Rapidly Assessing Data-Poor Chemicals
Society of Toxicology
The awardees have made significant contributions to advancing the science of toxicology, earning recognition for their groundbreaking achievements.
The July 2024 issue of Toxicological Sciences includes a Contemporary Review on AHR-signaling, an In-Depth Review on allergic reactions, and Tox Spotlight articles on physiologically based kinetic models and neonatal exposure to a flame retardant.
Among the accomplishments of this year鈥檚 awardees are discoveries related to the role of altered pharmacokinetics in non-alcoholic fatty liver disease, the mechanisms of Parkinson鈥檚 disease neurodegeneration, the risk of COVID-19 to smokers and vapers, and the role of the microbiome in pregnancy and early developmental programming.
The December 2023 issue of ToxSci features a Contemporary Review exploring lipid mediator鈥揹riven inflammation following air pollution exposure, an In-Depth Review on the state of in vitro skin models, and ToxSpotlights on the effects of inhalation exposure to TCE and the dose-response assessment of non-mutagenic liver carcinogens.
The November 2023 issue of Toxicological Sciences includes ToxSpotlight articles that examine the renal proximal tubule microphysiological system as an in vitro model for drug transport and toxicity studies and an integrated approach for early in vitro seizure prediction utilizing hiPSC neurons and human ion channel assays.
The latest issue of Toxicological Sciences includes papers on phthalate and lead exposures, machine learning, the long-lasting effects of prenatal exposure to diethylstilbestrol on fertility and reproduction, and more.
New issue of Toxicological Sciences features a Systematic Review on PFAS exposure during breastfeeding, an In-Depth Review on PFAS toxicokinetics and modes of action, and spotlight articles on an in vitro rat airway epithelial model and on risk estimates for lead based on drinking water, genetics, and diet.
The May 2023 issue of Toxicological Sciences includes articles on profiling mechanisms that drive acute oral toxicity in mammals and its prediction via machine learning and how vinyl chloride enhances high-fat diet-induced proteome alterations in the mouse pancreas related to metabolic dysfunction.
Papers on the use of AI in physiologically based pharmacokinetic modeling, how mild allergic airway responses may increase cardiovascular risk, and how single-cell transcriptomes can show dose-dependent disruption of hepatic zonation by TCDD are featured in lastest issue of Toxicological Sciences.
Over the last 50+ years, the SOT Awards have honored visionary toxicologists, exemplary early career scientists, and outstanding postdocs and students. That tradition continues this year as SOT recognizes individuals who have and are advancing the field of toxicology in extraordinary ways.
The December 2022 issue features 10 articles on the latest research in toxicology.
A ToxSpotlight article in the November 2022 issue of ToxSci assesses the mechanism for cellular accumulation of diglycolic acid while another explores the effect of long-term St. John鈥檚 wort administration on acetaminophen-induced acute hepatotoxicity and the involved mechanisms.
Other featured research in October 2022 issue involves an exploration of a pharmacokinetic model for quantifying the mother-to-child transfer of environmental chemicals and how febuxostat may increase the risk for cardiovascular events by dysregulating calcium dynamics.
Cannabinoid vaping products, genomic biomarkers to determine tumorigenic potential, and analyses of various testing assays are just a few of the article topics in the July 2022 issue of Toxicological Sciences.
The June 2022 issue of Toxicological Sciences contains cutting-edge toxicology research in topics such as biomarkers; DART; and emerging technologies, methods, and models.