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鶹ý: Researchers’ study show advancements in GP38 contributions to CCHFV and monoclonal antibody therapies
Release date: 8-Apr-2025 1:15 PM EDT
Researchers’ study show advancements in GP38 contributions to CCHFV and monoclonal antibody therapies
U.S. Army Medical Research Institute of Infectious Diseases

A recent study published in Science Translational Medicine involving scientists from the U.S. Army Medical Research Institute of Infectious Diseases in collaboration with scientists from the Albert Einstein College of Medicine and the University of California-Berkeley have advanced discoveries surrounding the viral glycoprotein GP38 expressed by the Crimean-Congo hemorrhagic fever virus (CCHFV).

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Released: 8-Apr-2025 12:00 PM EDT
Powerful New Tool Promises Major Advances in Cancer Treatment
University of South Australia

New Australian technology is set to transform the way that gastrointestinal cancers are detected and treated with precise, minimally invasive surgery.Backed by the Federal Government’s...

鶹ý: Immune Cell Research Identifies Potential New Target for Treating Cancer and Autoimmune Disease
Release date: 8-Apr-2025 12:00 PM EDT
Immune Cell Research Identifies Potential New Target for Treating Cancer and Autoimmune Disease
Johns Hopkins Medicine

In a study of the immune systems of mice, scientists at Johns Hopkins Medicine say they have found a new role for a protein, QRICH1, which could become a target for drugs to dial up or down the activation of T cells to fight cancers and autoimmune diseases.

鶹ý: Desde Chile descubren origen de asteroide que podría impactar a la Luna
Release date: 8-Apr-2025 12:00 PM EDT
Desde Chile descubren origen de asteroide que podría impactar a la Luna
NSF's NOIRLab

Un equipo de astrónomos construyó una representación tridimensional del asteroide 2024 YR4, que fue descubierto recientemente y que se encuentra en las proximidades de la Tierra. Los científicos, además determinaron que el objeto se originó en el cinturón principal de asteroides del Sistema Solar, gracias a las observaciones realizadas desde Chile con el telescopio Gemini Sur, la mitad austral del Observatorio Internacional Gemini de la Fundación Nacional de Ciencias de Estados Unidos y operado por NOIRLab de NSF. Los investigadores también confirmaron que esta roca espacial de forma inusual, es uno de los objetos más grandes de la historia reciente que podría impactar a la Luna.

鶹ý: Gemini South Observes Shape and Origin of Near-Earth Asteroid 2024 YR4
Release date: 8-Apr-2025 12:00 PM EDT
Gemini South Observes Shape and Origin of Near-Earth Asteroid 2024 YR4
NSF's NOIRLab

Using observations from the Gemini South telescope in Chile, one half of the International Gemini Observatory, partly funded by the U.S. National Science Foundation and operated by NSF NOIRLab, astronomers have constructed a 3D representation of the newly discovered near-Earth asteroid 2024 YR4. The team determined that the unusually-shaped rock is one of the largest objects in recent history that could impact the Moon, and that it likely originated from the main asteroid belt.

Release date: 8-Apr-2025 12:00 PM EDT
ACSM Announces Paper of the Year Awards for Scientific Journals
American College of Sports Medicine (ACSM)

The American College of Sports Medicine® annual Paper of the Year selections for each of its six highly acclaimed scientific journals. The awards recognize the demonstrated scientific, scholarly significance and overall impact of an article published during the previous year.

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Release date: 8-Apr-2025 12:00 PM EDT
Chicago Adults Name Gun Violence, Poverty, Lack of Supervision and Social Media as Top Child Health Concerns
Ann and Robert H. Lurie Children's Hospital of Chicago

The report, which gathered perspectives from a diverse group of adults across the city, shows that 79% ranked gun-related violence as a top concern, underscoring the deep impact of community safety on...

鶹ý: Neonatal diabetes model provides insights on how condition develops
Release date: 8-Apr-2025 11:35 AM EDT
Neonatal diabetes model provides insights on how condition develops
UT Southwestern Medical Center

A preclinical model developed at UT Southwestern Medical Center that recapitulates a rare infant-onset form of diabetes suggests the condition stems from gradual damage to the pancreas through misregulation of a molecular pathway called the unfolded protein response (UPR). The findings, published in Molecular Metabolism, could one day lead to new ways to treat more common subsets of diabetes, including Types 1 and 2, which affect hundreds of millions worldwide.

Release date: 8-Apr-2025 11:05 AM EDT
Breakthrough research revolutionizing pulmonary hypertension treatment
Ochsner Health

A recent publication in the International Journal of Cardiology, Pulmonary artery denervation in pulmonary hypertension: A comprehensive meta-analysis, has shed light on the potential of pulmonary artery denervation (PADN) as an innovative intervention for pulmonary hypertension (PH), a condition that places patients at risk for right heart failure and death.

Released: 8-Apr-2025 11:00 AM EDT
Conserved Chromatin Regulators Control the Transcriptional Immune Response to Intracellular Pathogens in Caenorhabditis Elegans
George Washington University

In this study, we show that transcriptional regulators, previously linked to development in Caenorhabditis elegans, also control immune responses. Through forward genetic screens, we found that loss of LIN-15B leads to constitutive activation of Intracellular Pathogen Response (IPR) genes. LIN-15B is functionally associated with the DREAM chromatin remodeling complex, and its loss enhances resistance to intracellular pathogens. This immune response depends on the MES-4 histone methyltransferase. We also discovered that other chromatin regulators, including NuRD and SUMOylation factors, similarly repress IPR gene expression, highlighting a new role in immunity for these conserved regulators of development.


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