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Gregory E. Tasian, MD, MSc, MSCE

Gregory E. Tasian, MD, MSc, MSCE

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Children's Hospital of Philadelphia

Attending pediatric urologist in the Division of Urology at Children's Hospital of Philadelphia, Cheers for CHOP Chair in Clinical Epidemiology of Pediatric Urological Disease

Expertise: Chronic Kidney DiseasePediatric Urology

, MD, MSc, MSCE, is an attending pediatric urologist in the Division of Urology at Children's Hospital of Philadelphia. He specializes in the surgical and medical management of children with kidney stones.


As a researcher, Tasian is at the forefront of technological innovation and large-scale data analysis in urology. His lab focuses on identifying the underlying causes of kidney stones and how to develop better strategies for reducing kidney stone recurrence throughout a child’s life. He researches the impact of  on kidney stone disease. His work predicts increased kidney stone cases due to rising temperatures, highlighting the future healthcare burden even with climate change mitigation efforts. Another notable achievement includes the discovery that  increase the risk of kidney stones.

Tasian is also collaborating with colleagues at the University of Pennsylvania’s Perelman School of Medicine to pioneer the use of machine learning to predict pediatric chronic kidney disease progression. His long-term goal is to improve the lives of children with nephrolithiasis and congenital urologic disease, utilizing advanced research methodologies to enhance diagnosis, treatment, and prevention strategies.


 

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Gregory Tasian, an attending pediatric urologist at CHOP, is leading the PUSH study there. He is concerned by the growing number of teens getting kidney stones, both in his practice and nationally. At this point, there aren鈥檛 good population-level numbers for how many adolescents are affected by the condition, but small, regional studies have shown a significant increase over two decades. In particular, Tasian worries about an increasing number of kidney stones in African Americans, among whom the rate is rising at about 5 percent per year. 鈥淲hen you鈥檙e talking about an epidemic, this is something in epidemic proportions,鈥� he said. 鈥淗ow quickly this has changed over such a short period of time is really dramatic.鈥�

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In recent years, hospitals across the country have opened pediatric 鈥渟tone clinics鈥� to keep up with demand, where children can meet with urologists, nephrologists and nutritionists to get the care they need to treat and prevent future kidney stones. Kidney stones in adults are linked to conditions such as metabolic syndrome, obesity, hypertension and diabetes. "In children, we鈥檙e not seeing that," said Dr. Gregory Tasian, a pediatric urologist at Children鈥檚 Hospital of Philadelphia. "They鈥檙e otherwise healthy and simply come in with their first kidney stone for unclear reasons.鈥� Much of the nephrolithiasis research in children in the U.S. has been led by Tasian and his colleagues and is focused on finding the cause. "Clearly something has changed in our environment that is causing this rapid shift,鈥� he said.

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"As the world becomes warmer through climate change, that is expected to increase the number of stones," Dr. Tasian said.

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