condition called hidradenitis suppurativa.
The lab of Jason Stein, PhD, associate professor of genetics and member of the UNC Neuroscience Center, has created a controlled model system that could help researchers know more about the genetic variants that increase one鈥檚 risk for developing a psychiatric disorder.
At 7-years-old, Amelia and Makenzie Kahn were diagnosed with juvenile Batten disease, an extremely rare and progressively fatal genetic disorder. Instead of giving in to the disease, the Kahn family searched for a treatment.
With data from extensive genomic surveys of the syphilis bacterium 鈥� correlated with clinical information from patients 鈥� an international team of researchers and doctors are on the hunt for proteins on the surface of the microbe that don鈥檛 vary and could be good targets for a much-needed vaccine
The National Institutes of Mental Health awarded a $2.5-million grant to UNC School of Medicine researchers to study the alarming rise of suicidal behavior in young girls.
UNC School of Medicine researchers are the first to show that an microRNA molecule called miR-29 is instrumental in driving the natural aging process.
For the first time, UNC School of Medicine scientists created and successfully tested a closed-loop system to measure an individual鈥檚 alpha frequencies and stimulate the brain with a low-level alternating electrical current to bring balance to alpha oscillations and alleviate depression symptoms.
Through an analysis of 500+ FDA-authorized AI medical devices, researchers at the UNC School of Medicine have discovered a lack of published clinical validation data for many authorized devices. They also established a standard for medical AI validation.
Jose Rodriguez-Romaguera, PhD, assistant professor at the UNC Neuroscience Center, co-authored a perspective piece in Neuron about the critical role of mentor-mentee relationships, especially for those who come from racially underrepresented groups like himself.
Taghreed Mohammed Al-Turki, PhD, a postdoctoral researcher in the UNC Lineberger lab of Jack Griffith, PhD, describes her long, difficult, and rewarding journey of becoming a telomere scientist as a first-time mother at the University of North Carolina School of Medicine.
A study led by Jeffrey S. A. Stringer, MD, FACOG, professor of obstetrics and gynecology at the UNC School of Medicine, has shown that an AI-enabled, low-cost handheld ultrasound device can estimate gestational age as accurately as expert sonographers, potentially revolutionizing pregnancy care in low-resource settings where healthcare personnel have little ultrasound training.
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