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A powerful new software platform called the Playbook Workflow Builder is set to transform biomedical research by allowing scientists to conduct complex and customized data analyses without advanced programming skills. An article that describes the new platform was published in the April 3 online issue of the journal PLOS Computational Biology. Developed by a multi-institutional team that was led by Icahn School of Medicine at Mount Sinai investigators as part of the National Institutes of Health Common Fund Data Ecosystem (CFDE) program, researchers from across the United States developed the web-based platform that enables scientists to analyze and visualize their own data independently through an intuitive, interactive interface.

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"I, Ovosan" offers inspiring cancer survivor stories interwoven with cutting-edge research, detailing the development and therapeutic potential of Ovosan's bioactive phospholipids, now available in the US as CellBB.

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Nobel Laureate James Rothman, PhD; Holly A. Ingraham, PhD, FASEB鈥檚 2024 Lifetime Achievement awardee; and George A. Brooks, PhD, FAPS, the American Physiological Society鈥檚 (APS) 2025 Walter Cannon Award recipient, are among the highlighted speakers who will attend the American Physiology Summit. The Summit, APS鈥� flagship annual meeting, will be held April 24鈥�27 in Baltimore.

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Together, the two organizations have created a unique alliance that blends the academic prowess of LJI with the drug development and commercialization expertise of Kyowa Kirin.

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The Icahn School of Medicine at Mount Sinai has launched the AI Small Molecule Drug Discovery Center, a bold endeavor that harnesses artificial intelligence (AI) to revolutionize drug development. The new Center will integrate AI with traditional drug discovery methods to identify and design new small-molecule therapeutics with unprecedented speed and precision. Unlike conventional drug discovery, which can take years and cost billions, AI-driven approaches enable researchers to rapidly navigate a vast chemical landscape, including natural products, to pinpoint promising drug candidates. By leveraging Mount Sinai鈥檚 world-leading expertise in machine learning, chemical biology, and biomedical data science, the Center aims to bring innovative treatments to patients faster鈥攑articularly for diseases with urgent unmet needs, including cancer, metabolic disorders, and neurodegenerative diseases.

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Exposure to antibiotics during infancy can stunt the growth of insulin-producing cells in the pancreas and may boost risk of diabetes later in life. The findings shine a light on the importance of the infant microbiome and could lead to new approaches for addressing metabolic diseases.

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Recognizing their outstanding contribution to Canada or on the international stage, the medal commemorates the crowning of the former Prince of Wales in 2022.

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Joseph A. Barone, dean of Rutgers Ernest Mario School of Pharmacy, was presented with the Bowl of Hygeia Award from the American Pharmacists Association and the New Jersey Pharmacists Association

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Moores Cancer Center at the University of California San Diego has received a $1 million donation from pharmaceutical company Pfizer to support an innovative new program designed to bolster early cancer detection and prevention efforts. The donation will help build a bridge bringing research discoveries to community health centers and improving access to early detection tests for colorectal, breast, cervical and prostate cancer.

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Engenheiros de manufatura est茫o na vanguarda de trazer novos medicamentos derivados de fontes humanas, como c茅lulas, sangue e genes, para os pacientes. Eles produzem o que muitas vezes s茫o bioterapias pioneiras do seu tipo para doen莽as que anteriormente tinham poucas ou nenhuma op莽茫o de tratamento.

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Manufacturing engineers are at the forefront of bringing new medicines derived from human sources such as cells, blood and genes to patients. They produce what are often first-of-their kind biotherapies for diseases that previously had few or no treatment options.

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JACKSONVILLE, Florida 鈥� Ingenieros de manufactura est谩n a la vanguardia de llevar nuevos medicamentos derivados de fuentes humanas, como c茅lulas, sangre y genes, a los pacientes. Ellos producen lo que a menudo son bioterapias pioneras de su tipo para enfermedades que anteriormente ten铆an pocas o ninguna opci贸n de tratamiento.

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Risk management expert Clifford Rossi warns that pharma tariffs could disrupt supply chains, raise costs, and pressure manufacturers, especially generics. Adopting continuous manufacturing offers efficiency gains, balancing risk mitigation with strategic investment.

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A McMaster University team led by renowned researcher Gerry Wright has identified a strong candidate to challenge even some of the most drug-resistant bacteria on the planet: a new molecule called lariocidin.

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This comprehensive review analyzes cutting-edge tools and technologies in modern pharmaceutical research, focusing on artificial intelligence, multi-omics technologies, and experimental methods. The study highlights how computational methods enhance drug discovery efficiency, while omics technologies provide systematic frameworks for investigating drug mechanisms. The integration of these advanced approaches has enabled more diverse and personalized treatment strategies, though challenges remain in drug development complexity, cost-effectiveness, and operational feasibility.

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Las bases de maquillaje m谩s oscuras suelen fallar de plano, ya que dan un aspecto gris谩ceo al aplicarlas sobre la piel. Pero ahora, los investigadores informan de un aditivo de color azul para cosm茅ticos que proporciona a las bases m谩s oscuras la calidez e intensidad de las que carecen las f贸rmulas actuales. Presentar谩n sus resultados en el encuentro de primavera de 2025 de la ACS.

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Darker makeup foundations often fall flat, appearing gray-like once applied on the skin. But now, researchers report a blue cosmetic color additive that gives darker foundations the warmth and depth that current formulations lack. They will present their results at ACS Spring 2025.

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Phenomenex Introduces Biozen鈩� Native RP-1 and RP-5: A Novel Way to Characterize ADCs with Unmatched Throughput and High-Quality Data