麻豆传媒

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Memorial Sloan-Kettering Cancer Center scientists have achieved a major milestone: the first-ever molecular "snapshot" of a new drug interacting with its cellular target.

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Researchers at Memorial Sloan-Kettering Cancer Center have found that cancer tumors consume large amounts of vitamin C, they reported in the September 15 issue of Cancer Research.

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Although it has been known that a mutation in both copies of the PTEN tumor suppressor gene impairs a cell's ability to program its death, researchers have found that losing function of only one of the pair is enough to disrupt this vital signaling mechanism.

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Research conducted by Memorial Sloan-Kettering Cancer Center investigators sheds new light on why existing therapies don't stop the prostate cancer from returning and was published in the November 3rd issue of the Journal of the National Cancer Institute.

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Memorial Sloan-Kettering Cancer Center researchers have shown that a new combination treatment increases the number of patients with non-Hodgkin's lymphoma (NHL) who can receive potentially curative bone marrow transplantation.

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A genetic mutation may account for up to nine percent of the colon cancer cases diagnosed in the United States, report scientists at Memorial Sloan-Kettering Cancer Center and other research centers in the November 15 issue of Cancer Research.

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A treatment combining traditional chemotherapy with medication delivered through a surgically implanted pump has been found to increase life expectancy in patients with advanced colorectal cancer that has spread to the liver, reports an oncologist at Memorial Sloan-Kettering Cancer Center.

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Researchers at Memorial Sloan-Kettering Cancer Center report the development of a new chemotherapy regimen for first line treatment for patients with metastatic colorectal cancer. (New England Journal of Medicine, 9-28-00)

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"Knocking out" a particular gene protects the ovaries of mice from damage, researchers at Memorial Sloan-Kettering Cancer Center, along with colleagues from Massachusetts General Hospital and other institutions, have discovered. (Nature Medicine, 10-00)

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A new prognostic tool, developed at Memorial Sloan-Kettering Cancer Center, could aid physicians and patients in decision making regarding treatment options for early stage prostate cancer and in identifying those patients who are at high risk of recurrence following radiation therapy. (Journal of Clinical Oncology, 9-28-00)