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Gene Therapy May Be 鈥淥ne Shot Stop鈥� for Rare Bone Disease

For the last 10 years, the only effective treatment for hypophosphatasia (HPP) has been an enzyme replacement therapy that must be delivered by injection three-to-six times each week. Currently, patients are treated with injections of asfotase alfa,...
3-Feb-2025 9:10 PM EST Add to Favorites

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Leona M. Flores, PhD, Named Vice President of Research Operations at Sanford Burnham Prebys

Leona M. Flores, PhD, has been named vice president of research operations at Sanford Burnham Prebys. She will elevate the research capacity of the institute by working with faculty and other scientists to ensure successful execution of research...
8-Jan-2025 7:20 PM EST Add to Favorites

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Combining Long- and Short-Read Sequencing in Single Cells Reveals New mRNAs in Neurodegenerative Diseases

Researchers led by Jerold Chun MD, PhD, professor in the Degenerative Diseases Program at Sanford Burnham Prebys, published results December 10, 2024, in eNeuro from combining two sequencing technologies in single cells to find new differences in...
19-Dec-2024 8:25 PM EST Add to Favorites

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David D. O鈥橩eefe, PhD, Named Vice President of Research Development at Sanford Burnham Prebys

David D. O鈥橩eefe, PhD, has been named vice president of research development at Sanford Burnham Prebys. His duties will include working with scientists to maximize research funding and increase research capacity at the Institute by nurturing a...
18-Dec-2024 6:45 PM EST Add to Favorites

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Three Sanford Burnham Prebys Faculty Members Ranked Among the World鈥檚 Most Influential Scientists

Three faculty members at Sanford Burnham Prebys are among the most influential scientists worldwide in the 2024 rankings by the Institute for Scientific Information at Clarivate.
6-Dec-2024 2:45 PM EST Add to Favorites

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Controlling Cancer Cells鈥� Gluttony for Glutamine

Researchers at the NCI-Designated Cancer Center at Sanford Burnham Prebys describe two enzymes newly identified for their roles in regulating macropinocytosis, a process cancer cells use to snatch extra nutrients from the jelly-like substance...
5-Dec-2024 4:40 PM EST Add to Favorites

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Decoding and Debugging Biological Programs for a Healthier Future

Alessandro Vasciaveo, PhD, joined Sanford Burnham Prebys as an assistant professor in computational biology and artificial intelligence in fall 2024. He uses his training and experience as a scientist and engineer to advance knowledge of human...
20-Nov-2024 12:10 PM EST Add to Favorites

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Anne Bang Joins $12.7M Research Project on the Genetic Basis of Autism and Schizophrenia

Scientists have linked neuropsychiatric disorders, such as schizophrenia and autism, to changes in many genes involved in early brain development. However, more research is needed to understand how these gene variants influence the biological...
11-Oct-2024 1:05 PM EDT Add to Favorites


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Xueqin Sun seeks to illuminate the underlying causes of cancer

As a new assistant professor at Sanford Burnham Prebys faculty, Sun seeks to better understand the genetic and epigenetic underpinnings of cancers, using genome editing technologies, animal and patient-derived models, and other tools to develop more...
13-Mar-2024 9:05 AM EDT

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Sanjeev Ranade wants to get to the heart of congenital disease

Sanjeev S. Ranade, Ph.D., who joined the faculty of Sanford Burnham Prebys this month as an assistant professor in the Development, Aging and Regeneration program, studies how proteins called transcription factors (TFs) specifically control the...
22-Jan-2024 6:00 AM EST

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When T cells and macrophages talk, Kelly Kersten listens

Kelly Kersten, Ph.D., who joined Sanford Burnham Prebys this month as an assistant professor in the Cancer Metabolism and Microenvironment program, studies the interactions between immune cells and their microenvironment to better understand how...
17-Jan-2024 2:05 PM EST

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Shengjie Feng channels the powers of cryogenic electron microscopy

Shengjie Feng, Ph.D. is an expert in cryo-electron microscopy, a Nobel Prize-winning imaging technology capable of creating stop-action movies of proteins and other biomolecules jostling and connecting with each other while mitochondria and other...
16-Jan-2024 12:05 PM EST

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Fighting Against Triple-Negative Breast Cancer

2-Oct-2017 8:00 AM EDT

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Brrrr...it's WINTER. Can Being Cold Really Help You Burn Calories and Slim Down? An #SBP Researcher Weighs In

31-Jan-2017 2:05 PM EST

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Could Fake Sugar Cause Real Problems with Your Metabolism? An @SBPdiscovery Researcher Wants to Find Out

7-Nov-2016 8:00 AM EST

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To Treat Breast Cancer, Give It a Lifeline

19-Oct-2016 12:05 PM EDT

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About

Sanford Burnham Prebys is an independent biomedical research institute dedicated to understanding human biology and disease and advancing scientific discoveries to improve human health. For over 40 years, our research has produced breakthroughs in cancer, neuroscience, immunology and children鈥檚 diseases, and is anchored by our NCI-designated cancer center and advanced drug discovery capabilities. For more information, visit us at SBPdiscovery.org or on Facebook at facebook.com/SBPdiscovery and on Twitter @SBPdiscovery.

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