麻豆传媒

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Marcel P. Goldschen-Ohm, of the University of Texas at Austin, USA will be honored as the recipient of the Biophysical Journal Paper of the Year-Early Career Investigator Award at the 69th Annual Meeting of the Biophysical Society, held February 15-19 in Los Angeles, California. This award recognizes the work of outstanding early career investigators in biophysics.

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ROCKVILLE, MD - When scientists develop new molecules鈥攚hether for the purposes of agriculture, species control, or life-savings drugs - important to know exactly what its targets are. Thoroughly understanding a molecule's interactions, both intended and unintended, is crucial for ensuring its safety and efficacy.

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Viruses, like those that cause COVID-19 or HIV, are formidable opponents once they invade our bodies. Antiviral treatments strive to block a virus or halt its replication. However, viruses are dynamic - constantly evolving and changing shape, which can make designing antiviral treatments a challenge.

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ROCKVILLE, MD - Tau protein tangles are a hallmark of Alzheimer's, but new research reveals that tau has a critical role in regulating fat metabolism in the brain; when tau become dysfunctional it may promote the buildup of toxic fats, contributing to disrupted fat metabolism and neurodegeneration.鈥淗istorically, neurodegeneration has been studied from the protein side.

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In a surprising discovery, scientists have found that the heart possesses "sweet taste" receptors, similar to those on our tongues, and that stimulating these receptors with sweet substances can modulate the heartbeat. This research opens new avenues for understanding heart function and potentially for developing novel treatments for heart failure.

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ROCKVILLE, MD - Brain inflammation, while a crucial part of the body's immune response, takes on a detrimental role in Alzheimer's disease. Unlike the acute, short-lived inflammation that combats infection, the inflammation associated with Alzheimer's becomes chronic and persistent. Scientists have been trying to understand why this happens.

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ROCKVILLE, MD 鈥� In diseases like Parkinson's and Alzheimer's, specific proteins misfold and clump together, forming toxic aggregates that damage brain cells. The process of proteins spontaneously clumping is called protein aggregation and researchers have developed novel methods to generate aggregate-specific antibodies as specific probes or modulators of the aggregation process.

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Phytoplankton, tiny plant-like organisms in the ocean, are incredibly important for life on Earth. They're a major food source for many sea creatures and produce almost half the oxygen we breathe. They also help control the climate by soaking up a lot of carbon dioxide, a gas that contributes to global warming.

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The Apennine brown bear, also known as the Marsican brown bear (Ursus arctos marsicanus), is a unique and critically endangered subspecies of brown bear found only in the remote and rugged Apennine Mountains of central Italy. A new study by the Italian Endemixit project (endemixit.com) reveals a potentially critical genetic flaw in the endangered Apennine brown bear population of Italy, offering insights that could help boost conservation efforts.

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In a groundbreaking discovery, researchers have identified a novel orphan gene, BOLTING RESISTANCE 2 (BR2), in Chinese cabbage, which plays a pivotal role in delaying bolting by regulating flowering time through the vernalization pathway. This breakthrough is set to transform breeding strategies for one of China鈥檚 most widely cultivated leafy vegetables, addressing a major agricultural challenge that compromises yield and quality in high-latitude and high-altitude regions. By unraveling the genetic mechanisms behind bolting resistance, this study paves the way for the development of more resilient Chinese cabbage varieties, ensuring improved crop performance and food security.