麻豆传媒

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Study Provides Scaffold to Selectively Target Drug Breakdown Process

Scientists at St. Jude Children鈥檚 Research Hospital explored selectively blocking the CYP3A4 protein responsible for breaking down large swaths of approved drugs, providing a way to improve drug efficacy.
10-Apr-2025 8:05 PM EDT Add to Favorites

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Chromatin Remodeling Captured in Comprehensive Structural Study

Scientists at St. Jude Children鈥檚 Research Hospital used a series of cryo-EM structures to visualize dynamics pivotal to chromatin remodeling, a process implicated in cancer and developmental disorders.
4-Apr-2025 6:15 PM EDT Add to Favorites

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Preventable Pediatric Cancer Mortality Surges in Areas of Armed Conflict, Exceeding Rates in Non-Conflict Regions

A collaborative research effort in global childhood cancer has revealed the significant negative impact of living in regions of armed conflict on pediatric cancer outcomes.
1-Apr-2025 6:45 PM EDT Add to Favorites

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Removing a Protein 鈥楽ignal Jammer鈥� Improves Immunotherapy

Find how a mitochondrial protein protects cancer cells from immunotherapy, giving scientists a new target type to improve solid tumor treatment & save lives.
19-Mar-2025 7:55 PM EDT Add to Favorites

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Current Antivirals Likely Less Effective Against Severe Infection Caused by Bird Flu Virus in Cows鈥� Milk

Existing antivirals may be less effective against this H5N1 bird flu strain, and prevention measures, such as avoiding raw milk consumption and reducing exposure in dairy workers, may be the most effective way to protect against the virus.
17-Mar-2025 7:45 PM EDT Add to Favorites

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Spotiphy Integrative Analysis Tool Turns Spatial RNA Sequencing Into Imager

Spatial transcriptomics is a cutting-edge technique that characterizes gene expression within sections of tissue, such as heart, skin or liver tissue. Scientists at St. Jude and the University of Wisconsin-Madison today share a generative algorithm...
12-Mar-2025 8:10 PM EDT Add to Favorites

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Repurposed ALS Drug Becomes Imaging Probe to Help Diagnose Neurodegeneration

Scientists at St. Jude Children鈥檚 Research Hospital used positron emission tomography (PET) with edaravone, a drug used to treat ALS, to detect oxidative stress, which leads to brain damage, offering a clear path to detecting neurological...
5-Mar-2025 8:05 PM EST Add to Favorites

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St. Jude Scientists Solve Mystery of How the Drug Retinoic Acid Works to Treat Neuroblastoma

Why retinoic acid is effective in this setting but not against primary tumors, has been speculated about for nearly 50 years. St. Jude Children鈥檚 Research Hospital scientists resolved the mystery, showing the drug 鈥渉ijacks鈥� a normal...
28-Feb-2025 7:15 PM EST Add to Favorites


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St. Jude Appoints Leading Scientist to Create Groundbreaking Center of Excellence for Structural Cell Biology

Georgios Skiniotis, PhD, to develop and lead new center focusing on advanced imaging techniques, including cryo-ET.
21-Nov-2024 3:15 PM EST

World-Renowned St. Jude Virus Experts Now Available for Media Interviews on Vaccine, Viral Ecology & Evolution

19-Aug-2020 4:40 PM EDT

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Maslow鈥檚 Hierarchy of Needs gives us a framework for parenting during a pandemic

The COVID-19 pandemic turned our society on its head. One of the changes was a strange new reality where parents became school teachers overnight.
19-Aug-2020 3:25 PM EDT

Influenza Outlook and Vaccines: Flu Expert and World Health Organization Member available

1-Dec-2017 12:00 PM EST

St. Jude Children鈥檚 Research Hospital Experts at ASCO 2014

31-May-2014 6:00 PM EDT

Annual Report to the Nation on the Status of Cancer: Experts Available to Discuss Pediatric Cancer

18-Dec-2013 5:00 PM EST

Sickle Cell Awareness Month: Experts Available

22-Aug-2013 5:25 PM EDT

Childhood Cancer Awareness Month: Experts Available

22-Aug-2013 5:15 PM EDT

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About

The mission of St. Jude Children鈥檚 Research Hospital is to advance cures, and means of prevention, for pediatric catastrophic diseases through research and treatment. Consistent with the vision of our founder Danny Thomas, no child is denied treatment based on race, religion or a family's ability to pay.

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