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"It's not everyday that one newly discovers parts of the human body," says Roy S. Chuck, MD, PhD, Chairman Department of Ophthalmology and Visual Sciences, Albert Einstein College of Medicine.
RPB-supported researchers have made a significant discovery that might lead to the delay or prevention of the most common cause of blindness in the elderly: age-related macular degeneration (AMD). Patients who take the drug L-DOPA (for Parkinson Disease, Restless Legs or other movement disorders) are significantly less likely to develop AMD and, if they do, it is at a significantly later age.
Researchers believe that adults whose eyes are slow to adjust to the dark have a greater risk of developing age-related macular degeneration.
As medical professionals search for new ways to personalize diagnosis and treatment of disease, RPB-supported researchers at the University of Iowa have already put into practice what may be the next big step in precision medicine: personalized proteomics.
Researchers at Washington University School of Medicine in St. Louis published a study that shows that genetic material from the Zika virus has been found in tears. The study, fast-tracked for publication in Cell Reports, was conducted in mice, thereby creating an animal model for studying transmission and treatment of this alarming virus. The study, published September 6, 2016, also confirms that the Zika virus can lead to cell death in the eyes. Research to Prevent Blindness, located in New York, provided funding for this study.
A common pathway involved in photoreceptor death has been identified in retinitis pigmentosa, advanced dry age-related macular degeneration and other retinal diseases, with early evidence of a possible halt to vision loss related to treatment of the pathway.
RPB-supported vision researchers at Washington University School of Medicine in St. Louis have contributed key data to a new study that identifies a natural compound that slows typical signs of aging in mice. The study, published today in Cell Metabolism, shows that older mice drinking water supplemented with NMN (nicotinamide mononucleotide) resembled younger mice in measures of metabolism and energy production.
Scientists at the Wayne State University School of Medicine Department of Ophthalmology at the Kresge Eye Institute have shown that the Zika virus can replicate in the eye鈥檚 retinal cells, causing severe tissue damage and even blindness. The research is supported in part by Research to Prevent Blindness.
On May 4th, RPB-supported researchers at Washington University School of Medicine in St. Louis published a study identifying a biomarker that could help to predict glaucoma damage before vision loss.
RPB-supported researchers at the University of Illinois at Chicago have identified an enzyme present in the cornea that triggers inflammation during and even after a herpes virus infection has cleared. Their results are published in the journal Cell Reports.
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