麻豆传媒

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Stopping disruptions in cellular 鈥渢rash removal鈥� brought on by errors in molecular marks on DNA may guard against neurodegenerative diseases like Parkinson鈥檚.

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Two recently discovered compounds have shown promise in preclinical studies for treating Ewing sarcoma, a rare cancer that predominantly affects children and adolescents.

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Clues that point toward new risk mechanisms for developing Parkinson鈥檚 disease are hiding in some unusual spots, according to a study published today in Scientific Reports.

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They鈥檙e two of the biggest mysteries in Parkinson鈥檚 disease research鈥攚here does the disease start? And how can it be stopped early in the process?

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It is known that people who have attempted suicide have ongoing inflammation in their blood and spinal fluid. Now, a collaborative study from research teams in Sweden, the US and Australia published in Translational Psychiatry shows that suicidal patients have a reduced activity of an enzyme that regulates inflammation and its byproducts.

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A simple adjustment to patients鈥� therapeutic regimen may improve the effectiveness of the standard epigenetic treatment for myeloid dysplastic syndrome (MDS) and acute myeloid leukemia (AML).

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Type II diabetes and Parkinson鈥檚 disease may not appear to have much in common but a look below the surface reveals important molecular similarities that provide a potential target for fighting Parkinson鈥檚.

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A new computational tool called fABMACS is helping scientists see beyond static images of proteins to more efficiently understand how these molecules function, which could ultimately speed up the drug discovery process.

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A new investigational drug originally developed for type 2 diabetes is being readied for human clinical trials in search of the world鈥檚 first treatment to impede the progression of Parkinson鈥檚 disease following publication of research findings today in the journal Science Translational Medicine.

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A comprehensive analysis of 559 esophageal and gastric cancer samples, collected from patients around the world, suggests the two main types of esophageal cancer differ markedly in their molecular characteristics and should be considered separate diseases.