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17-Feb-1999 12:00 AM EST
Researchers Report Emergence of Antibiotic Resistance during Vancomycin Therapy
Rockefeller University

A team of researchers led by The Rockefeller University's Alexander Tomasz, Ph.D., have described the case of a 79-year-old patient whose death in a New York metropolitan area hospital last March was associated with a bloodstream infection caused by a multidrug-resistant strain of Staphylococcus aureus.

15-Jul-1999 12:00 AM EDT
Injected Cells Boost Immune System in Humans
Rockefeller University

A single injection of specialized immune system cells can trigger a potent immune response in humans that lasts for months, Rockefeller University researchers report.

Released: 21-Apr-2000 12:00 AM EDT
Penicillin-Resistance Gene in Pneumonia Bacteria
Rockefeller University

Antibiotic resistance in pneumococcus can be stopped by inactivating a pair of genes responsible for producing molecules called branched muropeptides, say Rockefeller researchers (Proceedings of the National Academy of Sciences, 4-25-00).

Released: 16-Sep-2000 12:00 AM EDT
Why Experimental Leukemia Drug, STI-571, Is Effective
Rockefeller University

Research from the Howard Hughes Medical Institute at The Rockefeller University, the Memorial Sloan-Kettering Cancer Center and the State University of New York at Stony Brook shows how the experimental drug STI-571 selectively blocks a mutant enzyme that causes a rare form of leukemia without harming its molecular cousins

Released: 9-Aug-2001 12:00 AM EDT
Widespread Superbug is Expert at Acquiring Drug-Resistance
Rockefeller University

One of the most widely disseminated strains of an antibiotic-resistant bacterium responsible for hundreds of infections in European hospitals can be traced back to the 1950s, according to researchers at The Rockefeller University.

Released: 22-Aug-2001 12:00 AM EDT
New Model of Staph Drug Resistance Points to Unlikely Protein
Rockefeller University

Researchers at The Rockefeller University have established a new model to explain how the infectious "staph" bacterium evades several widely used antibiotics. They show that a protein previously thought to play no role in drug resistance in Staphylococcus aureus is, in fact, essential.

9-Oct-2001 12:00 AM EDT
Trigger Found for Killer T Cells to Attack
Rockefeller University

How do "killer T cells" know when to attack virus-infected and cancerous cells, and when to retreat? The answer possibly has been provided by Rockefeller University research.

Released: 3-Nov-2001 12:00 AM EST
Atomic-size Sorter That Performs Vital Cellular Function
Rockefeller University

Scientists are now able to "see" a structure that acts as an atomic-size sorter for cells. Without it, many important life functions--nerve signal firing, heartbeat, hormone secretion--could not occur.

16-Nov-2001 12:00 AM EST
Molecular Basis of Mental Retardation Uncovered
Rockefeller University

Scientists at last may have determined how mental retardation develops in people with fragile X syndrome, a condition caused by the inherited loss of an essential protein, termed the fragile X mental retardation protein (FMRP).

7-Dec-2001 12:00 AM EST
Bacteria's Natural Foe Fights Drug-Resistant Infections
Rockefeller University

Scientists have turned to nature once again for help in fighting deadly infections. Rockefeller University researchers show that a natural enzyme derived from tiny viruses that live inside bacteria can successfully target and kill disease bacteria, including those that are resistant to drugs.


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