麻豆传媒

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A team of Harvard Medical School and Howard Hughes ivestigators has gotten to the heart of the problem of how an organ develops and acquires its characteristic shape. They have identified a gene called Irx-4 that opens doors to understanding how the heart chambers form. The findings appear in the February 19 Science.

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Mice lacking a gene for making telomeres -- chromosomal elements with a conjectured but controversial role in aging and cancer -- were found to go gray, lose hair faster, and recover less easily from the stress of surgery and chemotherapy than normal animals, reports a team of Dana-Farber Cancer Institute and Harvard Medical School researchers.

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Harvard Medical School/Howard Hughes Medical Institute researchers have found that the transferrin cycle has a more limited role in iron transport than previously believed. The findings may lead to improved diagnosis and treatment of iron metabolism disorders.

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A mechanism the immune system uses to detect and eliminate dysfunctional T cells has been identified by Dana-Farber Cancer Institute and Harvard Medical School researcher reported in the May 14 Science. The study clarifies a long-standing puzzle about the development of systemic autoimmune diseases.

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1. Project Success: Hands-on Science For High School and College Students 2. History of Medicine Exhibit: Magical Stones and Imperial Bones 3. Center for Conservation Medicine Studies Ecosystem-Human Health 4. Addressing the Mental Health Needs of Indigenous People.

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Teaming tumor-attacking viruses with an approved chemotherapeutic drug may be more effective than either agent alone for treating multi-site brain cancers, reports a team of Massachusetts General Hospital and Harvard Medical School researchers.

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One in four Bosnian adults who fled the Bosnia-Herzegovina war may be functionally disabled due to psychiatric disorders, according to a study from Harvard Medical School and the Harvard Program in Refugee Trauma. The findings underline the need to address mental health issues when creating redevelopment programs in war-torn countries.

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According to a study in the August 17 Annals of Internal Medicine, physician guidelines are inadequate in helping physicians counsel women about whether to take postmenopausal estrogen replacement therapy. The study's authors say that future guidelines should instruct physicians to incorporate patients' perspectives into the counseling process.

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From the belly to the brain, a new study by Boston researchers shows how the fat hormone leptin works in the brain to trigger the nerve cells that control eating. The study adds important details about how leptin, which is released into the blood stream from fat, may control the cognitive aspects of feeding behavior.

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The timeliness and quality of care for elderly patients with acute myocardial infarction who are covered by non-profit health maintenance organizations is equal to, or better than, the care provided under fee-for-service insurance, according to Harvard researchers.