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S. Louis Bridges Jr, MD, PhD

Physician-in-Chief and Chair of the Department of Medicine - Chief of the Division of Rheumatology

Hospital for Special Surgery

Autoantibodies, Autoimmune Diseases, Machine Learning, Rheumatic Diseases, Rheumatoid Arthritis, Rheumatology

Dr. Bridges is Physician-in-Chief and Chair of the Department of Medicine at Hospital for Special Surgery, as well as Chief of the Division of Rheumatology at both HSS and NewYork-Presbyterian/Weill Cornell Medical Center. He is the Franchellie M. Cadwell Professor of Medicine at HSS and the Joseph P. Routh Professor of Rheumatic Diseases in Medicine at Weill Cornell Medicine. 

Dr. Bridges leads 75 full-time physicians, including 38 adult and 5 pediatric rheumatologists. They collectively provide outstanding care to patients across the full spectrum of autoimmune and inflammatory rheumatic diseases and deliver perioperative medical care to patients undergoing surgical procedures at HSS. 

Dr. Bridges鈥 academic and research career has centered on understanding the cellular, molecular, and genetic molecular mechanisms that underlie rheumatoid arthritis, its clinical manifestations, and response to treatment. In particular, he has focused on the role of B lymphocytes and autoantibodies in RA, as well as genetic influences on RA in African Americans. He and his colleagues have defined genetic differences in the MHC and non-MHC genes on susceptibility to RA and on the degree of joint damage between African Americans with RA compared to European and Asian ancestries. More recently, his research program has involved crowdsourcing to facilitate machine learning and big data approaches to answer important clinical questions in RA. 

In addition to his leadership roles at HSS and NYPH/WCMC, Dr. Bridges is President of the Rheumatology Research Foundation and has a concurrent role as a member of the American College of Rheumatology Executive Committee.

Mary Crow, MD

Physician-in-Chief Emerita; Director, Autoimmunity and Inflammation Research Program

Hospital for Special Surgery

Autoimmune Diseases, immune system activation , Lupus, Rheumatoid Arthritis, Rheumatology, Systemic Lupus Erythematosus (SLE)

Dr. Mary Crow, a rheumatologist, is physician-in-chief emerita at Hospital for Special Surgery and a professor of Medicine in the Division of Rheumatology of the Department of Medicine at Weill Cornell Medical College. She is also director of the Autoimmunity and Inflammation Research Program at HSS and co-director of the Mary Kirkland Center for Lupus Research at the HSS Research Institute. Dr. Crow holds the Benjamin M. Rosen Chair in Immunology and Inflammation Research at HSS. She led the HSS Department of Medicine and the Division of Rheumatology in the Department of Medicine at Weill Cornell from 2010 to 2020.

Dr. Crow鈥檚 academic and research career has focused on unraveling the cellular and molecular mechanisms that underlie the systemic autoimmune diseases, with a particular focus on systemic lupus erythematosus and rheumatoid arthritis. She has identified interferon-alpha, an immune system protein typically expressed in the setting of virus infection, as a key pathogenic mediator in lupus. Her laboratory continues to study the triggers of immune system activation in SLE, the molecular pathways associated with the clinical manifestations of lupus, and the mechanisms that result in disease flares. Dr. Crow鈥檚 research has identified therapeutic targets, providing the rationale for the development of novel therapeutic agents for patients with SLE.

In addition to her leadership roles at HSS and WCMC/NYPH, Dr. Crow has served as president of the American College of Rheumatology, as president of the Henry Kunkel Society, and as chair or co-chair of the Scientific Advisory Board of the Alliance for Lupus Research and the Lupus Research Alliance from 2008 to 2019. She has been honored as an 鈥淎rthritis Hero鈥 of the Arthritis Foundation, and in 2010 she received the Margaret D. Smith Lifetime Achievement Award of the Arthritis Foundation, New York Chapter. In 2018 she received the Presidential Gold Medal of the American College of Rheumatology, and in 2019 she was honored as a Notable Woman in Healthcare by Crain鈥檚 New York Business.

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