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Released: 26-Feb-2025 4:00 PM EST
Drug May Prevent Some Migraine Attacks in Children and Teens
American Academy of Neurology (AAN)

For children and teens living with migraine, there may be a new preventive treatment, according to a preliminary study released today, February 26, 2025, that will be presented at the American Academy of Neurology’s 77th Annual Meeting taking place April 5–9, 2025, in San Diego and online. Researchers found the drug zonisamide, which has been used to treat seizures, may reduce migraine days in this age group. This study does not prove that zonisamide reduces migraine days; it only shows an association.

Released: 26-Feb-2025 4:00 PM EST
Blood Test Could Lead to Better Diagnosis and Management of ALS
American Academy of Neurology (AAN)

ALS, or amyotrophic lateral sclerosis, can sometimes be difficult to diagnose or to predict how quickly the disease is likely to progress. A new study helps determine which blood tests are best at identifying and monitoring ALS. The study is published in the February 26, 2025, online issue of Neurology®, the medical journal of the American Academy of Neurology.

鶹ý: Problem-Based Learning Helps Students Stay in School
Released: 26-Feb-2025 3:30 PM EST
Problem-Based Learning Helps Students Stay in School
University of South Australia

Education experts at the University of South Australia are encouraging schools to consider problem-based learning (PBL) in a move to improve engagement and creativity among high school students. The call follows new Productivity Commission data that shows national school attendance rates over the past year have decreased from 88.8% in Year 7 to 84% in Year 10. Government schools are worst hit, with only 73% of public-school students completing year 12, as compared with nearly 80% in 2017.

Released: 26-Feb-2025 12:00 PM EST
Asthma and Stem Cell Therapy
World Journal of Stem Cells

The global incidence of asthma, a leading respiratory disorder affecting more than 235 million people, has dramatically increased in recent years. Characterized by chronic airway inflammation and an imbalanced response to airborne irritants

Released: 26-Feb-2025 12:00 PM EST
Fetal Mice Dermal Mesenchymal Stem Cells Promote Wound Healing by Inducing M2 Type Macrophage Polarization
World Journal of Stem Cells

BACKGROUNDMesenchymal stem cells, found in various tissues, possess significant healing and immunomodulatory properties, influencing macrophage polarization, which is essential for wound repair. However, chronic wounds present significant t

Released: 26-Feb-2025 12:00 PM EST
WDR36 Inhibits the Osteogenic Differentiation and Migration of Periodontal Ligament Stem Cells
World Journal of Stem Cells

BACKGROUNDPeriodontitis is an inflammatory disease caused by the host’s immune response and various interactions between pathogens, which lead to the loss of connective tissue and bone. In recent years, mesenchymal stem cell (SC) transpla

Released: 26-Feb-2025 12:00 PM EST
Effects of Macrophages on the Osteogenic Differentiation of Adipose Tissue-Derived Stem Cells in Two-Dimensional and Three-Dimensional Cocultures
World Journal of Stem Cells

BACKGROUNDFracture is one of the most pervasive injuries in the musculoskeletal system, and there is a complex interaction between macrophages and adipose tissue-derived stem cells (ADSCs) in fracture healing. However, two-dimensional (2D)

Released: 26-Feb-2025 12:00 PM EST
Impact of miR-214-5p and miR-21-5p From Hypoxic Endometrial Exosomes on Human Umbilical Cord Mesenchymal Stem Cell Function
World Journal of Stem Cells

Exosomes derived from hypoxic endometrial epithelial cells are pivotal in cellular communication and tissue repair, offering new perspectives on reproductive health. This manuscript highlights the study by Zhang et al, which investigates th

Released: 26-Feb-2025 12:00 PM EST
Induced pluripotent stem cell-derived mesenchymal stem cells for modeling and treating metabolic associated fatty liver disease and metabolic associated steatohepatitis: Challenges and opportunities
World Journal of Stem Cells

The potential of induced pluripotent stem cells (iPSCs) for modeling and treating metabolic associated fatty liver disease (MAFLD) and metabolic associated steatohepatitis (MASH) is emerging. MAFLD is a growing global health concern, curren

Released: 26-Feb-2025 12:00 PM EST
Perspectives on Schwann-Like Cells Derived From Bone Marrow-Mesenchymal Stem Cells: Advancing Peripheral Nerve Injury Therapies
World Journal of Stem Cells

Peripheral nerve injuries are clinical conditions that often result in functional deficits, compromising patient quality of life. Given the relevance of these injuries, new treatment strategies are constantly being investigated. Although me

Released: 26-Feb-2025 12:00 PM EST
Stem Cell Therapy: A Promising Therapeutic Approach for Skeletal Muscle Atrophy
World Journal of Stem Cells

Skeletal muscle atrophy results from disruptions in the growth and metabolism of striated muscle, leading to a reduction or loss of muscle fibers. This condition not only significantly impacts patients’ quality of life but also imposes su

Released: 26-Feb-2025 12:00 PM EST
Effect of adipose-derived stem cells exosomes cross-linked chitosan-αβ-glycerophosphate thermosensitive hydrogel on deep burn wounds
World Journal of Stem Cells

BACKGROUNDBurn wound management is challenging, and while mesenchymal stem cell-derived exosomes show therapeutic potential, optimal delivery methods are unclear. AIMTo study chitosan (CS)-αβ-glycerophosphate (CS-αβ-GP) hydrogel crossl

Released: 26-Feb-2025 12:00 PM EST
Effect of Tandem Autologous Stem Cell Transplantation on Survival in Pediatric Patients with High-Risk Solid Tumors in South China
World Journal of Stem Cells

BACKGROUNDDespite advances in treatment, the prognosis for patients with high-risk pediatric solid tumors remains dismal. Tandem autologous stem cell transplantation (ASCT) offers promise for improving outcomes in these patients. This study

Released: 26-Feb-2025 12:00 PM EST
Exosomal miR-203 Bone Marrow Stem Cells Targets the SOCS3/NF-κB Pathway to Regulate Neuroinflammation in Temporal Lobe Epilepsy
World Journal of Stem Cells

BACKGROUNDEpilepsy is a prevalent chronic neurological disorder affecting 50 million individuals globally, with temporal lobe epilepsy (TLE) being the most common form. Despite advances in antiepileptic drug development, over 30% of patient

Released: 26-Feb-2025 12:00 PM EST
Nicotinamide Adenine Dinucleotide Rejuvenates Septic Bone Marrow Mesenchymal Stem Cells
World Journal of Stem Cells

BACKGROUNDSepsis is a severe illness characterized by systemic and multiorgan reactive responses and damage. However, the impact of sepsis on the bone marrow, particularly on bone marrow mesenchymal stem cells (BMSCs), is less reported. BMS

鶹ý: Female Physicians at Elevated Risk for Suicide
Released: 26-Feb-2025 11:30 AM EST
Female Physicians at Elevated Risk for Suicide
University of California San Diego

Many physicians struggle with depression and burnout, and now researchers at University of California San Diego School of Medicine have found that female physicians in the U.S. had a 53% higher suicide risk compared to females in the general population.

鶹ý: Cycle for Survival Surpasses $400 Million Raised for Rare Cancer Research
Released: 26-Feb-2025 11:00 AM EST
Cycle for Survival Surpasses $400 Million Raised for Rare Cancer Research
Cycle for Survival

Cycle for Survival Surpasses $400 Million Raised for Rare Cancer Research

Released: 26-Feb-2025 11:00 AM EST
ADLM Urges Congress to Improve Children’s Access to High Quality Clinical Laboratory Testing
Association for Diagnostic and Laboratory Medicine (ADLM (formerly AACC))

The Association for Diagnostics & Laboratory Medicine (ADLM, formerly AACC) released a position statement today emphasizing that limited access to quality clinical laboratory services is impeding children’s health, and that action must be taken to address this significant problem.

鶹ý: New Photon-Avalanching Nanoparticles Could Enable Next-Generation Optical Computers
Released: 26-Feb-2025 11:00 AM EST
New Photon-Avalanching Nanoparticles Could Enable Next-Generation Optical Computers
Lawrence Berkeley National Laboratory

Researchers have developed a new optical computing material from photon-avalanching nanoparticles. The breakthrough offers a path toward realizing smaller, faster components for next-generation computers.



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