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News — NEW YORK, NY – Nov. 12, 2024 – Urgent action is needed, to prevent pneumonia deaths among high-risk groups, particularly children younger than five years and older people, noted the and its Forum of International Respiratory Societies (FIRS) partners.  New effective preventive interventions are available, but these are still inaccessible in many low- and middle-income countries (LMICs).

Professor Heather Zar of the Pan African Thoracic Society executive committee, a FIRS member, said:

“New highly effective interventions to prevent pneumonia in infants and young children have recently become available and can substantially reduce the burden of childhood pneumonia and mortality.  However, access and affordability in LMICs is crucial to reduce global inequity and promote health for all children, especially as most severe illness occurs in LMICs.”

In 2021, including 502,000 (23 percent) children aged less than 5 years and 152,000 (7 percent) newborn babies. The pneumonia burden remains unacceptably high, especially as most deaths are preventable.  In addition, early life pneumonia may lead to poorer health through life and contribute to the development of chronic respiratory disease in adulthood.

1. pneumoniae (pneumococcus) remains one of the most important bacteria causing pneumonia across age groups, while However, there are now effective vaccines for these. Pneumococcal conjugate vaccine, a highly effective vaccine preventing pneumonia from S pneumoniae has been available for over two decades but is still not accessible to many children in poor areas. New, highly effective vaccines against RSV are now available. These include vaccines specifically for older adults, a vaccine for pregnant women, and a long-acting antibody to protect infants and young children. However, there is very limited availability of these in LMICs despite the large number of children developing severe pneumonia in these countries and excellent protection offered by vaccination.

Most deaths occur in the poorest populations in LMICs. Key risk factors for pneumonia include , malnutrition, smoke exposure, HIV infection, and low vaccination rates. For young children, prematurity and lack of breastfeeding are additional risks. Limited access to effective treatment is also a concern, especially in many LMICs, where health care facilities and oxygen systems are often unavailable, particularly for children.

Although pneumonia deaths have substantially declined over the past decade, urgent efforts are still needed to improve access to effective prevention and treatment. On World Pneumonia Day, FIRS is calling on governments and partners to:

• Ensure equitable and sustained access to vaccines against the commonest pathogens.
• Ensure access to new highly effective preventive interventions against RSV for infants and young children globally.
• Strengthen health systems to deliver interventions which reduce pneumonia deaths, including provision of effective vaccines, antibiotics and oxygen delivery systems.
• Strengthen national and international commitment to support interventions against the leading risk factors for pneumonia.
• Improve support for research into cost-effective interventions to prevent and treat pneumonia in LMICs.

The American Thoracic Society is one of seven specialty societies awarded a grant from the Council of Medical Specialty Societies and the CDC to increase COVID-19, influenza and pneumonia vaccination rates among high-risk adult patients in the U.S.  The ATS is partnering with and funding eight health care systems to test and implement strategies to using a Quality Improvement approach. This month the ATS recognizes the for their contributions to the ATS Vaccine Initiative.