Scientists Identify Agent of Transformation In Protein Blobs That Morph From Liquid to Solid
Rutgers University-New BrunswickAn international research collaboration led by Rutgers University-New Brunswick scientists that examined microscopic blobs of protein found in human cells has discovered that some morph from an almost honey-like substance to a hard candy-like solid. These mysterious droplets, known as biomolecular condensates, solidify when they carry a high proportion of the protein alpha-synuclein, the scientists reported in Science Advances. Clumps of alpha-synuclein are commonly found in the brain cells of people with Parkinson鈥檚 disease, a neurodegenerative brain disorder.