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Researchers have introduced improved cognitive tests to assess dementia in older Africans, part of the HAALSI-HCAP study in rural South Africa. These tools, tailored for local contexts, enhance global ageing research and could inform a national survey. With dementia rates rising, findings will aid prevention and policy.
賷賵丕噩賴 兀睾賱亘 賲乇囟賶 丿丕亍 丕賱夭賴丕賷賲乇 賵丕賱禺賻乇賻賮 丕賱賲乇鬲亘胤 亘丿丕亍 丕賱夭賴丕賷賲乇 丕賱馗賴賵乇 賵丕賱鬲賯丿賲 丕賱鬲丿乇賷噩賷賳 賱賱兀毓乇丕囟 丕賱廿丿乇丕賰賷丞貙 賲賲丕 賷爻亘亘 丕賱鬲丿賴賵乇 毓賱賶 賲丿賶 爻賳賵丕鬲 兀賵 毓賯賵丿. 廿賱丕 兀賳賴 賮賷 賲噩賲賵毓丞 賮乇毓賷丞 氐睾賷乇丞 賲賳 丕賱賲乇囟賶 鬲亘丿兀 丕賱兀毓乇丕囟 爻乇賷毓賸丕貙 賲丐丿賷丞賸 廿賱賶 丕賱廿氐丕亘丞 亘丕賱禺賻乇賻賮 賮賷 睾囟賵賳 爻賳丞 賵丕丨丿丞 賵丕賱毓噩夭 丕賱賰丕賲賱 禺賱丕賱 爻賳鬲賷賳 賲賳 亘丿丕賷丞 馗賴賵乇 丕賱兀毓乇丕囟. 賵鬲胤賲丨 丿乇丕爻丞 噩丿賷丿丞 鬲購噩乇賶 賮賷 賲丕賷賵 賰賱賷賳賰 廿賱賶 鬲丨丿賷丿 爻亘亘 廿氐丕亘丞 賲乇囟賶 丿丕亍 丕賱夭賴丕賷賲乇 賵丕賱禺賻乇賻賮 丕賱賲乇鬲亘胤 亘丿丕亍 丕賱夭賴丕賷賲乇 亘賴匕丕 丕賱禺賻乇賻賮 爻乇賷毓 丕賱鬲賯丿賲.
A maioria dos pacientes com doen莽a de Alzheimer (DA) e dem锚ncias relacionadas 脿 doen莽a de Alzheimer (DRDA) experimenta o in铆cio gradual e a progress茫o dos sintomas cognitivos, levando-os ao decl铆nio ao longo dos anos ou das d茅cadas. No entanto, em um pequeno subconjunto de pacientes, os sintomas come莽am rapidamente, levando 脿 dem锚ncia dentro de um ano e 脿 incapacidade total dentro de dois anos ap贸s o in铆cio dos sintomas. Um novo estudo na Mayo Clinic tem como objetivo determinar por que pacientes com a doen莽a de Alzheimer e DRDA desenvolvem essa dem锚ncia rapidamente progressiva (DRP).
La mayor铆a de los pacientes con enfermedad de Alzheimer (EA) y enfermedad de alzheimer y las demencias relacionadas (DRDA, por sus siglas en ingl茅s) experimenta el inicio gradual y la progresi贸n de los s铆ntomas cognitivos, lo que los lleva al deterioro a lo largo de los a帽os o d茅cadas. Sin embargo, en un peque帽o subconjunto de pacientes, los s铆ntomas comienzan r谩pidamente, lo que lleva a la demencia dentro de un a帽o y a la discapacidad total dentro de los dos a帽os posteriores al inicio de los s铆ntomas. Un nuevo estudio en Mayo Clinic tiene como objetivo determinar por qu茅 los pacientes con la enfermedad de Alzheimer y DRDA desarrollan esta demencia r谩pidamente progresiva (DRP).
Most patients with Alzheimer's disease and Alzheimer's Disease Related Dementias (ADRD) experience the gradual onset and progression of cognitive symptoms, leading to decline over years or decades. However, in a small subset of patients, symptoms begin rapidly, leading to dementia within one year and complete incapacitation within two years of symptom onset.
A newly developed blood test for Alzheimer鈥檚 disease not only aids in the diagnosis of the neurodegenerative condition but also indicates how far it has progressed, according to a study by researchers at Washington University School of Medicine in St. Louis and Lund University in Sweden.
Type 2 diabetes may rewire the brain in ways that mimic early Alzheimer鈥檚 disease 鈥� and UNLV researchers say the 鈥渨hy鈥� may lie in a previously unexplored connection between high blood sugar levels and a key part of the brain called the anterior cingulate cortex (ACC).
MINNEAPOLIS 鈥� People who have early signs of heart problems may also have changes in brain health that can be early signs of dementia, such as loss of brain volume, according to a meta-analysis published on March 26, 2025, online in Neurology庐, the medical journal of the American Academy of Neurology. The meta-analysis does not prove that early heart problems cause loss of brain cells; it only shows an association.
People living in more disadvantaged neighborhoods may be more likely to develop dementia than people living in neighborhoods with fewer disadvantages, according to a study published on March 26, 2025, online in Neurology庐, the medical journal of the American Academy of Neurology.
Stroke survivors who have attended some level of higher education may face even steeper mental declines, according to a study led by Michigan Medicine. The findings suggest that attending higher education may enable people to retain greater cognitive ability until a critical threshold of brain injury is reached after a stroke.
Researchers have introduced specialised dementia tests tailored for older African adults, improving on standard cognitive assessments. These tools, part of HAALSI-HCAP, aim to address data gaps in Africa's ageing studies. The initiative aligns with global efforts and may inform national dementia surveys in South Africa.
To determine the underlying causes of neuronal vulnerability at the earliest stages of Alzheimer's disease (AD), a research team from the UC San Francisco鈥檚 Memory & Aging Center made use of brain tissue samples from two brain regions with differing susceptibility to AD.
West Virginia University neuroscientists have discovered a way to control how much zinc is released to specific locations in the brain. The essential mineral plays a major role in the organ鈥檚 function, including improving memory and lessening symptoms of some neurological disorders, but getting the right amount to the right place is key.
An experimental drug appears to reduce the risk of Alzheimer鈥檚-related dementia in people destined to develop the disease in their 30s, 40s or 50s, according to the results of a study led by the Knight Family Dominantly Inherited Alzheimer Network-Trials Unit (DIAN-TU), which is based at WashU Medicine.
For women in their 80s, experiencing increasing sleepiness during the day over a five-year period is associated with double the risk of developing dementia during that time, according to a study published on March 19, 2025, online in Neurology庐, the medical journal of the American Academy of Neurology. The study does not prove that daytime sleepiness causes dementia; it only shows an association.
A stem cell therapy trial aimed at reducing neuroinflammation in patients with presymptomatic Alzheimer鈥檚 disease is underway at UTHealth Houston.
A study by a team of University of West Florida researchers, conducted with Council on Aging of West Florida鈥檚 adult day care, The Retreat, uncovered insights into the positive impact of dance on individuals living with Alzheimer鈥檚 and related dementias.
Spatial transcriptomics is a cutting-edge technique that characterizes gene expression within sections of tissue, such as heart, skin or liver tissue. Scientists at St. Jude and the University of Wisconsin-Madison today share a generative algorithm for achieving both high genome and image resolution.
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Case Western Reserve University researchers are testing an AI-powered robot named Ruyi to support seniors with early-stage Alzheimer鈥檚.
Long-term and precise intracellular signal detection is critical for advancing our understanding of brain diseases and developing effective diagnostic tools. A breakthrough method has been introduced to enhance the stability and fidelity of recording signals at the single-cell level using ultrafine electrodes (UME). By controlling the tip exposure of UMEs, researchers have demonstrated a significant improvement in their ability to resist environmental interference, thus improving signal-to-noise ratio and sensitivity, and the collection area has been precisely controlled. This method promises to enhance the performance of implantable neural interfaces for real-time monitoring of intracellular signals.
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