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Alzheimer-like changes 鈥� marked by the build-up of harmful amyloid and tau proteins 鈥� occur in the brain in Down syndrome has been unclear. But now, in new research, scientists at the Lewis Katz School of Medicine at Temple University show that reduced efficiency of a key protein transport system is partly to blame.
A new approach could enhance memory and learning in individuals with Down syndrome by stabilizing a key component in the body's protein sorting system called the retromer complex.
A recent study has used Artificial Intelligence (AI) to reveal the remarkable potential of extra virgin olive oil (EVOO) in the fight against Alzheimer's disease (AD). Researchers combined AI technology, chemistry, and omics research to identify specific bioactive compounds in EVOO that show promising effects in treating and preventing AD.
A recent study shows that a protein called ABCA7 plays a functional role as a potential biological link between cholesterol and inflammation in Alzheimer鈥檚 disease. The new work was published online August 25 in the journal Cells.
鈥淭here is abundant evidence of a link between contact sports, such as football, and dementia later in life,鈥� comments Domenico Pratico, M.D., Director of the Alzheimer鈥檚 Center at Temple University (ACT).
鈥淎re the risk factors for early onset Alzheimer鈥檚 the same as late onset?鈥� asks Domenico Pratic貌, MD, the Scott Richards North Star Foundation Chair for Alzheimer鈥檚 Research, Professor in the Departments of Pharmacology and Microbiology, and Director of the Alzheimer鈥檚 Center at Temple (ACT), at the Lewis Katz School of Medicine at Temple University (LKSOM)
鈥淎I-driven neuroimaging techniques have the potential to improve prediction models for Alzheimer鈥檚 progression and facilitate personalized treatment strategies,鈥� says Domenico Pratic貌, MD, the Scott Richards North Star Foundation Chair for Alzheimer鈥檚 Research, Professor in the Departments of Pharmacology and Microbiology, and Director of the Alzheimer鈥檚 Center at Temple (ACT), at the Lewis Katz School of Medicine at Temple University (LKSOM).
People aged 60-80 with low levels of the protein ABCA7 in the brain appear more likely to develop Alzheimer鈥檚 disease, according to a new study published in the Journal of Neuropathology & Experimental Neurology.
Researchers working with the Alzheimer鈥檚 Center at Temple (ACT) recently investigated the effect of extra virgin olive oil (EVOO) on brain health and memory to determine if consumption of extra virgin olive oil, the main component of the Mediterranean diet, can delay cognitive decline in people with Down Syndrome (DS).
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